Browsing by Subject "Innate immunity"

Now showing items 1-10 of 10

    • Análise da função de receptores da imunidade inata no desenvolvimento da esclerose lateral amiotrófica experimental 

      Silva, Denise Correia [UNIFESP] (Universidade Federal de São Paulo, 2021-10-25)
      A neuroinflamação é um processo que desempenha papel importante na progressão de doenças neurodegenerativas como a Esclerose Lateral Amiotrófica (ELA), que é caracterizada pela morte de neurônios motores e progressiva ...

    • Differential expression of toll-like receptor signaling cascades in LPS-tolerant human peripheral blood mononuclear cells 

      Mendes, Marialice Erdelyi [UNIFESP]; Baggio-Zappia, Giovana Lotici [UNIFESP]; Colo Brunialti, Milena Karina [UNIFESP]; Fernandes, Maria da Luz [UNIFESP]; Rapozo, Marjorie Marini [UNIFESP]; Salomao, Reinaldo [UNIFESP] (Elsevier B.V., 2011-03-01)
      Pre-exposure to low doses of LPS induces resistance to a lethal challenge, a phenomenon known as endotoxin tolerance. in this study, tolerance was induced in human PBMC by culturing cells with 1 ng/mL LPS for 48 h. Cells ...

    • Doença de Chagas: aspectos gerais e imunopatogenia com foco para a atuação das células B-1 durante a infecção - uma revisão bibliográfica 

      Queiroz, Júlia Fonseca [UNIFESP] (Universidade Federal de São Paulo, 2022-12-07)
      A doença de Chagas é uma zoonose negligenciada causada pelo protozoário Trypanosoma cruzi, que apresenta grande importância epidemiológica e que nos últimos anos tem se disseminado para fora da área endêmica. Ainda há ...

    • Glycolipid Sensing and Innate Immunity in Paracoccidioidomycosis 

      Batista, Vanessa G.; Toledo, Marcos S. [UNIFESP]; Straus, Anita H. [UNIFESP]; Mendes-Giannini, Maria J. S.; Duarte, Alberto J. S.; Takahashi, Helio K. [UNIFESP]; Benard, Gil (Springer, 2014-10-01)
      Distinct glycolipid profiles are described in microorganisms, which have been shown to modulate the innate immune system. We tested the hypothesis that glycosphingolipids from Paracoccidioides brasiliensis have immunomodulatory ...

    • Leishmania enriettii: biochemical characterisation of lipophosphoglycans (LPGs) and glycoinositolphospholipids (GIPLs) and infectivity to Cavia porcellus 

      Paranaiba, Larissa Ferreira; Assis, Rafael Ramiro de; Nogueira, Paula Monalisa; Torrecilhas, Ana Claudia [UNIFESP]; Campos, Joao Henrique [UNIFESP]; Silveira, Amanda Cardoso de Oliveira; Martins-Filho, Olindo Assis; Pessoa, Natalia Lima; Campos, Marco Antonio; Parreiras, Patricia Martins; Melo, Maria Norma; Gontijo, Nelder de Figueiredo; Soares, Rodrigo Pedro Pinto (Biomed Central Ltd, 2015-01-17)
      Background: Leishmania enriettii is a species non-infectious to man, whose reservoir is the guinea pig Cavia porcellus. Many aspects of the parasite-host interaction in this model are unknown, especially those involving ...

    • Novel androgen-induced activity of an antimicrobial beta-defensin: Regulation of Wolffian duct morphogenesis 

      Ribeiro, Camilla M. [UNIFESP]; Ferreira, Lucas G. A. [UNIFESP]; Thimoteo, Daniel S. [UNIFESP]; Smith, Lee B.; Hinton, Barry T.; Avellar, Maria Christina W. [UNIFESP] (Elsevier Ireland Ltd, 2017)
      The Wolffian duct (WD) undergoes morphological changes induced by androgens to form the epididymis, which is an organ essential for sperm maturation. Androgen action in WD epithelium involves paracrine factors of mesenchymal ...

    • Propionibacterium acnes induces an adjuvant effect in B-1 cells and affects their phagocyte differentiation via a TLR2-mediated mechanism 

      Gambero, Monica [UNIFESP]; Teixeira, Daniela [UNIFESP]; Butin, Liane [UNIFESP]; Ishimura, Mayari Eika [UNIFESP]; Mariano, Mario [UNIFESP]; Popi, Ana Flavia [UNIFESP]; Longo-Maugeri, Ieda Maria [UNIFESP] (Elsevier Gmbh, Urban & Fischer Verlag, 2016)
      B-1 lymphocytes are present in large numbers in the mouse peritoneal cavity, as are macrophages, and are responsible for natural IgM production. These lymphocytes migrate to inflammatory foci and are also involved in innate ...

    • Rmcystatin3, a cysteine protease inhibitor from Rhipicephalus microplus hemocytes involved in immune response 

      Lu, Stephen [UNIFESP]; Soares, Tatiane Sanches [UNIFESP]; Vaz Junior, Itabajara S.; Lovato, Diogo Ventura [UNIFESP]; Tanaka, Aparecida Sadae [UNIFESP] (Elsevier B.V., 2014-11-01)
      The Rhipicephalus microplus tick is responsible for losses in the livestock production estimated in 2 billions USD. Despite its economical importance the knowledge in tick's physiology is sparse. in order to contribute to ...

    • TLR-2 and TLR-4 expression in monocytes of newborns with late-onset sepsis 

      Redondo, Ana Carolina Costa; Ceccon, Maria Esther Jurfest Rivero; Silveira-Lessa, Ana Lúcia; Quinello, Camila; Palmeira, Patricia; Carvalho, Werther Brunow [UNIFESP]; Carneiro-Sampaio, Magda Maria Sales (Soc Brasil Pediatria, 2014-09-01)
      Objective: To analyze toll-like receptor (TLR)-2 and TLR-4 expression in monocytes of newborns with late-onset sepsis.Methods: This prospective study included 27 full-term newborns aged 8 to 29 days, with clinical and ...

    • TLR4 mRNA Levels as Tools to Estimate Risk for Early Posttransplantation Kidney Graft Dysfunction 

      Andrade-Oliveira, Vinicius [UNIFESP]; Campos, Erika F. [UNIFESP]; Goncalves-Primo, Amador; Grenzi, Patricia C. [UNIFESP]; Medina-Pestana, Jose O. [UNIFESP]; Tedesco-Silva, Helio; Gerbase-DeLima, Maria [UNIFESP] (Lippincott Williams & Wilkins, 2012-09-27)
      Background. the participation of Toll-like receptor (TLR) 4, an innate immunity receptor, has been previously demonstrated in the pathogenesis of acute renal injury. We aimed to investigate whether messenger RNA (mRNA) ...