Browsing by Subject "Lipidomics"
Now showing items 1-7 of 7
-
Avaliação do papel da proteína anti-inflamatória Anexina A1 na regulação do Inflamassoma NLRP3 e nas infecções por Candida Albicans e Candida Auris: estudo in vitro e caracterização do perfil lipidômico
(Universidade Federal de São Paulo, 2020-07-17)Objetivo: Avaliar o papel da AnxA1 na regulação do inflamassoma NLRP3 e na infecção por C. albicans e C. auris em macrófagos e neutrófilos isolados, bem como avaliar o perfil dos lipídios liberados por essas células após ...
-
Effects of psychostimulants and antipsychotics on serum lipids in an animal model for schizophrenia
(MDPI AG, 2021-02-26)Schizophrenia (SCZ) treatment is essentially limited to the use of typical or atypical antipsychotic drugs, which suppress the main symptoms of this mental disorder. Metabolic syndrome is often reported in patients with ...
-
Estudo de assinaturas metabólicas em leiomiomas uterinos
(Universidade Federal de São Paulo, 2022-07-12)Objective: The present study evaluated circulating metabolites in the plasma of patients with and without leiomyomas, to define a metabolomic profile of these patients and compare them according to leiomyomas' presence and ...
-
Lipid fingerprinting in women with early-onset preeclampsia: A first look
(Elsevier B.V., 2012-07-01)Objectives: the aim of this preliminary study was to characterize the plasma lipid profiling of women with preeclampsia.Design and methods: Plasma samples of 8 pregnant women with early-onset preeclampsia and 8 normal ...
-
Metabolomics and lipidomics analyses by H-1 nuclear magnetic resonance of schizophrenia patient serum reveal potential peripheral biomarkers for diagnosis
(Elsevier Science Bv, 2017)Using H-1 NMR-based metabolomics in association to chemometrics analysis, we analyzed here the metabolic differences between schizophrenia patients (SCZ) compared to healthy controls (HCs). HCs and SCZ patients underwent ...
-
Perfil de hormônios e lipídios circulantes em pacientes com lipodistrofia generalizada congênita em resposta à ingestão alimentar
(Universidade Federal de São Paulo (UNIFESP), 2020-07-31)Patients with congenital generalized lipodystrophy (CGL) are not able to store lipids in the adipose tissue, which causes hypoleptinemia, increased appetite, ectopic fat deposition and lipotoxicity. However, a direct ...
-
Recent advances in lipidomics: Analytical and clinical perspectives
(Elsevier Science Inc, 2017)Lipidomics or lipid-profiling is a lipid-targeted metabolomics approach aiming at comprehensive analysis of lipids in biological systems. The extent of information in the genomic and proteomic fields is greater than that ...
