Now showing items 1-10 of 13

    • Absence of mutations in Pax6 gene in three cases of Morning Glory syndrome associated with isolated growth hormone deficiency 

      Guerra-Junior, Gil; Spinola-Castro, Angela Maria [UNIFESP]; Siviero-Miachon, Adriana A. [UNIFESP]; Nogueira, Roberto Gomes [UNIFESP]; Lemos-Marini, Sofia Helena Valente de; D'Souza-li, Lilia Freire Rodrigues; Silva, Priscila Cristina da; França, Emerson Salvador S.; Soardi, Fernanda Caroline; Mello, Maricilda Palandi de [UNIFESP] (Sociedade Brasileira de Endocrinologia e Metabologia, 2008-11-01)
      Morning glory syndrome (MGS) is a congenital optic disc dysplasia often associated with craniofacial anomalies, especially basal encephalocele and hypopituitarism. Clinical signs are varied and often occult. The PAX6 gene ...

    • Baixa estatura na doença renal crônica: fisiopatologia e tratamento com hormônio de crescimento 

      Oliveira, Josenilson Campos De; Siviero-Miachon, Adriana A. [UNIFESP]; Spinola-Castro, Angela Maria [UNIFESP]; Belangero, Vera Maria Santoro; Guerra-Junior, Gil (Sociedade Brasileira de Endocrinologia e Metabologia, 2008-07-01)
      Growth failure is frequent and a clinically important issue in children with chronic kidney disease (CKD). Many factors contribute to impaired growth in these children, including abnormalities in the growth hormone (GH) - ...

    • Controle neuroendócrino da massa óssea: mito ou verdade? 

      Borba, Victoria Zeghbi Cochenski [UNIFESP]; Kulak, Carolina Aguiar Moreira; Lazaretti-Castro, Marise [UNIFESP] (Sociedade Brasileira de Endocrinologia e Metabologia, 2003-08-01)
      Bone remodeling is a physiologic process regulated by the interaction between the bone cells and a variety of hormones, cytokines, growth factors and inflammatory mediators. The central nervous system (CNS) has been proposed ...

    • Efeitos da ghrelina, GHRP-6 e GHRH sobre a secreção de GH, ACTH e cortisol em pacientes com diabetes mellitus tipo 1 

      Sa, Larissa Bianca Paiva Cunha de [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2009-06-24)
      In type 1 diabetes mellitus (T1DM), GH responses to provocative stimuli are normal or exaggerated while the hypothalamic-pituitary-adrenal axis has been less studied. Ghrelin is a GH-secretagogue which also increases ACTH ...

    • First Two Years' Response to Growth Hormone Treatment in Very Young Preterm Small for Gestational Age Children 

      Garcia, R. A. M.; Longui, C. A.; Kochi, C.; Arruda, M.; Faria, C. D. C.; Calliari, L. E. P.; Monte, O.; Pachi, P. R.; Saenger, P. (Karger, 2009-01-01)
      Background: Growth hormone (GH) is a therapeutic option for small for gestational age (SGA) children without spontaneous catch-up. There are few reports on preterm SGA children. Prematurity is an additional risk factor for ...

    • Growth hormone effect on body composition in Turner syndrome 

      Baldin, Alexandre Duarte; Fabbri, Tatiana [UNIFESP]; Siviero-Miachon, Adriana Aparecida [UNIFESP]; Spinola-Castro, Angela Maria [UNIFESP]; Valente de Lemos-Marini, Sofia Helena; Matias Baptista, Maria Tereza; Rodrigues D'Souza-Li, Lilia Freire; Maciel-Guerra, Andrea Trevas; Guerra-Junior, Gil (Humana Press Inc, 2011-12-01)
      This study analyzes the body composition of young adult women with Turner syndrome (TS) either treated or not treated with recombinant human growth hormone (rhGH) and compares them with a group of healthy women. Fifty-two ...

    • O hormônio de crescimento na síndrome de Turner: dados e reflexões 

      Guedes, Alexis Dourado [UNIFESP]; Bianco, Bianca Alves Vieira [UNIFESP]; Callou, Emmanuela Q. [UNIFESP]; Gomes, Ana Luíza [UNIFESP]; Lipay, Mônica V. N. [UNIFESP]; Verreschi, Ieda Therezinha do Nascimento [UNIFESP] (Sociedade Brasileira de Endocrinologia e Metabologia, 2008-07-01)
      Short stature is the major characteristic of Turner syndrome. The statural appeal is premature and become evident in the puberty. Haploinsuficiency of SHOX gene has been related as main factor on final height of these ...

    • Impacto do tratamento com GH sobre as funções tireoidiana e adrenal 

      Martins, Manoel R. A.; Abucham, Julio [UNIFESP] (Sociedade Brasileira de Endocrinologia e Metabologia, 2008-07-01)
      Somatotrophic status is a major determinant of both thyrotrophic and corticotrophic axis. In growth hormone deficient patients, somatotrophic replacement increases the conversion rate of the inactive form of the thyroid ...

    • Níveis séricos de hormônio de crescimento, fator de crescimento símile à insulina e sulfato de deidroepiandrosterona em idosos residentes na comunidade. Correlação com parâmetros clínicos 

      Huayllas, Martha K.p. [UNIFESP]; Carvalhaes Neto, Nelson [UNIFESP]; Ramos, Luiz Roberto [UNIFESP]; Kater, Claudio Elias [UNIFESP] (Sociedade Brasileira de Endocrinologia e Metabologia, 2001-04-01)
      Aging is associated with body changes, especially related with the endocrine system. The activity of the GH/IGF-1 axis and production of DHEAS decline significantly with aging, compromising body composition, cardiovascular ...

    • Novel mechanisms of growth hormone regulation: growth hormone-releasing peptides and ghrelin 

      Lengyel, Ana Maria Judith [UNIFESP] (Associação Brasileira de Divulgação Científica, 2006-08-01)
      Growth hormone secretion is classically modulated by two hypothalamic hormones, growth hormone-releasing hormone and somatostatin. A third pathway was proposed in the last decade, which involves the growth hormone ...