Now showing items 1-10 of 12

    • Antidepressant combination for major depression in incomplete responders-a systematic review 

      Rocha, Fabio Lopes; Fuzikawa, Cintia; Riera, Rachel [UNIFESP]; Ramos, Melissa Guarieiro; Hara, Claudia (Elsevier B.V., 2013-01-10)
      Background: Antidepressant combination has been suggested as a strategy to increase treatment efficacy. the objective of this study was to perform a systematic review and meta-analysis of studies that assessed the effect ...

    • Depressão e hipotireoidismo: uma revisão sistemática 

      Souza, Eduarda Silva [UNIFESP] (Universidade Federal de São Paulo, 2023-01-16)
      A presença de sintomas depressivos em pacientes com hipotireoidismo e a influência da glândula tireoide no humor e nas cognições é bem reconhecida no meio científico e na prática clínica. Nesse contexto, esta revisão ...

    • Evaluation of periodontitis in hospital outpatients with major depressive disorder. A focus on gingival and circulating cytokines 

      de Oliveira Solis, Ana Cristina; Marques, Andrea Horvath; Dominguez, Wagner Vasques; de Almeida Prado, Euthymia Brandao [UNIFESP]; Pannuti, Claudio Mendes; Moreira Lotufo, Roberto Fraga; Lotufo-Neto, Francisco (Academic Press Inc Elsevier Science, 2016)
      An imbalance in stimulated cytokine production is associated with the etiopathogenesis of numerous diseases such as major depressive disorder (MDD) and periodontal disease. Increased cytokine levels have been reported in ...

    • Gene expression in blood of children and adolescents: MOediation between childhood maltreatment and major depressive disorder 

      Spindola, Leticia Maria [UNIFESP]; Pan, Pedro Mario [UNIFESP]; Moretti, Patricia Natalia [UNIFESP]; Ota, Vanessa Kiyomi [UNIFESP]; Santoro, Marcos Leite [UNIFESP]; Cogo-Moreira, Hugo [UNIFESP]; Gadelha, Ary [UNIFESP]; Salum, Giovanni; Manfro, Gisele Gus; Mari, Jair Jesus [UNIFESP]; Brentani, Helena; Grassi-Oliveira, Rodrigo; Brietzke, Elisa [UNIFESP]; Miguel, Euripedes Constantino; Rohde, Luis Augusto; Sato, Joao Ricardo; Bressan, Rodrigo Affonseca [UNIFESP]; Belangero, Sintia Iole [UNIFESP] (Pergamon-Elsevier Science Ltd, 2017)
      Investigating major depressive disorder (MDD) in childhood and adolescence can help reveal the relative contributions of genetic and environmental factors to MDD, since early stages of disease have less influence of illness ...

    • Impact of 5-HTTLPR and BDNF polymorphisms on response to sertraline versus transcranial direct current stimulation: Implications for the serotonergic system 

      Brunoni, A. R.; Kemp, A. H.; Shiozawa, P.; Cordeiro, Q.; Valiengo, L. C. L.; Goulart, A. C.; Coprerski, B. [UNIFESP]; Lotufo, P. A.; Brunoni, D. [UNIFESP]; Perez, A. B. A. [UNIFESP]; Fregni, F.; Bensenor, I. M. (Elsevier B.V., 2013-11-01)
      Transcranial direct current stimulation (tDCS) has been intensively investigated as a non-pharmacological treatment for major depressive disorder (MDD). While many studies have examined the genetic predictors of antidepressant ...

    • Inflamed moods: A review of the interactions between inflammation and mood disorders 

      Rosenblat, Joshua D.; Cha, Danielle S.; Mansur, Rodrigo B. [UNIFESP]; McIntyre, Roger S. (Elsevier B.V., 2014-08-04)
      Mood disorders have been recognized by the World Health Organization (WHO) as the leading cause of disability worldwide. Notwithstanding the established efficacy of conventional mood agents, many treated individuals continue ...

    • Is there a metabolic-mood syndrome? A review of the relationship between obesity and mood disorders 

      Mansur, Rodrigo B. [UNIFESP]; Brietzke, Elisa [UNIFESP]; McIntyre, Roger S. (Elsevier B.V., 2015-05-01)
      Obesity and mood disorders are highly prevalent and co-morbid. Epidemiological studies have highlighted the public health relevance of this association, insofar as both conditions and its co-occurrence are associated with ...

    • Lack of association of indoleamine 2,3-dioxygenase polymorphisms with interferon-alpha-related depression in hepatitis C 

      Almeida, Amanda Cristina Galvão Oliveira de [UNIFESP]; Quarantini, Lucas de Castro [UNIFESP]; Sampaio, Aline Santos [UNIFESP]; Lyra, André Castro; Parise, Carmen Livia [UNIFESP]; Paraná, Raymundo; Oliveira, Irismar Reis de; Koenen, Karestan C; Miranda-Scippa, Ângela Marisa de Aquino [UNIFESP]; Guindalini, Camila [UNIFESP] (Elsevier B.V., 2011-10-01)
      Background: Major depression is a frequent adverse effect of interferon-alpha (IFN-alpha) therapy. Although the indoleamine 2,3-dioxygenase (IDO) enzyme seems to be involved in the pathophysiology of IFN-alpha-induced ...

    • Liraglutide promotes improvements in objective measures of cognitive dysfunction in individuals with mood disorders: A pilot, open-label study 

      Mansur, Rodrigo Barbachan [UNIFESP]; Ahmed, Juhie; Cha, Danielle S.; Woldeyohannes, Hanna O.; Subramaniapillai, Mehala; Lovshin, Julie; Lee, Jung G.; Lee, Jae-Hon; Brietzke, Elisa [UNIFESP]; Reininghaus, Eva Z.; Sim, Kang; Vinberg, Maj; Rasgon, Natalie; Hajek, Tomas; McIntyre, Roger S. (Elsevier Science Bv, 2017)
      Background: There is a paucity of treatments that are capable of reliably and robustly improving cognitive function in adults with mood disorders. Glucagon-like peptide-1 is synthesized centrally and its receptors are ...

    • A randomized, double-blind, placebo-controlled, crossover trial evaluating the effect of intranasal insulin on cognition and mood in individuals with treatment-resistant major depressive disorder 

      Cha, Danielle S.; Best, Michael W.; Bowie, Christopher R.; Gallaugher, Laura Ashley; Woldeyohannes, Hanna O.; Soczynska, Joanna K.; Lewis, Gary; MacQueen, Glenda; Sahakian, Barbara J.; Kennedy, Sidney H.; Lui, Jane P.; Mansur, Rodrigo B. [UNIFESP]; McIntyre, Roger S. (Elsevier Science Bv, 2017)
      Background: Cognitive dysfunction in major depressive disorder (MDD) is identified as a primary therapeutic target