Browsing by Subject "Pentoxifylline"

Now showing items 1-10 of 14

    • Aspectos histomorfológicos e respiratórios em modelo de lesão pulmonar aguda por sepse em ratos tratados com pentoxifilina 

      Oliveira, Wagner Rogerio Souza de [UNIFESP]; Cavassani, Sâmia Santos [UNIFESP]; Maganhin, Carla Cristina [UNIFESP]; Carbonel, Adriana Aparecida Ferraz [UNIFESP]; Simões, Manuel de Jesus [UNIFESP]; Simões, Ricardo Santos [UNIFESP]; Junqueira, Virginia Berlanga Campos [UNIFESP]; Oliveira-Júnior, Itamar Souza [UNIFESP] (Associação Médica Brasileira, 2009-01-01)
      OBJECTIVE: Respiratory repercussion on acute lung injury in a model of induced sepsis intraperitoneally. METHODS: Fifteen animals taken at random were submitted to adult male Wistar rats. The rats were randomly divided ...

    • A comparative study of pentoxifylline effects in adult and aged rats submitted to lung dysfunction by thermal injury 

      Ramallo, Bianca Trovello [UNIFESP]; Lourenço, Elizete [UNIFESP]; Cruz, Renata Harumi [UNIFESP]; Almeida, Jacqueline Camargo [UNIFESP]; Taha, Murched Omar [UNIFESP]; Silva, Priscilla Yuri Okochi Alves [UNIFESP]; Oliveira-Júnior, Itamar Souza [UNIFESP] (Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2013-02-01)
      PURPOSE: To investigate the protective effects of pentoxifylline against lung injury observed after dorsal scald in aged animals. METHODS: Adult (eight months old) and aged (20 months old) rats were subjected to thermal ...

    • Effect of pentoxifylline on lung inflammation and gas exchange in a sepsis-induced acute lung injury model 

      Oliveira-Júnior, Itamar Souza [UNIFESP]; Brunialti, Milena Karina Coló [UNIFESP]; Koh, Ivan Hong Jun [UNIFESP]; Junqueira, Virginia Berlanga Campos [UNIFESP]; Salomão, Reinaldo [UNIFESP] (Associação Brasileira de Divulgação Científica, 2006-11-01)
      Experimental models of sepsis-induced pulmonary alterations are important for the study of pathogenesis and for potential intervention therapies. The objective of the present study was to characterize lung dysfunction (low ...

    • The effects of pentoxifylline into the kidneys of rats in a model of unilateral hindlimb ischemia/reperfusion injury 

      Teruya, Roberto; Fagundes, Djalma José [UNIFESP]; Oshima, Celina Tizuko Fujiyama [UNIFESP]; Brasileiro, José Lacerda; Marks, Guido; Ynouye, Celso Massachi; Simões, Manuel de Jesus [UNIFESP] (Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2008-02-01)
      PURPOSE: To study the role of pentoxifylline (PTX) on remote kidney injury caused by muscle ischemia of left hindlimb of rats. METHODS: After xylazine and ketamine anesthesia, the left hindlimb of rats (n=66) were submitted ...

    • Effects of Pentoxifylline on Inflammation and Lung Dysfunction in Ventilated Septic Animals 

      Oliveira-Junior, Itamar Souza [UNIFESP]; Souza Oliveira, Wagner Rogerio [UNIFESP]; Cavassani, Samia Santos [UNIFESP]; Colo Brunialti, Milena Karina; Salomao, Reinaldo [UNIFESP] (Lippincott Williams & Wilkins, 2010-04-01)
      Acute respiratory distress syndrome secondary to sepsis is associated with high morbidity and mortality. the purpose of this study was to characterize the effects of ventilatory strategy and the modulating activity of ...

    • Effects of pentoxifylline treatment before freezing on motility, viability and acrosome status of poor quality human spermatozoa cryopreserved by the liquid nitrogen vapor method 

      Esteves, Sandro Cassiano [UNIFESP]; Spaine, Deborah Montagnini [UNIFESP]; Cedenho, Agnaldo Pereira [UNIFESP] (Associação Brasileira de Divulgação Científica, 2007-07-01)
      The objective of the present study was to investigate the effects of the direct addition of pentoxifylline (PF) to the ejaculates of men with poor sperm quality before freezing on post-thaw sperm motility, viability, ...

    • Estudo de aspectos morfológicos e funcionais de ratos submetidos a isquemia e repercussão de músculo esquelético, sob a ação da pentoxifilina 

      Teruya, Roberto [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2006)
      Objetivos: estudar os aspectos morfológicos e funcionais do rim de ratos relacionados com a isquemia e reperfusão de musculatura esquelética e o uso da pentoxifilina. Métodos: Ratos Wistar EPM-I (n=60) foram submetidos à ...

    • The expression of endothelial and inducible nitric oxide synthase and apoptosis in intestinal ischemia and reperfusion injury under the action of ischemic preconditioning and pentoxifylline 

      Ribeiro de Oliveira, Teresinha Regina; de Oliveira, Geraldo Ferreira; Simoes, Ricardo Santos; Feitosa, Suellen Maurim [UNIFESP]; Tikazawa, Eduardo Hiroshi; Monteiro, Hugo Pequeno [UNIFESP]; Fagundes, Djalma Jose [UNIFESP]; Taha, Murched Omar [UNIFESP] (Acta Cirurgica Brasileira, 2017)
      Purpose: To investigate the expression of nitric oxide synthase (NOS) and apoptosis associated with ischemic preconditioning (IPC) and pentoxifylline (PTX) in intestinal ischemia (I) and reperfusion (R) injury. Methods: ...

    • Histological modification in TRAM flap in rats treated with pentoxifylline 

      Lucca, Audrien Furlan de; Brasolin, Adriano Guimarães; Feitosa, Roney Gonçalves Fechine; Enokihara, Milvia Maria Simões e Silva; Gomes, Heitor Francisco de Carvalho; Ferreira, Lydia Masako [UNIFESP] (Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2014-01-01)
      PURPOSE: To investigate the blood vessels' concentration in TRAM flap's rat model, in the presence of pentoxifylline.METHODS:32 male, Wistar-EPM rats were divided into two groups. Control group (C): 0.5 ml of saline, ...

    • Pentoxifylline associated to hypertonic saline solution attenuates inflammatory process and apoptosis after intestinal ischemia/reperfusion in rats 

      Marques, Geraldo Magela Nogueira; Rasslan, Roberto; Belon, Alessandro Rodrigo; Carvalho, Juliana Gonçalves; Felice Neto, Raphael; Rasslan, Samir; Utiyama, Edivaldo Massazo; Montero, Edna Frasson de Souza [UNIFESP] (Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2014-11-01)
      PURPOSE:To evaluate intestinal inflammatory and apoptotic processes after intestinal ischemia/reperfusion injury, modulated by pentoxifylline and hypertonic saline.METHODS:It was allocated into four groups (n=6), 24 male ...