Browsing by Subject "IL-12"

Now showing items 1-4 of 4

    • Critical involvement of Th1-related cytokines in renal injuries induced by ischemia and reperfusion 

      Paiva, Vanessa Nunes de [UNIFESP]; Monteiro, Rebecca M. M. [UNIFESP]; Marques, Vilmar de Paiva; Cenedeze, Marcos Antonio [UNIFESP]; Teixeira, Vicente de P. A.; Reis, Marlene A. dos; Pacheco-Silva, Alvaro [UNIFESP]; Camara, Niels O. S. [UNIFESP] (Elsevier B.V., 2009-06-01)
      Renal ischemia and reperfusion injury (IRI) is considered an inflammatory syndrome. To move forward in its pathogenesis, we exploited the role of several cytokines on renal damages triggered by IRI. Specifically to evaluate ...

    • Differential inhibitory mechanism of cyclic AMP on TNF-alpha and IL-12 synthesis by macrophages exposed to microbial stimuli 

      Procópio, Daniela O. [UNIFESP]; Teixeira, Mauro M.; Camargo, Maristela M.; Travassos, Luiz R.; Ferguson, Michael AJ; Almeida, Igor C.; Gazzinelli, Ricardo T. (Stockton Press, 1999-07-01)
      1 Microbial stimuli such as bacterial lipopolysaccharide (LPS) or glycosylphosphatidylinositol-mucins derived from Trypanosoma cruzi trypomastigotes (tGPI-mucins) are effective stimulators of the synthesis of cytokines by ...

    • Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae 

      Pelizon, Ana Claudia; Kaneno, Ramon; Soares, Angela Maria Victoriano de Campos [UNIFESP]; Meira, Domingos Alves [UNIFESP]; Sartori, Alexandrina (Acad Sciences Czech Republic, Inst Physiology, 2005-01-01)
      In this study we investigated the effect of beta-glucan derived from Saccharomyces cerevisiae on fungicidal activity, cytokine production and natural killer activity. Spleen and peritoneal cells from female C57BL/6 mice, ...

    • Interleukin-12 protects mice against disseminated infection caused by Paracoccidioides brasiliensis but enhances pulmonary inflammation 

      Arruda, C.; Franco, M. F.; Kashino, S. S.; Nascimento, FRF; Fazioli, R. D.; Vaz, CAC; Russo, M.; Calich, VLG (Elsevier B.V., 2002-05-01)
      Paracoccidioides brasiliensis is a facultative, intracellular pathogen causing the most important deep mycosis in Latin America. As the production of IFN-gamma and induction of cell-mediated immunity to P. brasiliensis is ...