Now showing items 1-10 of 10

    • Autoimmune uveitis: the associated proinflammatory molecules and the search for immunoregulation 

      Commodaro, Alessandra Goncalves [UNIFESP]; Bueno, Valquiria [UNIFESP]; Belfort, Rubens [UNIFESP]; Rizzo, Luiz Vicente (Elsevier B.V., 2011-02-01)
      Uveitis is an intraocular inflammatory disease causing a significant visual impairment. the disease can be idiopathic, associated with infectious and systemic disorders or arisen from an unknown cause. Over the last 20 ...

    • The dual effect of paradoxical sleep deprivation on murine immune functions 

      Sa-Nunes, Anderson; Bizzarro, Bruna; Egydio, Flavia [UNIFESP]; Barros, Michele S.; Sesti-Costa, Renata; Soares, Elyara M.; Pina, Adriana; Russo, Momtchilo; Faccioli, Lucia H.; Tufik, Sergio [UNIFESP]; Andersen, Monica L. [UNIFESP] (Elsevier Science Bv, 2016)
      We aimed to evaluate the effect of paradoxical sleep deprivation on the cellular migration during inflammation, the peritoneal macrophage phenotype and the infectious stimulus outcomes. A/J mice were inoculated with ...

    • The dual effect of paradoxical sleep deprivation on murine immune functions 

      Sa-Nunes, Anderson; Bizzarro, Bruna; Egydio, Flavia [UNIFESP]; Barros, Michele S.; Sesti-Costa, Renata; Soares, Elyara M.; Pina, Adriana; Russo, Momtchilo; Faccioli, Lucia H.; Tufik, Sergio [UNIFESP]; Andersen, Monica L. [UNIFESP] (Elsevier Science Bv, 2016)
      We aimed to evaluate the effect of paradoxical sleep deprivation on the cellular migration during inflammation, the peritoneal macrophage phenotype and the infectious stimulus outcomes. A/J mice were inoculated with ...

    • The first pacifastin elastase inhibitor characterized from a blood sucking animal 

      Marco, Renato de [UNIFESP]; Lovato, Diogo V. [UNIFESP]; Torquato, Ricardo J. S. [UNIFESP]; Clara, Renan O. [UNIFESP]; Buarque, Diego S. [UNIFESP]; Tanaka, Aparecida S. [UNIFESP] (Elsevier B.V., 2010-07-01)
      Pacifastin-like protease inhibitors belong to a recent classified protease inhibitor family and they are the smallest protease inhibitors described in animals. in this work, we purified and characterized, for the first ...

    • Hormone replacement therapy increases levels of antibodies against heat shock protein 65 and certain species of oxidized low density lipoprotein 

      Uint, Luciana; Gebara, Otávio Celso Eluf; Pinto, Lígia B.; Wajngarten, Maurício; Boschcov, Paulo [UNIFESP]; Luz, Protásio Lemos da; Gidlund, Magnus (Associação Brasileira de Divulgação Científica, 2003-04-01)
      Hormone replacement therapy (HRT) reduces cardiovascular risks, although the initiation of therapy may be associated with transient adverse ischemic and thrombotic events. Antibodies against heat shock protein (Hsp) and ...

    • Infection by the Sylvio X10/4 clone of Trypanosoma cruzi: relevance of a low-virulence model of Chagas' disease 

      Marinho, Claudio R. F. [UNIFESP]; Nunez-Apaza, Luis N.; Bortoluci, Karina R. [UNIFESP]; Bombeiro, Andre L.; Bucci, Daniella Z.; Grisotto, Marcos G.; Sardinha, Luiz R.; Jorquera, Christian E.; Lira, Sergio; D'Imperio Lima, Maria Regina; Alvarez, Jose M. (Elsevier B.V., 2009-11-01)
      The physiopathology of Chagas' disease has been largely defined in murine infections with virulent strains which partially represent parasite diversity This report reviews our studies with Sylvio X10/4 parasites. a Trypanosoma ...

    • Moderate exercise increases the metabolism and immune function of lymphocytes in rats 

      Navarro, Francisco; Nova Bacurau, Aline Villa; Pereira, Guilherme Borges; Araujo, Ronaldo Carvalho [UNIFESP]; Almeida, Sandro Soares [UNIFESP]; Moraes, Milton Rocha [UNIFESP]; Uchida, Marco Carlos; Pereira Costa Rosa, Luis Fernando Bicudo; Navalta, James; Prestes, Jonato; Pereira Bacurau, Reury Frank (Springer, 2013-05-01)
      Exercise modulates both glucose and glutamine metabolism which influences lymphocyte function. We investigated the influence of chronic moderate exercise on glucose and glutamine metabolism in lymphocytes, the associated ...

    • Partial protective responses induced by a recombinant cysteine proteinase from Leishmania (Leishmania) amazonensis in a murine model of cutaneous leishmaniasis 

      Cardoso Fedeli, Carlos Eduardo; Ferreira, Josie Haydée Lima [UNIFESP]; Mussalem, Juliana Sekeres; Longo-Maugeri, Ieda Maria; Gentil, Luciana Girotto; Machado dos Santos, Marcia Regina; Katz, Simone; Barbieri, Clara Lucia [UNIFESP] (Elsevier B.V., 2010-02-01)
      A 500 bp fragment encoding an isoform of cysteine proteinase from Leishmania (Leishmania) amazonensis was subcloned and expressed in the pHis vector, resulting in a recombinant protein of 24 kDa, rLacys24. in Western blots ...

    • Participação das vesículas extracelulares de leveduras de Sporothrix brasiliensis na resposta imune da Esporotricose: estudo ex vivo e in vivo 

      Ikeda, Marcelo Augusto Kazuo [UNIFESP] (Universidade Federal de São Paulo, 2018-02-19)
      Sporotrichosis is a mycotic emerging infectious disease, it affects the skin, lymphatic system, and other organs from humans and animals. The fungus infection has a worldwide distribution and is endemic in areas from ...

    • Resposta imunológica e leishmania amazonensis: uma revisão de literatura 

      Kopel, Giovana Macedo [UNIFESP] (Universidade Federal de São Paulo, 2022-02-07)
      Leishmaniose é uma doença infecciosa causada por protozoários do gênero Leishmania. A espécie Leishmania amazonensis, um dos agentes etiológicos da leishmaniose cutânea, apresenta características únicas pois demonstra ...