Browsing by Subject "Matrix metalloproteinases"

Now showing items 1-8 of 8

    • Abnormalities in Metalloproteinase Pathways and IGF-I Axis: A Link Between Birth Weight, Hypertension, and Vascular Damage in Childhood 

      Sesso, Ricardo de Castro Cintra [UNIFESP]; Franco, Maria do Carmo Pinho [UNIFESP] (Nature Publishing Group, 2010-01-01)
      BACKGROUNDAlthough numerous studies suggest an inverse relationship between birth weight and cardiovascular disease, the mechanistic basis of this phenomenon is not fully understood. Here, we postulate that alterations in ...

    • Anti-inflammatory properties of a heparin-like glycosaminoglycan with reduced anti-coagulant activity isolated from a marine shrimp 

      Brito, Adriana S.; Arimateia, Dayse S.; Souza, Lucilla R.; Lima, Marcelo A.; Santos, Vanessa O.; Medeiros, Valquiria P. [UNIFESP]; Ferreira, Paula A.; Silva, Rodrigo A.; Ferreira, Carmen V.; Justo, Giselle Z. [UNIFESP]; Leite, Edda L.; Andrade, Giulianna P. V.; Oliveira, Fernanda W.; Nader, Helena B. [UNIFESP]; Chavante, Suely F. (Elsevier B.V., 2008-11-01)
      The anti-inflammatory properties of a heparin-like compound from the shrimp Litopenaeus vannamei are related. Besides reducing significantly (p < 0.001) the influx of inflammatory cells to injury site in a model of acute ...

    • Contrasting effects of aliskiren versus losartan on hypertensive vascular remodeling 

      Martins-Oliveira, Alisson; Castro, Michele Mazaron de; Oliveira, Diogo Marçal Machado de; Rizzi, Elen; Ceron, Carla Speroni; Guimaraes, Danielle; Reis, Rosana Inacio dos; Costa-Neto, Claudio Miguel; Casarini, Dulce Elena [UNIFESP]; Ribeiro, Amanda Aparecida [UNIFESP]; Gerlach, Raquel Fernanda; Tanus-Santos, Jose Eduardo (Elsevier B.V., 2013-08-20)
      Background: Hyperactivation of the renin-angiotensin system contributes to hypertension-induced upregulation of vascular matrix metalloproteinases (MMPs) and remodeling, especially in the two kidney, one clip (2K1C) ...

    • Effect of photodynamic therapy on the extracellular matrix and associated components 

      Pazos, Marcelo de Castro [UNIFESP]; Nader, Helena Bonciani [UNIFESP] (Associação Brasileira de Divulgação Científica, 2007-08-01)
      In many countries, photodynamic therapy (PDT) has been recognized as a standard treatment for malignant conditions (for example, esophageal and lung cancers) and non-malignant ones such as age-related macular degeneration ...

    • F-18-Fluorodeoxyglucose positron emission tomography and serum cytokines and matrix metalloproteinases in the assessment of disease activity in Takayasu's arteritis 

      Arraes, Anne E. D. [UNIFESP]; de Souza, Alexandre W. S. [UNIFESP]; Mariz, Henrique A. [UNIFESP]; Silva, Neusa P. [UNIFESP]; Torres, Ivone C. G.; Pinto, Paula N. V.; Lima, Eduardo N. P.; Sato, Emilia I. [UNIFESP] (Elsevier Science Inc, 2016)
      Objective: To evaluate F-18-fluorodeoxyglucose (FDG) uptake on positron emission tomography-computed tomography (PET-CT)-and serum levels of different cytokines and matrix metalloproteinases (MMPs) in patients with Takayasu's ...

    • Fibroblast and prostate tumor cell cross-talk: Fibroblast differentiation, TGF-beta, and extracellular matrix down-regulation 

      Coulson-Thomas, Vivien Jane [UNIFESP]; Gesteira, Tarsis F.; Coulson-Thomas, Yvette May [UNIFESP]; Vicente, Carolina M.; Tersariol, Ivarne L. S.; Nader, Helena B.; Toma, Leny (Elsevier B.V., 2010-11-15)
      Growth and survival of tumors at a site of metastasis involve interactions with stromal cells in the surrounding environment. Stromal cells aid tumor cell growth by producing cytokines as well as by modifying the environment ...

    • Nitric oxide modulates metalloproteinase-2, collagen deposition and adhesion rate after polypropylene mesh implantation in the intra-abdominal wall 

      Moretti, Ana I. S.; Souza Pinto, Francisco J. P.; Cury, Vivian; Jurado, Marcia C.; Marcondes, Wagner [UNIFESP]; Velasco, Irineu T.; Souza, Heraldo P. (Elsevier B.V., 2012-01-01)
      Prosthetic meshes are commonly used to correct abdominal wall defects. However, the inflammatory reaction induced by these devices in the peritoneum is not completely understood. We hypothesized that nitric oxide (NO), ...

    • Strategies to prevent hydrolytic degradation of the hybrid layer-A review 

      Tjaderhane, Leo; Nascimento, Fabio D.; Breschi, Lorenzo; Mazzoni, Annalisa; Tersariol, Ivarne L. S. [UNIFESP]; Geraldeli, Saulo; Tezvergil-Mutluay, Arzu; Carrilho, Marcela; Carvalho, Ricardo M.; Tay, Franklin R.; Pashley, David H. (Elsevier B.V., 2013-10-01)
      Objective. Endogenous dentin collagenolytic enzymes, matrix metalloproteinases (MMPs) and cysteine cathepsins, are responsible for the time-dependent hydrolysis of collagen matrix of hybrid layers. As collagen matrix ...