Browsing by Subject "Glutamate"

Now showing items 1-10 of 21

    • Alterations in Calcium Signaling and a Decrease in Bcl-2 Expression: Possible Correlation With Apoptosis in Aged Striatum 

      Ureshino, Rodrigo Portes [UNIFESP]; Bertoncini, Clelia Rejane Antonio [UNIFESP]; Fernandes, Maria Jose da Silva [UNIFESP]; Abdalla, Fernando Mauricio Francis; Porto, Catarina Segreti [UNIFESP]; Hsu, Yi-Te; Lopes, Guiomar Silva [UNIFESP]; Smaili, Soraya Soubhi [UNIFESP] (Wiley-Blackwell, 2010-02-01)
      Aging is a multifaceted process associated with various functional and structural deficits that might be evolved in degenerative diseases. It has been shown that neurodegenerative disorders are associated with alterations ...

    • Análise dos efeitos do extrato padronizado de Ginkgo biloba L. na aquisição e na extinção do medo condicionado 

      Zamberlam, Claudia Raquel [UNIFESP] (Universidade Federal de São Paulo, 2013-04-25)
      Dados anteriores no nosso laboratório mostraram que os tratamentos a curto ou a longo prazo com o extrato padronizado de Ginkgo biloba L. (EGb) modulam a aquisição da Resposta Emocional Condicionda (REC). Essas modificações ...

    • Astrócitos artificiais e biológicos em um modelo animal agudo de epilepsia 

      Oliveira, Roberto Novaes de [UNIFESP] (Universidade Federal de São Paulo, 2023-09-28)
      A epilepsia é um transtorno neurológico crônico, caracterizado pela recorrência das chamadas crises epilépticas. Crises epilépticas encontram-se associadas à atividade hipersincrônica e repetitiva de agrupamentos neuronais ...

    • Avaliação da eficácia de doses repetidas de nitroprussiato de sódio no tratamento da esquizofrenia resistente: um estudo duplo-cego, randomizado, controlado por placebo 

      Adelino, Marcelo Pinheiro Machado [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2020-08-21)
      In present study, we evaluated the efficacy of repeated-dose sodium nitroprusside (SNP) in treatment-resistant schizophrenia. Methods: This was a double-blind, randomized, placebo-controlled trial. Twenty DSM-IV schizophrenia ...

    • Changes in GABAergic inputs in the paraventricular nucleus maintain sympathetic vasomotor tone in chronic heart failure 

      Carillo, Bruno de Arruda [UNIFESP]; Oliveira-Sales, Elizabeth Barbosa de [UNIFESP]; Andersen, Monica Levy [UNIFESP]; Tufik, Sergio [UNIFESP]; Hipólide, Débora Cristina [UNIFESP]; Santos, A. A. [UNIFESP]; Tucci, Paulo José Ferreira [UNIFESP]; Bergamaschi, Cassia Toledo [UNIFESP]; Campos, Ruy Ribeiro [UNIFESP] (Elsevier B.V., 2012-11-02)
      The paraventricular nucleus (PVN) of the hypothalamus is an important region of the brain involved in the regulation of sympathetic vasomotor tone. Accumulating evidence supports the idea that a change in hypothalamic ...

    • Glutamate induces autophagy via the two-pore channels in neural cells 

      Pereira, Gustavo José da Silva [UNIFESP]; Antonioli, Manuela; Hirata, Hanako [UNIFESP]; Ureshino, Rodrigo Portes [UNIFESP]; Nascimento, Aline Rosa [UNIFESP]; Bincoletto, Claudia [UNIFESP]; Vescovo, Tiziana; Piacentini, Mauro; Fimia, Gian Maria; Smaili, Soraya Soubhi [UNIFESP] (Impact Journals Llc, 2017)
      NAADP (nicotinic acid adenine dinucleotide phosphate) has been proposed as a second messenger for glutamate in neuronal and glial cells via the activation of the lysosomal Ca2+ channels TPC1 and TPC2. However, the activities ...

    • Glutamatergic neurotransmission in the inferior colliculus influences intrastriatal haloperidol-induced catalepsy 

      Medeiros, Priscila [UNIFESP]; Viana, Milena de Barros [UNIFESP]; Silva, Regina Cláudia Barbosa da [UNIFESP]; Tonelli, Luan Castro [UNIFESP]; Melo-Thomas, Liana [UNIFESP] (Elsevier B.V., 2014-07-15)
      The inferior colliculus (IC) is an important midbrain relay station for the integration of descending and ascending auditory information. in addition, it has also been implicated in the processing of acoustic information ...

    • Hipótese glutamatérgica da esquizofrenia 

      Bressan, Rodrigo Affonseca [UNIFESP]; Pilowsky, Lyn S (Associação Brasileira de Psiquiatria - ABP, 2003-09-01)
      Schizophrenia is a devastating psychiatric disorder whose pathophysiology has not been fully clarified yet. Although dopamine dysfunction in schizophrenia is unequivocal, there are many evidences suggesting the involvement ...

    • Influence of N-methyl-D-aspartate receptors on ouabain activation of nuclear factor-kappa B in the rat hippocampus 

      Kawamoto, Elisa Mitiko; Lima, Larissa de Sá; Munhoz, Carolina Demarchi; Yshii, Lidia Mitiko; Kinoshita, Paula Fernanda; Amaral, Fernanda Gaspar; Pestana, Rafaela R. Ferrão; Orellana, Ana Maria Marques; Cipolla-Neto, Jose; Britto, Luiz Roberto Giorgetti de; Avellar, Maria Christina Werneck [UNIFESP]; Rossoni, Luciana Venturini; Scavone, Cristoforo (Wiley-Blackwell, 2012-01-01)
      It has been shown that ouabain (OUA) can activate the Na,K-ATPase complex and mediate intracellular signaling in the central nervous system (CNS). Inflammatory stimulus increases glutamatergic transmission, especially at ...

    • Influência da neurotransmissão espinal sobre o tônus vasomotor simpático no modelo de hipertensão renovascular 

      Milanez, Maycon Igor De Oliveira [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2017-09-28)
      Previous studies showed a higher glutamate and angiotensin II (ANG II) receptors activation in the rostral ventrolateral medulla (RVLM) that may lead to sympathoexcitationin renovascular hypertensive rats (2K-1C). However, ...