Now showing items 1-5 of 5

    • Characterization of a novel cystatin type 2 from Rhipicephalus microplus midgut 

      Cardoso, Thyago H. S. [UNIFESP]; Lu, Stephen [UNIFESP]; Gonzalez, Boris R. G. [UNIFESP]; Torquato, Ricardo J. S. [UNIFESP]; Tanaka, Aparecida S. [UNIFESP] (Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)
      The Rhipicephalus (Boophilus) microplus is an exclusive bovine ectoparasite responsible for the transmission of pathogens that decrease meat, leather and milk productions. Cattle vaccination is an alternative to control ...

    • Characterization of thrombin inhibitory mechanism of rAaTI, a Kazal-type inhibitor from Aedes aegypti with anticoagulant activity 

      Watanabe, Renata Midori Okuta [UNIFESP]; Tanaka-Azevedo, Anita M.; Araujo, Mariana da Silva [UNIFESP]; Juliano, Maria Aparecida [UNIFESP]; Tanaka, Aparecida Sadae [UNIFESP] (Elsevier B.V., 2011-03-01)
      Saliva of blood-sucking arthropods contains a complex mixture of anti-haemostatic, anti-inflammatory and immune-modulator compounds. Among anti-haemostatic factors, there are anticoagulants, vasodilators and platelet ...

    • Influence of the intestinal anticoagulant in the feeding performance of triatomine bugs (Hemiptera; Reduviidae) 

      Paim, Rafaela M. M.; Araujo, Ricardo N.; Soares, Adriana C.; Dhom Lemos, Lucas C.; Tanaka, Aparecida S. [UNIFESP]; Gontijo, Nelder F.; Lehane, Michael J.; Pereira, Marcos H. (Elsevier B.V., 2011-06-01)
      Triatomines are haematophagous insects in all post-embryonic life stages. They are vectors of Ttypanosoma cruzi, the causative agent of Chagas disease. Their vectorial ability is influenced by their feeding performance, ...

    • A new antimicrobial protein from the anterior midgut of Triatoma infestans mediates Trypanosoma cruzi establishment by controlling the microbiota 

      Buarque, Diego de Souza [UNIFESP]; Gomes, Cicera M. [UNIFESP]; Araujo, Ricardo N.; Pereira, Marcos H.; Ferreira, Roberta C.; Guarneri, Alessandra A.; Tanaka, Aparecida Sadae [UNIFESP] (Elsevier France-Editions Scientifiques Medicales Elsevier, 2016)
      The Reduviid Triatoma infestans is a vector for the protozoan Trypanosoma cruzi, the etiological agent of Chagas disease. The parasite must address the defense molecules and microbiota that colonize the anterior midgut of ...

    • A novel trypsin Kazal-type inhibitor from Aedes aegypti with thrombin coagulant inhibitory activity 

      Watanabe, Renata M. O. [UNIFESP]; Soares, Tatiane S. [UNIFESP]; Morais-Zani, Karen; Tanaka-Azevedo, Anita M.; Maciel, Ceres; Capurro, Margareth L.; Torquato, Ricardo J. S. [UNIFESP]; Tanaka, Aparecida S. [UNIFESP] (Elsevier B.V., 2010-08-01)
      Kazal-type inhibitors play several important roles in invertebrates, such as anticoagulant, vasodilator and antimicrobial activities. Putative Kazal-type inhibitors were described in several insect transcriptomes. in this ...