Browsing by Subject "Kallikrein-kinin system"
Now showing items 1-6 of 6
-
Cardioprotective effect of ornitho-kinin in an anesthetized, open-chest chicken model of acute coronary occlusion
(Associação Brasileira de Divulgação Científica, 2009-09-01)The generation of bradykinin (BK; Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg) in blood and kallidin (Lys-BK) in tissues by the action of the kallikrein-kinin system has received little attention in non-mammalian vertebrates. In ...
-
Characteristics of neural and humoral systems involved in the regulation of blood pressure in snakes
(Elsevier B.V., 2007-07-01)Cardiovascular function is affected by many mechanisms, including the autonomic system, the kallikrein-kinin system (KKS), the reninangiotensin system (RAS) and the endothelin system. the function of these systems seems ...
-
Deficient prolylcarboxypeptidase gene and protein expression in left ventricles of spontaneously hypertensive rats (SHR)
(Elsevier B.V., 2014-11-01)Prolylcarboxypeptidase (PRCP), an endothelial cell membrane serine peptidase that inactivates angiotensin II and activates pre-kallikrein, is thought to have anti-hypertensive and anti-proliferative roles in cardiovascular ...
-
Efeitos da obesidade no sistema calicreína-cininas: estudo dos receptores B1 e B2 de cininas em tecido adiposo humano e murino
(Universidade Federal de São Paulo (UNIFESP), 2006-06-28)Objectives: To study the effect of obesity on the kallikrein-kinin system through the expression of receptors B1 and B2 on humans and mice, and alterations in the synthesis and functionality of the receptor in murine ...
-
Interação do sistema calicreínas-cininas e fator de crescimento vascular endotelial (VEGF) em modelos de hipóxia intermitente: avaliação da angiogênese cardíaca nos animais selvagens e nocautes do receptor B2 de bradicinina
(Universidade Federal de São Paulo (UNIFESP), 2016-02-29)Low levels of oxygen in the tissues (hypoxia) occur in a number of pathophysiologic conditions such as the growth of tumors, heart disease and obstructive sleep apnea. During hypoxia, blood vessel growth (angiogenesis) is ...
-
Receptor B1 de cininas modula marcadores moleculares da adipogênese
(Universidade Federal de São Paulo, 2023-07-20)Introdução: O sistema calicreína-cininas tem seus efeitos mediados por dois receptores acoplados à proteína G chamados de B1 e B2. O receptor B1 (B1R) está associado a situações patológicas, contudo, novos achados atribuem ...
