Now showing items 1-10 of 19

    • Cafestol, a diterpene molecule found in coffee, induces leukemia cell death 

      Limaa, Caue S. [UNIFESP]; Spindola, Daniel G. [UNIFESP]; Bechara, Alexandre [UNIFESP]; Garcia, Daniel M. [UNIFESP]; Palmeira-dos-Santos, Caroline [UNIFESP]; Peixoto-da-Silva, Janaina [UNIFESP]; Erustes, Adolfo G. [UNIFESP]; Michelin, Luis F. G. [UNIFESP]; Pereira, Gustavo J. S. [UNIFESP]; Smaili, Soraya S. [UNIFESP]; Paredes-Gamero, Edgar [UNIFESP]; Calgarotto, Andrana K. [UNIFESP]; Oliveira, Carlos R. [UNIFESP]; Bincoletto, Claudia [UNIFESP] (Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)
      To evaluate the antitumor properties of Cafestol four leukemia cell lines were used (NB4, K562, HL60 and KG1). Cafestol exhibited the highest cytotoxicity against HL60 and KG1 cells, as evidenced by the accumulation of ...

    • Canthin-6-one induces cell death, cell cycle arrest and differentiation in human myeloid leukemia cells 

      Vieira Torquato, Heron F. [UNIFESP]; Ribeiro-Filho, Antonio C.; Buri, Marcus V. [UNIFESP]; Araujo Junior, Roberto T. [UNIFESP]; Pimenta, Renata [UNIFESP]; de Oliveira, Jose Salvador R. [UNIFESP]; Filho, Valdir C.; Macho, Antonio; Paredes-Gamero, Edgar J. [UNIFESP]; de Oliveira Martins, Domingos T. (Elsevier Science Bv, 2017)
      Background: Canthin-6-one is a natural product isolated from various plant genera and from fungi with potential antitumor activity. In the present study, we evaluate the antitumor effects of canthin-6-one in human myeloid ...

    • Cefepime monotherapy is as effective as ceftriaxone plus amikacin in pediatric patients with cancer and high-risk febrile neutropenia in a randomized comparison 

      Pires Pereira, Carlos Alberto [UNIFESP]; Petrilli, Antonio Sergio [UNIFESP]; Carlesse, Fabianne Altruda; Vercillo Luisi, Flavio Augusto; Torres Barros da Silva, Katia Veronica; Martino Lee, Maria Lucia de (Scientific Communications Int Ltd, 2009-04-01)
      Background and purpose: The empirical use of antibiotic therapy is widely accepted for patients with fever and neutropenia during cancer chemotherapy. The use of intravenous monotherapy with broad-spectrum antibiotics in ...

    • Classificação dos tumores hematopoéticos e linfoides de acordo com a OMS: padronização da nomenclatura em língua portuguesa, 4ª edição 

      Zerbini, Maria Cláudia Nogueira; Soares, Fernando Augusto; Morais, José Carlos; Vassallo, José; Velloso, Elvira Deolinda Rodrigues Pereira; Chauffaille, Maria de Lourdes Lopes Ferrari [UNIFESP]; Chiattone, Carlos Sergio; Aldred, Vera Lucia; Siqueira, Sheila Aparecida Coelho; Alves, Antonio Correa [UNIFESP]; Castelli, Jussara Bianchi; Oliveira, Claudia Regina Gomes Mendes Cardim de; Menezes, Yara de; Paes, Roberto Pinto (Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia, 2011-12-01)
      INTRODUCTION: The World Health Organization (WHO) classification of hematopoietic and lymphoid tissue (4th edition, 2008) tumors constitutes an updated review of the 3rd edition published in 2001. The translation of the ...

    • Combined method for simultaneous morphology, immunophenotype and karyotype (MAC) in leukemias 

      Chauffaille, Maria de Lourdes Lopes Ferrari [UNIFESP]; Coutinho, Vicente [UNIFESP]; Yamamoto, Mihoko [UNIFESP]; Kerbauy, José [UNIFESP] (Associação Paulista de Medicina - APM, 1997-02-01)
      In the present study, a combined method (CM) for attaining simultaneous identification of leukemic cell morphology, karyotype and immunophenotype has been evaluated in 21 patients with acute leukemia and 1 with CML in blast ...

    • Dental maturity assessment in children with acute lymphoblastic leukemia after cancer therapy 

      Vasconcelos, Niucha P. S. [UNIFESP]; Caran, Eliana M. M. [UNIFESP]; Lee, Maria Lucia [UNIFESP]; Lopes, Nilza N. F. [UNIFESP]; Weiler, Rosa M. E. [UNIFESP] (Elsevier B.V., 2009-01-30)
      Dental age is largely used in both forensic studies and clinical practice. All over the world, many Studies have been made to determine chronological age using dental ages of individuals, but selecting individuals with no ...

    • Efeitos tardios dos praguicidas organoclorados no homem 

      Nunes, Mônica Vannucci [UNIFESP]; Tajara, Eloiza Helena (Faculdade de Saúde Pública da Universidade de São Paulo, 1998-08-01)
      Available information on organochlorines and the chronic effects of exposure to them are set out. Organochlorinated compounds are the most persistent pesticides and can be found in all ecosystems. Although they are generally ...

    • Estratégias analíticas integradas para obtenção de metabólitos citotóxicos a partir de Swinglea glutinosa e Penicillium setosum, um endofítico associado 

      Carvalho, Ana Calheiros de [UNIFESP] (Universidade Federal de São Paulo, 2021-10-08)
      Neste trabalho, foi conduzido o estudo químico da espécie vegetal Swinglea glutinosa (Rutaceae) e do metabolismo secundário de seus fungos endofíticos associados. Para isto, foi proposta a utilização da abordagem de ...

    • Estudo do perfil químico da espécie vegetal Vicia faba (Fabaceae): busca racional por subtâncias anti-leucemia 

      Sipoloni, Victor Menezes [UNIFESP] (Universidade Federal de São Paulo, 2021)
      O estudo de Produtos Naturais (PNs) cresceu significantemente no decorrer dos anos na busca por novas substâncias com diversas finalidades. Pesquisas mostraram o potencial de PNs para o uso clínico de diversas doenças, ...

    • Expressão dos receptores de fibronectina nas leucemias agudas da infância 

      Yamamoto, Mihoko [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 1991)