Browsing by Subject "Lipopolysaccharide"

Now showing items 1-10 of 17

    • Adenosine A(2A) receptor agonist (CGS-21680) prevents endotoxin-induced effects on nucleotidase activities in mouse lymphocytes 

      Vuaden, Fernanda Cenci; Savio, Luiz Eduardo Baggio; Bastos, Carolina Maria Alves [UNIFESP]; Bogo, Mauricio Reis; Bonan, Carla Denise (Elsevier B.V., 2011-01-25)
      Adenosine 5'-triphosphate (ATP) released during inflammation presents proinflammatory properties. Adenosine, produced by catabolism of ATP, is an anti-inflammatory compound. Considering the role of ATP and adenosine in ...

    • The anti-inflammatory action of the analgesic kyotorphin neuropeptide derivatives: insights of a lipid-mediated mechanism 

      Conceicao, Katia [UNIFESP]; Magalhaes, Pedro R.; Campos, Sara R. R.; Domingues, Marco M.; Ramu, Vasanthakumar G.; Michalek, Matthias; Bertani, Philippe; Baptista, Antonio M.; Heras, Montserrat; Bardaji, Eduard R.; Bechinger, Burkhard; Ferreira, Monica Lopes; Castanho, Miguel A. R. B. (Springer wien, 2016)
      Recently, a designed class of efficient analgesic drugs derived from an endogenous neuropeptide, kyotorphin (KTP, Tyr-Arg) combining C-terminal amidation (KTP-NH2) and N-terminal conjugation to ibuprofen (Ib), IbKTP-NH2, ...

    • Both adiponectin and interleukin-10 inhibit LPS-induced activation of the NF-kappa B pathway in 3T3-L1 adipocytes 

      Lira, Fábio Santos de [UNIFESP]; Rosa Neto, José Cesar [UNIFESP]; Pimentel, Gustavo Duarte [UNIFESP]; Seelaender, Marilia; Dâmaso, Ana Raimunda [UNIFESP]; Oyama, Lila Missae [UNIFESP]; Nascimento, Claudia Maria da Penha Oller do [UNIFESP] (Elsevier B.V., 2012-01-01)
      Adiponectin and interleukin 10 (IL-10) are adipokines that are predominantly secreted by differentiated adipocytes and are involved in energy homeostasis, insulin sensitivity, and the anti-inflammatory response. These two ...

    • Bradykinin inducible receptor is essential to lipopolysaccharide-induced acute lung injury in mice 

      Campanholle, Gabriela; Landgraf, Richardt G. [UNIFESP]; Borducchi, Erica; Semedo, Patricia [UNIFESP]; Wang, Pamela H. M. [UNIFESP]; Amano, Mariane T.; Russo, Momtchilo; Pacheco-Silva, Alvaro [UNIFESP]; Jancar, Sonia; Camara, Niels O. S. [UNIFESP] (Elsevier B.V., 2010-05-25)
      Lipopolysaccharides from gram-negative bacteria are amongst the most common causative agents of acute lung injury, which is characterized by an inflammatory response, with cellular infiltration and the release of ...

    • Collagen XVIII/endostatin expression in experimental endotoxemic acute renal failure 

      Cichy, Milene Cristina [UNIFESP]; Rocha, Flavia Gomes de Goes [UNIFESP]; Tristão, Vivian Regina [UNIFESP]; Pessoa, Edson de Andrade [UNIFESP]; Cenedeze, Marcos Antonio [UNIFESP]; Nürmberg Junior, R.; Schor, Nestor [UNIFESP]; Bellini, Maria Helena [UNIFESP] (Associação Brasileira de Divulgação Científica, 2009-12-01)
      Acute renal failure (ARF) is a frequent complication of Gram-negative sepsis, with a high risk of mortality. Lipopolysaccharide (LPS)-induced ARF is associated with hemodynamic changes that are strongly influenced by the ...

    • Estudos in vitro da participação da leptina em células endoteliais pulmonares de ratos nutridos e desnutridos intrauterinamente 

      Santos, Leila Aparecida dos [UNIFESP] (Universidade Federal de São Paulo, 2014-03-02)
      Studies suggest that intrauterine malnutrition can "program" the fetal tissues making them more prone to disorders associated with food, such as type 2 diabetes, metabolic syndrome and other chronic diseases in adulthood ...

    • Immune development in HIV-exposed uninfected children born to HIV-infected women 

      Miyamoto, Maristela [UNIFESP]; Gouvêa, Aida de Fátima Thomé Barbosa [UNIFESP]; Ono, Erika [UNIFESP]; Succi, Regina Célia de Menezes [UNIFESP]; Pahwa, Savita; Moraes-Pinto, Maria Isabel de [UNIFESP] (Inst Medicina Tropical Sao Paulo, 2017)
      Immunological and clinical findings suggestive of some immune dysfunction have been reported among HIV-exposed uninfected(HEU) children and adolescents. Whether these defects are persistent or transitory is still unknown. ...

    • Immune Outcomes of Paradoxical Sleep Deprivation on Cellular Distribution in Naive and Lipopolysaccharide-Stimulated Mice 

      Zager, Adriano [UNIFESP]; Ruiz, Francieli Silva [UNIFESP]; Tufik, Sergio [UNIFESP]; Andersen, Monica Levy [UNIFESP] (Karger, 2012-01-01)
      Background/Aims: Several lines of evidence indicate that sleep loss imposes significant consequences on the host defense system, including changes in cell number, activity and distribution. However, it is not clear whether ...

    • Inflammatory markers are associated with inhibitory avoidance memory deficit induced by sleep deprivation in rats 

      Esumi, Lia Assae [UNIFESP]; Palma, B. D. [UNIFESP]; Gomes, V. L. [UNIFESP]; Tufik, S. [UNIFESP]; Hipolide, D. C. [UNIFESP] (Elsevier B.V., 2011-08-01)
      Sleep deprivation (SD) causes detrimental effects to the body, such as memory impairment and weight loss. SD also changes the concentration of inflammatory mediators such as cytokines, which, in turn, can affect cognitive ...

    • Leptin Downregulates LPS-Induced Lung Injury: Role of Corticosterone and Insulin 

      Landgraf, Maristella de Almeida [UNIFESP]; Silva, Reinaldo Correia [UNIFESP]; Correa-Costa, Matheus; Hiyane, Meire Ioshie [UNIFESP]; Carvalho, Maria Helena C.; Landgraf, Richardt Gama [UNIFESP]; Câmara, Niels Olsen Saraiva [UNIFESP] (Karger, 2014-01-01)
      Background/Aims: We investigated the effects of leptin in the development of lipopolysaccharide (LPS)-induced acute lung inflammation (ALI) in lean mice. Methods: Mice were administered leptin (1.0 mu g/g) or leptin (1.0 ...