Browsing by Subject "Phage display"

Now showing items 1-10 of 10

    • Avaliação de peptídeos sintéticos selecionados por phage display para o sorodiagnóstico da Paracoccidioidomicose 

      Portes, Leticia da Silva [UNIFESP] (Universidade Federal de São Paulo, 2017-06-29)
      Paraccocidioidomycosis (PCM) is a systemic granulomatous disease caused by the thermo-dimorphic fungus from complex Paraccocidioides. The disease diagnosis uses both direct detection of the fungus in biological samples and ...

    • Caracterização de marcadores de virulência em Paracoccidioides brasiliensis 

      Kioshima, Érika Seki [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2009-06-24)
      Paracoccidioidomycosis (PCM) is a human systemic granulomatous disease, prevalent in South America, caused by a thermodimorphic fungus, Paracoccidioides brasiliensis. This fungus presents complex antigenic structure and ...

    • Efeito do peptídeo ligante de heparam sulfato na progressão tumoral 

      Melo, Carina Mucciolo [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2018-02-22)
      Heparan sulfate (HS) is widely distributed and evolutionarily conserved, a fact that dates back to the vital importance of this molecule in cell development and functions such as cell proliferation, migration, adhesion, ...

    • Lepstospira interrogans shotgun phage display identified LigB as a heparin-binding protein 

      Ching Ching, Ana Tung; Favaro, Regiane Degan; Lima, Swiany Silveira; Muniz Chaves, Agtha de Alencar; Lima, Marcelo Andrade de [UNIFESP]; Nader, Helena Bonciani [UNIFESP]; Estima Abreu, Patricia A.; Ho, Paulo Lee (Elsevier B.V., 2012-11-02)
      LigB is an adhesin from pathogenic Leptospira that is able to bind to extracellular matrix and is considered a virulence factor. A shotgun phage display genomic library was constructed and used for panning against Heparan ...

    • A novel melanoma-targeting peptide screened by phage display exhibits antitumor activity 

      Matsuo, Alisson L. [UNIFESP]; Tanaka, Aparecida S. [UNIFESP]; Juliano, Maria A. [UNIFESP]; Rodrigues, Elaine G. [UNIFESP]; Travassos, Luiz R. [UNIFESP] (Springer, 2010-12-01)
      Peptide display on the phage surface has been widely used to identify specific peptides targeting several in vivo and in vitro tumor cells and the tumor vasculature, playing a role in the discovery of bioactive antitumor ...

    • Prokineticin receptor identified by phage display is an entry receptor for Trypanosoma cruzi into mammalian cells 

      Khusal, Ketna Guilhermino; Tonelli, Renata Rosito [UNIFESP]; Mattos, Eliciane Cevolani; Soares, Chrislaine Oliveira; Di Genova, Bruno Martorelli [UNIFESP]; Juliano, Maria Aparecida [UNIFESP]; Urias, Úrsula; Colli, Walter; Alves, Maria Julia Manso (Springer, 2015-01-01)
      Trypanosoma cruzi trypomastigotes invade a great variety of mammalian cells, with several molecules being implicated in this complex event. Herein, the sequence GGIALAG present in prokineticin-2 receptor (PKR2), selected ...

    • Selective inhibitors of digestive enzymes from Aedes aegypti larvae identified by phage display 

      Soares, Tatiane Sanches [UNIFESP]; Soares Torquato, Ricardo Jose [UNIFESP]; Alves Lemos, Francisco Jose; Tanaka, Aparecida Sadae [UNIFESP] (Elsevier B.V., 2013-01-01)
      Dengue is a serious disease transmitted by the mosquito Aedes aegypti during blood meal feeding. It is estimated that the dengue virus is transmitted to millions of individuals each year in tropical and subtropical areas. ...

    • Subtractive phage display selection for screening and identification of peptide sequences with potential use in serodiagnosis of paracoccidioidomycosis caused by Paracoccidioides brasiliensis 

      Portes, Leticia da Silva [UNIFESP]; Kioshima, Érika Seki; Camargo, Zoilo Pires de [UNIFESP]; Batista, Wagner Luiz [UNIFESP]; Xander, Patricia [UNIFESP] (Wiley, 2017)
      Paracoccidioidomycosis (PCM) is a systemic granulomatous disease endemic in Latin America whose aetiologic agents are the thermodimorphic fungi Paracoccidioides brasiliensis and Paracoccidioides lutzii. Despite technological ...

    • Synthetic Peptides Mimic gp75 from Paracoccidioides brasiliensis in the Diagnosis of Paracoccidioidomycosis 

      Caldini, Camila Pistelli [UNIFESP]; Xander, Patricia [UNIFESP]; Kioshima, Érika Seki [UNIFESP]; Bachi, Andre Luis Lacerda [UNIFESP]; Camargo, Zoilo Pires de [UNIFESP]; Mariano, Mario [UNIFESP]; Lopes, Jose Daniel [UNIFESP] (Springer, 2012-07-01)
      Paracoccidioidomycosis (PCM) is a systemic granulomatous disease, endemic in Latin America, caused by the thermal dimorphic fungus Paracoccidioides brasiliensis. Although some fungal antigens have already been characterized ...

    • Validation of a Phage Display Method for Protease Inhibitor Selection Using SFTI and HiTI Synthetic Hybrid Peptides 

      Marco, Renato de [UNIFESP]; Azzolini, Simone Sant'Anna [UNIFESP]; Lovato, Diogo Ventura [UNIFESP]; Torquato, Ricardo Jose Soares [UNIFESP]; Amino, Rogerio [UNIFESP]; Miranda, Antonio de [UNIFESP]; Tanaka, Aparecida Sadae [UNIFESP] (Bentham Science Publ Ltd, 2010-11-01)
      A recombinant Haematobia irritans irritans trypsin inhibitor (HiTI - Mw 7030 kDa) phagemid library was constructed and displayed functionally on the tip of the filamentous M13 phage. A combinatorial library of 7.2 x 10(6) ...