Now showing items 1-2 of 2

    • Characterization of thrombin inhibitory mechanism of rAaTI, a Kazal-type inhibitor from Aedes aegypti with anticoagulant activity 

      Watanabe, Renata Midori Okuta [UNIFESP]; Tanaka-Azevedo, Anita M.; Araujo, Mariana da Silva [UNIFESP]; Juliano, Maria Aparecida [UNIFESP]; Tanaka, Aparecida Sadae [UNIFESP] (Elsevier B.V., 2011-03-01)
      Saliva of blood-sucking arthropods contains a complex mixture of anti-haemostatic, anti-inflammatory and immune-modulator compounds. Among anti-haemostatic factors, there are anticoagulants, vasodilators and platelet ...

    • A novel trypsin Kazal-type inhibitor from Aedes aegypti with thrombin coagulant inhibitory activity 

      Watanabe, Renata M. O. [UNIFESP]; Soares, Tatiane S. [UNIFESP]; Morais-Zani, Karen; Tanaka-Azevedo, Anita M.; Maciel, Ceres; Capurro, Margareth L.; Torquato, Ricardo J. S. [UNIFESP]; Tanaka, Aparecida S. [UNIFESP] (Elsevier B.V., 2010-08-01)
      Kazal-type inhibitors play several important roles in invertebrates, such as anticoagulant, vasodilator and antimicrobial activities. Putative Kazal-type inhibitors were described in several insect transcriptomes. in this ...