Now showing items 1-10 of 71

    • Acid invertase as a serious candidate to control the balance sucrose versus (glucose plus fructose) of banana fruit during ripening 

      Fils-Lycaon, Bernard; Julianus, Philippe; Chillet, Marc [UNIFESP]; Galas, Colette; Hubert, Olivier; Rinaldo, Dominique; Mbeguie-A-Mbeguie, Didier (Elsevier B.V., 2011-06-10)
      Six banana varieties: 3 'dessert' ones: 'IDN 110'; 'Kirun'; and 'Grande Naine', and 3 'cooking' ones: 'Galeo'; 'Sowmuk'; and 'French' were used to investigate the relationship between sugar profiles and activities of ...

    • Adult exposure to bisphenol A (BPA) in Wistar rats reduces sperm quality with disruption of the hypothalamic-pituitary-testicular axis 

      Wisniewski, Patricia; Romano, Renata M.; Kizys, Marina M. L. [UNIFESP]; Oliveira, Kelen C. [UNIFESP]; Kasamatsu, Teresa [UNIFESP]; Giannocco, Gisele [UNIFESP]; Chiamolera, Maria I. [UNIFESP]; Dias-da-Silva, Magnus R. [UNIFESP]; Romano, Marco A. (Elsevier B.V., 2015-03-02)
      Reproductive physiology involves complex biological processes that can be disrupted by exposure to environmental contaminants. the effects of bisphenol A (BPA) on spermatogenesis and sperm quality is still unclear. the ...

    • Altered myocardial metabolic adaptation to increased fatty acid availability in cardiomyocyte-specific CLOCK mutant mice 

      Peliciari-Garcia, Rodrigo Antonio [UNIFESP]; Goel, Mehak; Aristorenas, Jonathan A.; Shah, Krishna; He, Lan; Yang, Qinglin; Shalev, Anath; Bailey, Shannon M.; Prabhu, Sumanth D.; Chatham, John C.; Gamble, Karen L.; Young, Martin E. (Elsevier Science Bv, 2016)
      A mismatch between fatty acid availability and utilization leads to cellular/organ dysfunction during cardiometabolic disease states (e.g., obesity, diabetes mellitus). This can precipitate cardiac dysfunction. The heart ...

    • Analysis of Gene Expression in the Endocervical Epithelium of Women With Deep Endometriosis 

      Kopelman, Alexander [UNIFESP]; Girão, Manoel João Batista Castello [UNIFESP]; Bonetti, Tatiana Carvalho de Souza [UNIFESP]; Carvalho, Cristina Valletta de [UNIFESP]; Silva, Ismael Dale Cotrim Guerreiro da [UNIFESP]; Schor, Eduardo [UNIFESP] (Sage Publications Inc, 2016)
      Endometriosis affects approximately 12% of reproductive-age women and is currently diagnosed using invasive laparoscopic surgery. Differences in gene expression in the eutopic endometrium between women with and without ...

    • Analysis of KIAA1549-BRAF fusion gene expression and IDH1/IDH2 mutations in low grade pediatric astrocytomas 

      Rampazzo, Gabriela Cruz [UNIFESP]; Oliveira, Indhira Dias [UNIFESP]; Moraes, Lais [UNIFESP]; Paniago, Mario Del Giudice [UNIFESP]; Seixas Alves, Maria Teresa de [UNIFESP]; Capellano, Andrea Maria [UNIFESP]; Silva, Nasjla Saba da [UNIFESP]; Cavalheiro, Sergio [UNIFESP]; Cerutti, Janete Maria [UNIFESP]; Toledo, Silvia Regina Caminada de [UNIFESP] (Springer, 2014-04-01)
      Low-grade astrocytomas comprise about 30 % of the central nervous system tumors in children. Several investigations have searched a correlation between the BRAF gene fusions alterations and mutations at IDH1 and IDH2 genes ...

    • Análise de dados de expressão gênica e proteica da ARHGAP21 em câncer de próstata associada com dados clínicos 

      Silva, Jeyson Pereira da [UNIFESP] (Universidade Federal de São Paulo, 2018-12-11)
      O câncer de próstata (CaP) é a segunda neoplasia mais prevalente nos homens em todo o mundo. Majoritariamente, é uma doença que afeta indivíduos de países com baixos índices-sócio-econômicos e em desenvolvimento, incluindo ...

    • ASPM gene expression in medulloblastoma 

      Vulcani-Freitas, Tânia Maria [UNIFESP]; Saba-Silva, Najsla [UNIFESP]; Cappellano, Andrea [UNIFESP]; Cavalheiro, Sergio [UNIFESP]; Marie, Sueli K. N.; Oba-Shinjo, Sueli M.; Malheiros, Suzana M. F. [UNIFESP]; Toledo, Silvia Regina Caminada de [UNIFESP] (Springer, 2011-01-01)
      Medulloblastomas are the most common malignant tumors of the central nervous system in childhood. the incidence is about 19-20% between children younger than 16 years old with peak incidence between 4 and 7 years. Despite ...

    • Atividade quimioprotetora do extrato de maçã na carcinogênese bucal quimicamente induzida pela 4-nitroquinolina 1-óxido em ratos 

      Ribeiro, Flavia Andressa Pidone [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2014-09-23)
      Head and neck cancers represent 10% of malignant tumors, and approximately 40% of them are located in the oral cavity. In Brazil oral cancer, is considered the sixth most frequent types in men and the eight most common in ...

    • Clinical implication of 14-3-3 epsilon expression in gastric cancer 

      Leal, Mariana Ferreira [UNIFESP]; Calcagno, Danielle Queiroz [UNIFESP]; Demachki, Samia; Assumpcao, Paulo Pimentel; Chammas, Roger; Burbano, Rommel Rodriguez; Smith, Marilia de Arruda Cardoso [UNIFESP] (Baishideng Publishing Group Inc, 2012-04-07)
      AIM: To evaluate for the first time the protein and mRNA expression of 14-3-3 epsilon in gastric carcinogenesis.METHODS: 14-3-3 epsilon protein expression was determined by western blotting, and mRNA expression was examined ...

    • Clinical significance of molecular alterations in histologically negative surgical margins of head and neck cancer patients 

      Carvalho, Ana Carolina de [UNIFESP]; Kowalski, Luiz Paulo [UNIFESP]; Campos, Antônio Hugo José Fróes Marques; Soares, Fernando Augusto; Carvalho, André Lopes; Vettore, Andre Luiz [UNIFESP] (Elsevier B.V., 2012-03-01)
      The development of locoregional recurrence is the main reason for treatment failure in head and neck squamous cell carcinomas (HNSCC) and the remaining of tumor cells in surgical margins is associated with recurrence. ...