Browsing by Subject "Natural Products"
Now showing items 1-8 of 8
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Attenuation of motor deficits by hydroethanolic extract of Poincianella pyramidalis in a Parkinson's disease model
(Univ Santiago Chile Casa, 2017)The present study aimed to evaluate the possible neuroprotective effect of the hydroethanolic extract of Poincianella pyramidalis (EFIPp) (Tul.) L. P. Queiroz (Fabaceae), an endemic plant found in Northeastern Brazil, ...
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Avaliação do efeito do deidrodieugenol nas alterações inflamatórias e funcionais em sistema nervoso central em camundongos com inflamação crônica de vias aéreas
(Universidade Federal de São Paulo (UNIFESP), 2020-04-06)Asthma is a chronic inflammatory disease of the airways. Allergic asthma associated with the presence of eosinophils is the most common phenotype, however the association of eosinophils with neutrophils characterizes a ...
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Conformational preferences induced by cyclization in orbitides: a vibrational CD study
(Royal Society of Chemistry (RSC), 2022-01-18)Orbitides are bioactive head-to-tail natural cyclic peptides from plant species. Their bioactivity is intrinsically related to the main conformations adopted in solution, whose correct characterization represents an important ...
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Efeito neuroprotetor do extrato etanólico liofilizado de pitanga (Eugenia uniflora L.) em um modelo animal progressivo da Doença de Parkinson
(Universidade Federal de São Paulo, 2023-07-12)A doença de Parkinson (DP) é uma doença neurodegenerativa caracterizada principalmente pela morte dos neurônios dopaminérgicos na Substância Negra parte compacta (SNPc). Sua etiologia ainda não é totalmente esclarecida, ...
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Efeitos da administração crônica do extrato de casca de uva em camundongos submetidos a um modelo progressivo da Doença de Parkinson
(Universidade Federal de São Paulo (UNIFESP), 2020-07-21)Parkinson's disease (PD) is a neurodegenerative disease affecting mainly the elderly population. PD etiology remains unknown, however, evidence shows that genetic predisposition and environmental factors, such as contamination ...
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Efeitos da administração dos extratos de cenoura roxa e preta sobre parâmetros motores, não motores e neuroquímicos em ratos submetidos a um modelo progressivo da Doença de Parkinson
(Universidade Federal de São Paulo, 2020-09-10)Parkinson's disease (PD) is characterized by a loss of dopaminergic neurons in the substantia nigra compact (SNpc). The etiology of PD is unclear and the therapeutic approaches used in PD have been ineffective in ...
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Efeitos de frações isoladas do veneno da formiga dinoponera quadriceps (kempf) em modelo de crises convulsivas induzidas por bicuculina em camundongos
(Universidade Federal de São Paulo (UNIFESP), 2019-02-25)Natural products are recognized as therapeutic tools for treating several diseases since ancient civilizations. In this context, animal venoms and their isolated components have shown great biotechnological potential, ...
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Efeitos neurobiológicos do tratamento com sakuranetina em camundongos.
(Universidade Federal de São Paulo (UNIFESP), 2019-09-27)It is recognized that extracts and substances obtained from natural products, such as plants and animal venom, can contribute to the development of model drugs. The use of medicinal plants for the treatment of various is ...
