Now showing items 1-3 of 3

    • Early Developmental Disruption of Type 2 Deiodinase Pathway in Mouse Skeletal Muscle Does Not Impair Muscle Function 

      Ignacio, Daniele L.; Silvestre, Diego H. S.; Anne-Palmer, Elena; Bocco, Barbara Miranda Leite da Costa [UNIFESP]; Fonseca, Tatiana L.; Ribeiro, Miriam Oliveira; Gereben, Balazs; Bianco, Antonio Carlos; Werneck-de-Castro, João Pedro Saar (Mary Ann Liebert, Inc, 2017)
      Background: Myogenesis is positively regulated by thyroid hormone (triiodothyronine [T3]), which is amplified by the type 2 deiodinase (D2) activation of thyroxine to T3. Global inactivation of the Dio2 gene impairs skeletal ...

    • Efeitos do tratamento com insulina em curto e longo prazo no músculo esquelético de ratos submetidos à lesão térmica 

      Quintana, Hananiah Tardivo [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2018-05-23)
      Burn Injuries (Bi) In Children Are Among The Greatest Epidemiological Problems In The World. Extensive Bi Above 40% Of The Total Body Surface Area Results In Systemic Responses, Such As Insulin Resistance And Increased ...

    • O papel dos receptores B1 e B2 de cininas no reparo do músculo esquelético 

      Silva, Leonardo Martins [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2020-12-18)
      Fibrosis is characterized by an excessive accumulation of extracellular matrix components, being one of the main sequelae acquired after muscle injury. In severe injuries, where healing occurs slowly, fibrosis prevents ...