Browsing by Subject "Mitochondria"

Altered mitochondrial function, calcium signaling, and catecholamine release in chromaffin cells of diabetic and SHR rats

Musial, Diego C. [UNIFESP]; Bomfim, Guilherme H. [UNIFESP]; Arranz-Tagarro, Juan A.; Mendez-Lopez, Iago; Miranda-Ferreira, Regiane [UNIFESP]; Jurkiewicz, Aron [UNIFESP]; Jurkiewicz, Neide H. [UNIFESP]; Garcia, Antonio G.; Padin, Juan F. (Elsevier Science Bv, 2017)

Comorbidity of diabetes and hypertension is frequent. Here, we have performed a comparative study in three animal models namely, normotensive Wistar Kyoto (WKY) rats, streptozotocin-induced diabetic rats (STZ), and ...

Baccharis dracunculifolia, the main source of green propolis, exhibits potent antioxidant activity and prevents oxidative mitochondrial damage

Guimaraes, Natalia S. S.; Mello, Joyce C.; Paiva, Juliana S.; Bueno, Paula C. P.; Berretta, Andresa A.; Torquato, Ricardo José Soares [UNIFESP]; Nantes, Iseli L.; Rodrigues, Tiago (Elsevier B.V., 2012-03-01)

Baccharis dracunculifolia DC (Asteraceae) is the main botanical source used by honeybees to produce Brazilian green propolis whose hepatoprotective properties have been already described. in this work we investigated the ...

Bcl-2 Modulates Endoplasmic Reticulum and Mitochondrial Calcium Stores in PC12 Cells

Hirata, Hanako [UNIFESP]; Lopes, Guiomar S. [UNIFESP]; Jurkiewicz, Aron [UNIFESP]; Garcez-do-Carmo, Lucia [UNIFESP]; Smaili, Soraya Soubhi [UNIFESP] (Springer, 2012-02-01)

Endoplasmic reticulum (ER) and mitochondria are intracellular organelles and their interactions are directly involved in different processes such as Ca2+ signaling in cell survival and death mechanisms. Bcl-2 is an ...

Biochemical studies with DNA polymerase beta and DNA polymerase beta-PAK of Trypanosoma cruzi suggest the involvement of these proteins in mitochondrial DNA maintenance

Lopes, Debora de Oliveira; Fonseca Schamber-Reis, Bruno Luiz; Regis-da-Silva, Carlos Gustavo; Rajao, Matheus Andrade; DaRocha, Wanderson Duarte; Macedo, Andrea Mara; Franco, Gloria Regina; Nardelli, Sheila Cristina [UNIFESP]; Schenkman, Sergio [UNIFESP]; Hoffmann, Jean-Sebastein; Cazaux, Christophe; Junho Pena, Sergio Danilo; Ribeiro Teixeira, Santuza Maria; Machado, Carlos Renato (Elsevier B.V., 2008-11-01)

Mammalian DNA polymerase p is a nuclear enzyme involved in the base excision and single-stranded DNA break repair pathways. in trypanosomatids, this protein does not have a defined cellular localization, and its function ...

Caracterização da disfunção mitocondrial no rim de ratos Zucker

Trindade, André Soares [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2017)

Introduction: Obesity is characterized as an inflammatory condition associated to several chronic diseases. Besides promoting cardiovascular, hepatic and renal alterations, adipose tissue accumulation can generate an ...

Complex I spectrophotometric assay in cultured cells: Detailed analysis of key factors

Oliveira, Katia Klug [UNIFESP]; Kiyomoto, Beatriz Hitomi [UNIFESP]; Rodrigues, Andresa De Santi [UNIFESP]; Tengan, Celia Harumi [UNIFESP] (Elsevier B.V., 2013-04-01)

The diagnosis of mitochondrial encephalomyopathies caused by complex I (C-I) deficiency relies mainly on the spectrophotometric C-I assay. Considered difficult, this assay lacks reliability and has high nonspecific activity. ...

Deficiência De Coenzima Q10: Caracterização Clínica, Bioquímica E Molecular

Miyadahira, Juliana Harumi Arita [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2018-11-29)

Objective: To Identify Patients With Suspected Coenzyme Q10 Deficiency (Coq10) And Make A Clinical, Biochemical And Molecular Characterization Of These Patients. Methods: Twenty Seven Patients Between 0 And 17 Years Old ...

Deleções do DNA mitocondrial no envelhecimento: efeito da disfunção na fosforilação oxidativa

Tengan, Celia Harumi [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 1997)

O efeito do tratamento com carnosina durante o processamento seminal de amotras humanas por gradiente de densidade descontínuo

Adami, Luana Nayara Gallego [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2018-02-27)

Introduction: Male infertility can be caused by seminal oxidative stress that lead to sperm damages. However, seminal plasma contains antioxidants mechanisms responsible for avoiding these cellular damages. On the other ...

Efeito do treinamento físico de natação nos ratos espontaneamente hipertensos (SHR) antes, durante e após o desenvolvimento da Hipertensão Arterial

Garcia, Maureen Gabriela Pena [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2019-06-27)

Hypertension is a disease of high prevalence and mortality in the world. Changes in the sympathetic nervous system (SNS) and cellular calcium homeostasis are present in hypertension. In addition, a link was also established ...