Now showing items 1-10 of 13

    • Blockage of Wnt/beta-catenin signaling by quercetin reduces survival and proliferation of B-1 cells in vitro 

      Tavares Novo, Marilia Campos [UNIFESP]; Osugui, Lika [UNIFESP]; Reis, Vanessa Oliveira dos [UNIFESP]; Longo-Maugeri, Ieda Maria [UNIFESP]; Mariano, Mario [UNIFESP]; Popi, Ana Flavia [UNIFESP] (Elsevier B.V., 2015-01-01)
      The Wnt/beta-catenin signaling pathway has been shown to play an important role in controlling the proliferation, survival and differentiation of hematopoietic cells. Several Wnt/beta-catenin signaling components influence ...

    • Critical involvement of Th1-related cytokines in renal injuries induced by ischemia and reperfusion 

      Paiva, Vanessa Nunes de [UNIFESP]; Monteiro, Rebecca M. M. [UNIFESP]; Marques, Vilmar de Paiva; Cenedeze, Marcos Antonio [UNIFESP]; Teixeira, Vicente de P. A.; Reis, Marlene A. dos; Pacheco-Silva, Alvaro [UNIFESP]; Camara, Niels O. S. [UNIFESP] (Elsevier B.V., 2009-06-01)
      Renal ischemia and reperfusion injury (IRI) is considered an inflammatory syndrome. To move forward in its pathogenesis, we exploited the role of several cytokines on renal damages triggered by IRI. Specifically to evaluate ...

    • Efeito fotoprotetor e imunomodulador dos extratos de Bellis perennis e Polypodium leucotomos em queratinócitos: estudos in vitro 

      Ribeiro, Vivian (Universidade Federal de São Paulo, 2021-06-30)
      Objetivos: Avaliar o potencial uso do extrato da planta de Bellis perennis (BPE) em cosmecêuticos como fator fotoprotetor, usando um modelo in vitrode dano de queratinócito induzido por UVA. Métodos: Queratinócitos humanos ...

    • Efeitos da suplementação com melatonina sobre a expressão de adipocinas por tecidos adiposos branco em camundongos obesos 

      Paixão, Regislane Ino da [UNIFESP] (Universidade Federal de São Paulo, 2017-07-03)
      Several metabolic disorders such as obesity, type 2 diabetes mellitus (DM2) and metabolic syndrome have a direct association with white adipose tissue (WAT) dysfunction and, consequently, adipokines secretion, especially ...

    • Effect of natural porcine surfactant in Staphylococcus aureus induced pro-inflammatory cytokines and reactive oxygen species generation in monocytes and neutrophils from human blood 

      Guevara, Yuliannis Lugones Ladron de; Hidalgo, Odalys Blanco; Santos, Sidneia Sousa [UNIFESP]; Brunialti, Milena Karina Coló [UNIFESP]; Faure, Roberto; Salomão, Reinaldo [UNIFESP] (Elsevier B.V., 2014-08-01)
      Surfacen (R) is a clinical surfactant preparation of porcine origin. in the present study, we have evaluated the effect of Surfacen (R) in the modulation of oxidative burst in monocytes and neutrophils in human blood and ...

    • Epstein-Barr viral load, interleukin-6 and interleukin-10 levels in post-transplant lymphoproliferative disease: A nested case-control study in a renal transplant cohort 

      Baiocchi, Otavio Carvalho Guimarães [UNIFESP]; Colleoni, Gisele Wally Braga [UNIFESP]; Caballero, Otávia L.; Vettore, André L.; Bulgarelli, Adriana; Dalboni, Maria Aparecida [UNIFESP]; Granato, Celso Francisco Hernandes [UNIFESP]; Franco, Marcello Fabiano de [UNIFESP]; Pestana, Jose Osmar Medina [UNIFESP] (Taylor & Francis Ltd, 2005-04-01)
      The possible correlation among Epstein - Barr virus (EBV) load, interleukin-6 (IL-6) and interleukin-10 (IL-10) levels has become an attractive issue and can provide a useful tool for diagnosis and monitoring of patients ...

    • Expressão de CD40 e CD40-L e produção de citocinas em pacientes com ataxiatelangiectasia 

      Pereira, Camila Teles Machado [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2015-08-07)
      A deficiência imunológica que acompanha os pacientes com ataxia telangiectasia (AT) é bastante variável e geralmente combinada. As alterações humorais mais comuns incluem redução no número de linfócitos B, nos níveis de ...

    • Gastric Bypass and Sleeve Gastrectomy: the Same Impact on IL-6 and TNF-alpha. Prospective Clinical Trial 

      Viana, Elaine Cristina; Araujo-Dasilio, Karine L.; Soares Miguel, Gustavo Peixoto; Bressan, Josefina; Lemos, Elenice Moreira; Moyses, Margareth Ribeiro; Abreu, Glaucia Rodrigues de; Moreira Coutinho de Azevedo, Joao Luiz [UNIFESP]; Carvalho, Perseu Seixas; Passos-Bueno, Maria Rita S.; Valle Errera, Flavia Imbroisi; Bissoli, Nazare Souza (Springer, 2013-08-01)
      Due to the association between the quantity of adipose tissue and concentrations of interleukin-6 (IL-6) and tumor necrosis factor (TNF-alpha), this work aimed to assess the effects of Roux-en-Y gastric bypass (RYGB) and ...

    • Human monocytes tolerant to LPS retain the ability to phagocytose bacteria and generate reactive oxygen species 

      Fernandes, Maria da Luz [UNIFESP]; Mendes, Marialice Erdelyi [UNIFESP]; Brunialti, Milena Karina Coló [UNIFESP]; Salomão, Reinaldo [UNIFESP] (Associação Brasileira de Divulgação Científica, 2010-09-01)
      Tolerance to lipopolysaccharide (LPS) occurs when animals or cells exposed to LPS become hyporesponsive to a subsequent challenge with LPS. This mechanism is believed to be involved in the down-regulation of cellular ...

    • Interleukin-6 polymorphisms and the risk of cervical cancer 

      Souza, NCN de; Brenna, SMF; Campos, F.; Syrjanen, K. J.; Baracat, Edmund Chada [UNIFESP]; Silva, Ismael Dale Cotrim Guerreiro da [UNIFESP] (Blackwell Publishing, 2006-05-01)
      Recent data implicate that cytokine gene polymorphisms are important in pathogenesis of various neoplastic and nonneoplastic human diseases, and it was recently suggested that polymorphisms in interleukin (IL)-6 might ...