Now showing items 1-10 of 92

    • Acute buspirone abolishes the expression of behavioral dopaminergic supersensitivity in mice 

      Queiroz, Claudio Marcos Teixeira de [UNIFESP]; Alcântara, F.b. [UNIFESP]; Yagüe, A.m.l. [UNIFESP]; Bibancos, Theo [UNIFESP]; Frussa-Filho, Roberto [UNIFESP] (Associação Brasileira de Divulgação Científica, 2002-02-01)
      Previous studies have shown that rats withdrawn from long-term treatment with dopamine receptor blockers exhibit dopaminergic supersensitivity, which can be behaviorally evaluated by enhanced general activity observed in ...

    • Acute total sleep deprivation potentiates amphetamine-induced locomotor-stimulant effects and behavioral sensitization in mice 

      Saito, Luis P. [UNIFESP]; Fukushiro, Daniela F. [UNIFESP]; Hollais, Andre W. [UNIFESP]; Mari-Kawamoto, Elisa [UNIFESP]; Costa, Jacqueline M. [UNIFESP]; Berro, Lais F. [UNIFESP]; Aramini, Tatiana C. F. [UNIFESP]; Wuo-Silva, Raphael [UNIFESP]; Andersen, Monica L. [UNIFESP]; Tufik, Sergio [UNIFESP]; Frussa-Filho, Roberto [UNIFESP] (Elsevier B.V., 2014-02-01)
      It has been demonstrated that a prolonged period (48 h) of paradoxical sleep deprivation (PSD) potentiates amphetamine (AMP)-induced behavioral sensitization, an animal model of addiction-related neuroadaptations. in the ...

    • Adolescent mice are more vulnerable than adults to single injection-induced behavioral sensitization to amphetamine 

      Kameda, Sonia Regina [UNIFESP]; Fukushiro, Daniela Fukue [UNIFESP]; Trombin, Thaís Fernanda [UNIFESP]; Procopio-Souza, Roberta [UNIFESP]; Patti, Camilla de Lima [UNIFESP]; Hollais, André Willian [UNIFESP]; Calzavara, Mariana Bendlin [UNIFESP]; Abílio, Vanessa Costhek [UNIFESP]; Ribeiro, Rosana de Alencar [UNIFESP]; Tufik, Sergio [UNIFESP]; D'Almeida, Vânia [UNIFESP]; Frussa Filho, Roberto [UNIFESP] (Elsevier B.V., 2011-04-01)
      Drug-induced behavioral sensitization in rodents has enhanced our understanding of why drugs acquire increasing motivational and incentive value. Compared to adults, human adolescents have accelerated dependence courses ...

    • Alpha1-adrenergic drugs affect the development and expression of ethanol-induced behavioral sensitization 

      Kim, Andrezza Kyunmi [UNIFESP]; Oliveira Souza-Formigoni, Maria Lucia [UNIFESP] (Elsevier B.V., 2013-11-01)
      Background: According to the incentive sensitization theory, addiction is caused primarily by drug-induced sensitization in the brain mesocorticolimbic systems. After repeated ethanol administration, some animals develop ...

    • Altered cardiomyocyte function and trypanosoma cruzi persistence in chagas disease 

      Cruz, Jader Santos [UNIFESP]; Santos-Miranda, Artur [UNIFESP]; Sales-Junior, Policarpo Ademar [UNIFESP]; Monti-Rocha, Renata [UNIFESP]; Campos, Paula Peixoto [UNIFESP]; Machado, Fabiana Simao [UNIFESP]; Roman-Campos, Danilo [UNIFESP] (Wiley-Blackwell, 2016)
      Chagas disease, caused by the triatominae Trypanosoma cruzi, is one of the leading causes of heart malfunctioning in Latin America. The cardiac phenotype is observed in 20-30% of infected people 10-40 years after their ...

    • Amygdaloid involvement in the defensive behavior of mice exposed to the open elevated plus-maze 

      Sorregotti, Tatiani; Cipriano, Ana Claudia; Cruz, Fabio Cardoso [UNIFESP]; Mascarenhas, Diego Cardozo; Rodgers, Robert John; Nunes-de-Souza, Ricardo Luiz (Elsevier Science Bv, 2018)
      Previous studies have shown that the exposure to an open elevated plus maze (oEPM, an EPM with all four open arms) elicits fear/anxiety-related responses in laboratory rodents. However, very little is known about the ...

    • Análise histomorfométrica no endométrio em modelo ectópico e eutópicos de endometriose em camundongas 

      Silva, Felipe Rosendo da [UNIFESP] (Universidade Federal de São Paulo, 2021-08-26)
      Objetivo: Realizar um modelo de endometriose em camundongos isogênicos Balb/c, implantando tecido endometrial ectópico. Avaliar a histomorfometria dos tecidos endometriais ectópico e eutópicos de camundongo controles e ...

    • Biochemical, biometrical and behavioral changes in male offspring of sleep-deprived mice 

      Aguilar Calegare, Bruno Frederico [UNIFESP]; Fernandes, Leandro [UNIFESP]; Tufik, Sergio [UNIFESP]; D'Almeida, Vania [UNIFESP] (Elsevier B.V., 2010-06-01)
      Epidemiological and experimental studies suggest a high prevalence of cognitive impairment and social behavior deficits in adolescents and adults that have experienced prenatal exposure to adverse conditions. This study ...

    • Caracterização de vesículas extracelulares exportadas pelo fungo 

      Vallejo, Milene Carmes [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2012)
      Este trabalho resultou no estudo de vesículas extracelulares do fungo patogênico Paracoccidioides brasiliensis na fase de levedura. Estas estruturas foram caracterizadas nos isolados Pb3 e Pb18 que pertencem a grupos ...

    • Caracterização experimental do fenômeno de sensibilização comportamental imediata após administração única de diferentes drogas de abuso em camundongos 

      Alvarez, Juliana do Nascimento [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2009-06-24)
      The behavioral sensitization phenomenon is characterized by a progressive and enduring enhancement of the locomotor stimulant effect of drugs of abuse following repeated treatment in rodents. This behavioral phenomenon ...