Now showing items 1-1 of 1

    • The anti-inflammatory action of the analgesic kyotorphin neuropeptide derivatives: insights of a lipid-mediated mechanism 

      Conceicao, Katia [UNIFESP]; Magalhaes, Pedro R.; Campos, Sara R. R.; Domingues, Marco M.; Ramu, Vasanthakumar G.; Michalek, Matthias; Bertani, Philippe; Baptista, Antonio M.; Heras, Montserrat; Bardaji, Eduard R.; Bechinger, Burkhard; Ferreira, Monica Lopes; Castanho, Miguel A. R. B. (Springer wien, 2016)
      Recently, a designed class of efficient analgesic drugs derived from an endogenous neuropeptide, kyotorphin (KTP, Tyr-Arg) combining C-terminal amidation (KTP-NH2) and N-terminal conjugation to ibuprofen (Ib), IbKTP-NH2, ...