Browsing by Subject "Mycophenolate mofetil"

Now showing items 1-6 of 6

    • The Challenge of Achieving Target Drug Concentrations in Clinical Trials: Experience From the Symphony Study 

      Ekberg, Henrik; Mamelok, Richard D.; Pearson, Thomas C.; Vincenti, Flavio; Tedesco-Silva, Helio [UNIFESP]; Daloze, Pierre (Lippincott Williams & Wilkins, 2009-05-15)
      Background. the Symphony study compared four immunosuppressant regimens, defined by protocol-specified target drug concentrations. This subanalysis examines actual drug levels and the implications on the interpretation of ...

    • Exploratory calcineurin inhibitor-free regimens in living-related kidney transplant recipients 

      Garcia, Riberto [UNIFESP]; Machado, Paula Goulart Pinheiro [UNIFESP]; Felipe, Claudia Rosso [UNIFESP]; Park, Sung In [UNIFESP]; Spinelli, Glaucio Amaral [UNIFESP]; Franco, Marcello Fabiano de [UNIFESP]; Tedesco-Silva Junior, Hélio [UNIFESP]; Pestana, Jose Osmar Medina [UNIFESP] (Associação Brasileira de Divulgação Científica, 2007-04-01)
      Chronic allograft nephropathy is among the major causes of graft loss even in low-risk kidney transplant recipients and correlates with acute nephrotoxic events during the first year post-transplant. Therefore, calcineurin ...

    • Improved Rejection Prophylaxis With an Initially Intensified Dosing Regimen of Enteric-Coated Mycophenolate Sodium in de Novo Renal Transplant Recipients 

      Budde, Klemens; Tedesco-Silva, Helio [UNIFESP]; Arns, Wolfgang; Shoker, Ahmed; Zeier, Martin; Klinger, Marian; Rosales, Beatriz; Walker, Rowan; Prestele, Hans; Vaidya, Soniya; Kuypers, Dirk (Lippincott Williams & Wilkins, 2011-08-15)
      Background. Approximately half of cyclosporine A-treated renal transplant recipients do not reach sufficient mycophenolic acid (MPA) exposure in the first weeks posttransplantation with standard MPA dosing regimens.Methods. ...

    • Mycophenolate mofetil in children with steroid/cyclophosphamide-resistant nephrotic syndrome 

      Mello, Valderez Raposo de; Rodrigues, Maira Tinte; Mastrocinque, Tais Helena; Laranjo Martins, Simone Paiva; Braga de Andrade, Olberes Vitor; Medeiros Guidoni, Eliana Biondi; Scheffer, Daniel Kashiwamura; Martini Filho, Dino; Toporovski, Julio; Benini, Vanda (Springer, 2010-03-01)
      The purpose of this study was to assess the results of therapy with mycophenolate mofetil (MMF) in children with idiopathic nephrotic syndrome (INS) who were both steroid- and cyclophosphamide-resistant. Treatment lasted ...

    • Mycophenolate Mofetil Initiation in Renal Transplant Patients at Different Times Posttransplantation: the TranCept Switch Study 

      Meier-Kriesche, Herwig-Ulf; Merville, Pierre; Tedesco-Silva, Helio [UNIFESP]; Heemann, Uwe; Kes, Petar; Haller, Hermann; Rostaing, Lionel; Gafner, Nesrin; Bernasconi, Corrado (Lippincott Williams & Wilkins, 2011-05-15)
      Background. Despite evidence of favorable long-term effects of mycophenolate mofetil (MMF) in renal transplantation, its introduction at different times posttransplant has not been studied in large cohorts.Methods. ...

    • Synergistic effect of mycophenolate mofetil and angiotensin-converting enzyme inhibitor in patients with chronic allograft nephropathy 

      Moscoso-Solorzano, G.t. [UNIFESP]; Mastroianni Kirsztajn, Gianna [UNIFESP]; Ozaki, K.s. [UNIFESP]; Franco, Marcello Fabiano de [UNIFESP]; Pacheco-Silva, Alvaro [UNIFESP]; Câmara, Niels Olsen Saraiva [UNIFESP] (Associação Brasileira de Divulgação Científica, 2009-05-01)
      Experimental data and few clinical non-randomized studies have shown that inhibition of the renin-angiotensin system by angiotensin-converting enzyme (ACE) associated or not with the use of mycophenolate mofetil (MMF) could ...