Browsing by Subject "Nociception"

Now showing items 1-7 of 7

    • Kinin and opioid receptors in the paratrigeminal nucleus modulate the somatosensory reflex to rat sciatic nerve stimulation 

      Koepp, Janice; Caous, Cristofer André [UNIFESP]; Rae, Giles Alexander; Balan, Antonio Claudir [UNIFESP]; Lindsey, Charles Julian [UNIFESP] (Elsevier B.V., 2005-08-01)
      The influence of kinin and opioid receptor blockade in the paratrigeminal nucleus (Pa5) on the somatosensory reflex (SSR) to sciatic nerve stimulation (SNS) was assessed in anaesthetized-paralyzed rats. SNS (square 1 ms ...

    • Kininogenase activity of Thalassophryne nattereri fish venom 

      Lopes-Ferreira, M.; Emim, JADS; Oliveira, V; Puzer, L.; Cezari, M. H.; Araujo, MDS; Juliano, L.; Lapa, A. J.; Souccar, C.; Silva, AMMA (Elsevier B.V., 2004-12-01)
      Accidents caused by the venomous fish Thalassophryne nattereri are characterized by edema, intense pain and necrosis at the site of the sting. This study assessed the nociceptive and edematogenic activities of T nattereri ...

    • Long-term gender behavioral vulnerability after nociceptive neonatal formalin stimulation in rats 

      Negrigo, Aline [UNIFESP]; Medeiros, Magda; Guinsburg, Ruth [UNIFESP]; Covolan, Luciene [UNIFESP] (Elsevier B.V., 2011-03-03)
      The role of sex and gender in accounting for individual pain behaviors is poorly understood. the present study was conducted to determine whether neonatal nociceptive stimuli at postnatal day 1 (PD1) in rats would lead to ...

    • Role of the paratrigeminal nucleus in nocifensive responses of rats to chemical, thermal and mechanical stimuli applied to the hind paw 

      Koepp, Janice; Lindsey, Charles Julian [UNIFESP]; Motta, Emerson Marcelo; Rae, Giles Alexander (Elsevier B.V., 2006-06-01)
      Anatomical and immunohystochemical data suggest the paratrigeminal nucleus (Pa5) may play a role in nociceptive processing. the current study examines the influence of unilateral Pa5 lesion on nocifensive responses of ...

    • The role of the paratrigeminal nucleus in the pressor response to sciatic nerve stimulation in the rat 

      Caous, Cristofer André [UNIFESP]; Koepp, Janice; Couture, Rejean; Balan, Antonio Claudir [UNIFESP]; Lindsey, Charles Julian [UNIFESP] (Elsevier B.V., 2008-06-01)
      The paratrigeminal nucleus (Pa5), an input site for spinal, trigeminal, vagus and glossopharyngeal afferents, is a recognized site for orofacial nociceptive sensory processing. It has efferent connections to brain structures ...

    • Sex-related long-term behavioral and hippocampal cellular alterations after nociceptive stimulation throughout postnatal development in rats 

      Lima, Marcia [UNIFESP]; Malheiros, Jackeline [UNIFESP]; Negrigo, Aline [UNIFESP]; Tescarollo, Fabio [UNIFESP]; Medeiros, Magda; Suchecki, Deborah [UNIFESP]; Tannus, Alberto; Guinsburg, Ruth [UNIFESP]; Covolan, Luciene [UNIFESP] (Elsevier B.V., 2014-02-01)
      Early noxious stimuli may alter the neurogenesis rate in the dentate gyrus and the behavioral repertoire of adult rats. This study evaluated the long-term effects of noxious stimulation, imposed in different phases of ...

    • Valproic acid: an anticonvulsant drug with potent antinociceptive and anti-inflammatory properties 

      Machado Ximenes, Jose Christian [UNIFESP]; Goncalves, Danilo de Oliveira; Pinheiro Siqueira, Rafaelly Maria; Tavares Neves, Kelly Rose; Cerqueira, Gilberto Santos; Correia, Alyne Oliveira; Cavalcante Felix, Francisco Helder; Almeida Moreira Leal, Luzia Kalyne; Castro Brito, Gerly Anne de; Naffah-Mazzacorati, Maria da Graca [UNIFESP]; Barros Viana, Glauce Socorro de (Springer, 2013-07-01)
      Valproic acid (VA) is a major antiepileptic drug, used for several therapeutic indications. It has a wide activity spectrum, reflecting on mechanisms of action that are not fully understood. the objectives of this work ...