Now showing items 1-10 of 12

    • Avaliação Dos Efeitos Da Hiperglicemia Materna Sobre A Sinalização Hipotalâmica Na Vida Adulta Da Prole 

      Araujo, Aline Duarte De [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2017-11-30)
      Diabetes mellitus during pregnancy results in alterations in glucose homeostasis and in the hypothalamic function involved in the regulation of energetic metabolism in the offspring. Epidemiological studies have shown an ...

    • Delayed physical and neurobehavioral development and increased aggressive and depression-like behaviors in the rat offspring of dams fed a high-fat diet 

      Giriko, Catherine Assuka [UNIFESP]; Andreoli, Carla Albuquerque [UNIFESP]; Mennitti, Lais Vales [UNIFESP]; Hosoume, Lilian Fazion [UNIFESP]; Souto, Tayane dos Santos [UNIFESP]; Silva, Alexandre Valotta da [UNIFESP]; Mendes-da-Silva, Cristiano [UNIFESP] (Elsevier B.V., 2013-12-01)
      Early maternal exposure to a high-fat diet (HFD) may influence the brain development of rat offspring and consequently affect physiology and behavior. Thus, in the present study, we investigated the somatic, physical, ...

    • Dieta hiperlipídica materna e administração de ácido graxo palmitato: estudo in vivo do hipocampo da prole de camundongos e in vitro em culturas de neuroblastos e micróglias de proteínas das vias da serotonina e/ou inflamação e do fator neurotrófico BDNF 

      Dias, Clarissa Tavares [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2019-03-21)
      Introduction: Maternal high-fat diet (HFD) consumption promotes a systemic inflammatory condition that may impair the offspring brain development, damaging memory and learning once it reaches the hippocampus. In vitro ...

    • Effects of branched-chain amino acid (BCAA) supplementation on endurance exercise performance of pregnant rats 

      Monteiro, G. A. [UNIFESP]; Aoki, M. S.; Santos, C. B. [UNIFESP]; Monteiro, A. G. [UNIFESP]; Russo, A. [UNIFESP]; Piçarro, Ivan da Cruz [UNIFESP] (Elsevier B.V., 2009-04-01)
      Aims. - the present study evaluated the effects of BCAA supplementation on exercise performance of pregnant rats.Methods. - in order to assess these effects, Wistar rats were divided into four groups: sedentary not-supplemented ...

    • Estudo do disco epifisário de camundongos fêmeas lactantes com hiperprolactinemia e seus filhotes 

      Araujo Junior, Osvaldo Pereira [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2020-01-30)
      Objective: To evaluate the epiphyseal plate growing (EPG) of offspring de lactating mice with hiperprolactinemia induce by metoclopramida. Materials and Methods: For this purpose, 20 adult female mice were divided into 2 ...

    • Lifetime psychopathology among the offspring of Bipolar I parents 

      Zappitelli, Marcelo Cardoso [UNIFESP]; Bordin, Isabel Altenfelder Santos [UNIFESP]; Hatch, John P.; Caetano, Sheila Cavalcante [UNIFESP]; Zunta-Soares, Giovana; Olvera, Rene L.; Soares, Jair C. (Faculdade de Medicina / USP, 2011-01-01)
      BACKGROUND: Recent studies have demonstrated high rates of psychopathology in the offspring of parents with bipolar disorder. The aim of this study was to identify psychiatric diagnoses in a sample of children of bipolar ...

    • Maternal seizures can affect the brain developing of offspring 

      Cossa, Ana Carolina [UNIFESP]; Lima, Daiana Correia [UNIFESP]; do Vale, Tiago Gurgel; Alves de Alencar Rocha, Anna Karynna [UNIFESP]; Naffah-Mazzacoratti, Maria da Graca [UNIFESP]; da Silva Fernandes, Maria Jose [UNIFESP]; Amado, Debora [UNIFESP] (Springer/Plenum Publishers, 2016)
      To elucidate the impact of maternal seizures in the developing rat brain, pregnant Wistar rats were subjected to the pilocarpine-induced seizures and pups from different litters were studied at different ages. In the first ...

    • Preserved white matter in unmedicated pediatric bipolar disorder 

      Teixeira, Ana Maria Aristimunho; Kleinman, Ana; Zanetti, Marcus; Jackowski, Marcel [UNIFESP]; Duran, Fábio Luís de Souza; Pereira, Fabricio; Lafer, Beny; Busatto Filho, Geraldo [UNIFESP]; Caetano, Sheila Cavalcante (Elsevier B.V., 2014-09-05)
      White matter (WM) abnormalities have been reported in bipolar disorder (BD) patients, as well as in their non-BD relatives, both children and adults. Although it is considered an emerging vulnerability marker for BD, there ...

    • Quality of life in youth with bipolar disorder and unaffected offspring of parents with bipolar disorder 

      Gomes, Bernardo C.; Kleinman, Ana; Carvalho, Andrea Ferrari; Pereira, Tatiana Couto F.; Gurgel, Ana Paola; Lafer, Beny; Busatto, Geraldo F.; Caetano, Sheila C. [UNIFESP]; de Almeida Rocca, Cristiana Castanho (Elsevier Science Bv, 2016)
      Background: There have been few studies investigating quality of life (QoL) in pediatric bipolar disorder (BD) patients and none comparing it with that observed in unaffected offspring of parents with BD and healthy controls. ...

    • Swimming of pregnant rats at different water temperatures 

      Osorio, Rodrigo Alexis Lazo [UNIFESP]; Silveira, Vera Lucia Flor [UNIFESP]; Maldjian, S. [UNIFESP]; Morales Junior, A. [UNIFESP]; Christofani, Junia Scarlatelli [UNIFESP]; Russo, Adriana Kowalesky [UNIFESP]; Silva, Antonio Carlos da [UNIFESP]; Piçarro, Ivan da Cruz [UNIFESP] (Elsevier B.V., 2003-08-01)
      We studied the chronic effect of exercise during water immersion, associated with thermal stress (water temperature at 22, 35 and 40 degreesC) at an intensity of 80% of maximal work load supported in pregnant rats (P) and ...