Browsing by Subject "IL-4"

Now showing items 1-5 of 5

    • Effect of doxorubicin on cytokine production by lymphocytes and the Th1/Th2 balance 

      Santos, Ronaldo Vagner Thomatieli dos [UNIFESP]; Caperuto, E. C.; Mello, Marco Tulio de [UNIFESP]; Costa Rosa, L. F. B. P. (Elsevier B.V., 2010-10-01)
      Doxorubicin (DOXO) is a potent chemotherapeutic used mainly against solid tumours; however, it has several side effects that can limit its clinical use. On the other hand, the effect of DOXO upon lymphocyte function is ...

    • Immune cellular parameters of leprosy and human immunodeficiency virus-1 co-infected subjects 

      Carvalho, Karina I. [UNIFESP]; Maeda, Solange [UNIFESP]; Marti, Luciana; Yamashita, Jane [UNIFESP]; Haslett, Patrick A. J.; Kallas, Esper Georges [UNIFESP] (Wiley-Blackwell, 2008-06-01)
      Leprosy and human immunodeficiency virus-1 (HIV-1) are examples of human infections where interactions between the pathogen and the host cellular immunity determine the clinical manifestations of disease. Hence, a significant ...

    • Interleukin-4 and soluble CD23 serum levels in asthmatic atopic children 

      Daher, S.; Santos, LMB; Sole, D.; Delima, M. G.; Naspitz, C. K.; Musatti, C. C. (J R Prous Sa, 1995-09-01)
      IL-4 is an essential mediator of IgE synthesis; it also upregulates the expression of the low affinity receptor for IgE (CD23) and its release in soluble form (sCD23). The involvement of IL-4 and sCD23 on the IgE synthesis ...

    • More stories on Th17 cells 

      Basso, Alexandre Salgado [UNIFESP]; Cheroutre, Hilde; Mucida, Daniel (Nature Publishing Group, 2009-04-01)
      For more than two decades, immunologists have been using the so-called Th1/Th2 paradigm to explain most of the phenomena related to adaptive immunity. the Th1/Th2 paradigm implied the existence of two different, mutually ...

    • Murine macrophages cultured with IL-4 acquire a phenotype similar to that of epithelioid cells from granulomatous inflammation 

      Cipriano, Ivone Martins [UNIFESP]; Mariano, Mario [UNIFESP]; Freymuller, Edna [UNIFESP]; Carneiro, Celia Regina Whitaker [UNIFESP] (Kluwer Academic/plenum Publ, 2003-08-01)
      Epithelioid cells (ECs) found in granulomas are thought to derive from mononuclear phagocytes. Although GM-CSF and/or IL-4 are known to promote cell differentiation their role in the development of ECs has never been ...