Browsing by Subject "GPI"

CHARACTERIZATION OF A PHOSPHOLIPASE C-RESISTANT INOSITOL CONTAINING GLYCOLIPID FROM TRYPANOSOMA-CRUZI

Heise, Norton [UNIFESP]; Raper, J.; Cardosodealmeida, M. L. (Assoc Bras Divulg Cientifica, 1994-02-01)

Since glycosylphosphatidylinositol is the most common form of attachment of proteins to membranes in T. cruzi, and that this parasite depends on surface-mediated interactions for survival within the vector and mammalian ...

FURTHER CHARACTERIZATION OF THE ACIDIC GPI-HYDROLYZING PHOSPHOLIPASE PRESENT IN HUMAN SERA

Stambuk, Boris Juan Carlos Ugarte [UNIFESP]; Cardosodealmeida, M. L. (Assoc Bras Divulg Cientifica, 1994-02-01)

A phospholipase from human serum capable of hydrolyzing glycosylphosphatidylinositol membrane anchors was described and partially characterized by our group some years ago. This activity presented a pH optimum between 5.0 ...

The mucin-like glycoprotein super-family of Trypanosoma cruzi: structure and biological roles

Acosta-Serrano, A.; Almeida, I. C.; Freitas, L. H.; Yoshida, N.; Schenkman, S. (Elsevier B.V., 2001-05-01)

Trypanosoma cruzi expresses at its surface large amounts of mucin-like glycoproteins. the T. cruzi mucins (TcMUC), a group of highly glycosylated GPI-anchored proteins rich in Thr, Ser, and Pro residues, are expressed in ...

Phosphatidylinositol-specific phospholipase C (PI-PLC) cleavage of GPI-anchored surface molecules of Trypanosoma cruzi triggers in vitro morphological reorganization of trypomastigotes

Mortara, R. A.; Minelli, LMS; Vandekerchove, F.; Nussenzweig, V; Ramalho-Pinto, F. J. (Soc Protozoologists, 2001-01-01)

Trypanosoma cruzi trypomastigotes treated with phosphatidylinositol-specific phospholipase C (PI-PLC) in vitro are rapidly induced to differentiate into round forms. Using confocal microscopy, we were able to show that ...