Browsing by Subject "Nitric oxide"

Ascorbic acid reduces gentamicin-induced nephrotoxicity in rats through the control of reactive oxygen species

Moreira, Miriam A.; Nascimento, Marcos A.; Bozzo, Tatiana A.; Cintra, Alvaro [UNIFESP]; Silva, Sonia M. da [UNIFESP]; Dalboni, Maria Aparecida [UNIFESP]; Mouro, Margaret G.; Higa, Elisa M. S. [UNIFESP] (Churchill Livingstone, 2014-04-01)

Background & aim: Oxidative stress has been implicated in the pathophysiology of many forms of acute renal failure. the aim was examine the effect of vitamin C on oxidative stress and its relationship with nitric oxide on ...

Association of a neuronal nitric oxide synthase gene polymorphism with levodopa-induced dyskinesia in Parkinson's disease

Santos-Lobato, Bruno Lopes; Borges, Vanderci [UNIFESP]; Ferraz, Henrique Ballalai [UNIFESP]; Mata, Ignacio Fernandez; Zabetian, Cyrus P.; Tumas, Vitor (Academic Press Inc Elsevier Science, 2018)

Background: Levodopa-induced dyskinesia (LID) is a common complication of advanced Parkinson's disease (PD). PD physiopathology is associated with dopaminergic and non-dopaminergic pathways, including the nitric oxide ...

Bj-PRO-5a, a natural angiotensin-converting enzyme inhibitor, promotes vasodilatation mediated by both bradykinin B-2 and M1 muscarinic acetylcholine receptors

Morais, Katia Luciano Pereira [UNIFESP]; Hayashi, Mirian Akemi Furuie [UNIFESP]; Bruni, F. M.; Lopes-Ferreira, M.; Camargo, Antonio Carlos Martins de [UNIFESP]; Ulrich, H.; Lameu, C. (Elsevier B.V., 2011-03-15)

Bradykinin-potentiating peptides (BPPs) or proline-rich oligopeptides (PROs) isolated from the venom glands of Bothrops jararaca (Bj) were the first natural inhibitors of the angiotensin-converting enzyme (ACE) described. ...

Changes in gene expression in the frontal cortex of rats with pilocarpine-induced status epilepticus after sleep deprivation

Hirotsu, Camila [UNIFESP]; Matos, Gabriela [UNIFESP]; Tufik, Sergio [UNIFESP]; Andersen, Monica Levy [UNIFESP] (Elsevier B.V., 2013-05-01)

Sleep and epilepsy present a bidirectional interaction. Sleep complaints are common in epilepsy, and sleep deprivation may provoke seizures. However, the mechanisms underlying this relationship are unknown. Thus, this study ...

Chronic corticosterone administration facilitates aversive memory retrieval and increases GR/NOS immunoreactivity

Santos, Thays Brenner dos [UNIFESP]; Céspedes, Isabel Cristina [UNIFESP]; Viana, Milena de Barros [UNIFESP] (Elsevier B.V., 2014-07-01)

Glucocorticoids are stress hormones that mediate the organism's reaction to stress. It has been previously proposed that the facilitation of emotional aversive conditioning induced by these hormones may involve nitric ...

A diversidade estrutural de peptídeos potenciadores da bradicinina da Bothrops jararaca (Bj-BPPs) proporciona ações sinérgicas no sistema cardiovascular

Morais, Kátia Luciano Pereira [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2010-03-31)

Our laboratory has shown that one gene codes for the protein precursor that yields the natriuretic peptide type C (CNP) after having been processed, along with a variety of proline-rich peptides, known as bradykinin-potentiating ...

DNA damage and nitric oxide synthesis in experimentally infected balb/c mice with Trypanosoma cruzi

Ribeiro, Daniel Araki [UNIFESP]; Calvi, Sueli A.; Picka, Mariele M.; Persi, Eliana; Carvalho, Thais B. de; Caetano, Priscila K.; Nagoshi, Lidiana R.; Lima, Carlos R. G.; Machado, Jussara Marcondes; Salvadori, Daisy Maria Favero (Elsevier B.V., 2007-07-01)

This study aimed to evaluate whether experimental Chagas disease in acute phase under benznidazole therapy can cause DNA damage in peripheral blood, liver, heart, and spleen cells or induce nitric oxide synthesis in spleen ...