Browsing by Subject "Parkinson's disease"
Now showing items 1-10 of 68
-
Acoustic voice assessment in Parkinson's disease patients submitted to posteroventral pallidotomy
(Academia Brasileira de Neurologia - ABNEURO, 2005-03-01)Long-term complications in levodopa treated Parkinson's disease (PD) patients caused a resurgence of interest in pallidotomy as an option of treatment. However, postoperative complications such as speech disorders can ...
-
Association of a neuronal nitric oxide synthase gene polymorphism with levodopa-induced dyskinesia in Parkinson's disease
(Academic Press Inc Elsevier Science, 2018)Background: Levodopa-induced dyskinesia (LID) is a common complication of advanced Parkinson's disease (PD). PD physiopathology is associated with dopaminergic and non-dopaminergic pathways, including the nitric oxide ...
-
Attenuation of motor deficits by hydroethanolic extract of Poincianella pyramidalis in a Parkinson's disease model
(Univ Santiago Chile Casa, 2017)The present study aimed to evaluate the possible neuroprotective effect of the hydroethanolic extract of Poincianella pyramidalis (EFIPp) (Tul.) L. P. Queiroz (Fabaceae), an endemic plant found in Northeastern Brazil, ...
-
Avaliação do processamento auditivo de sons não-verbais em indivíduos com doença de Parkinson
(ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, 2004-08-01)Auditory processing, as we understand, refers to how the individual handles with auditory information. The importance of auditory perception of sound sequences and temporal patterns in acquiring and comprehending symbolic ...
-
Avaliação dos parâmetros cardiovasculares no modelo da Doença de Parkinson induzido pela 6-hidroxidopamina (6-OHDA) e tratados com domperidona
(Universidade Federal de São Paulo (UNIFESP), 2019-11-21)Após a doença de Alzheimer, a doença de Parkinson (DP) é a segunda doença neurológica degenerativa progressiva mais frequente. Afeta tanto o sistema nervoso central quanto o sistema nervoso autônomo de maneira variável. ...
-
Average annual cost of Parkinson's disease in Sao Paulo, Brazil, with a focus on disease-related motor symptoms
(Dove Medical Press Ltd, 2017)Background: Although Parkinson's disease is the second most prevalent neurodegenerative disease worldwide, its cost in Brazil - South America's largest country - is unknown. Objective: The goal of this study was to calculate ...
-
Behavioural and neurochemical effects of phosphatidylserine in MPTP lesion of the substantia nigra of rats
(Elsevier B.V., 2004-01-26)The present study investigated the effects of intranigral MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) infusion on rats treated with phosphatidylserine and evaluated in two memory tasks and on striatal dopamine ...
-
Caffeine neuroprotective effects on 6-OHDA-lesioned rats are mediated by several factors, including pro-inflammatory cytokines and histone deacetylase inhibitions
(Elsevier B.V., 2014-05-01)Several lines of evidences have shown the inversion association between coffee consumption and Parkinson's disease (PD) development. Caffeine is a methylxanthine known as a non-selective inhibitor of A2A and A1 adenosine ...
-
Cannabidiol as a Promising Strategy to Treat and Prevent Movement Disorders?
(Frontiers Media Sa, 2018)Movement disorders such as Parkinson's disease and dyskinesia are highly debilitating conditions linked to oxidative stress and neurodegeneration. When available, the pharmacological therapies for these disorders are still ...
-
Cannabidiol Prevents Motor and Cognitive Impairments Induced by Reserpine in Rats
(Frontiers Media Sa, 2016)Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that presents antipsychotic, anxiolytic, anti-inflammatory, and neuroprotective effects. In Parkinson's disease patients, CBD is able to attenuate ...