Browsing by Subject "Fukugetin"

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    • Inhibition of cysteine proteases by a natural biflavone: behavioral evaluation of fukugetin as papain and cruzain inhibitor 

      Assis, Diego Magno [UNIFESP]; Gontijo, Vanessa Silva; Pereira, Ivan de Oliveira; Santos, Jorge Alexandre Nogueira [UNIFESP]; Camps, Ihosvany; Nagem, Tanus Jorge; Ellena, Javier; Izidoro, Mario Augusto [UNIFESP]; Tersariol, Ivarne Luis dos Santos [UNIFESP]; Barros, Nilana Meza Tenório de [UNIFESP]; Doriguetto, Antonio Carlos; Santos, Marcelo Henrique dos; Juliano, Maria Aparecida [UNIFESP] (Informa Healthcare, 2013-08-01)
      Cruzain is the major cysteine protease of Trypanosoma cruzi, the infectious agent responsible for Chagas disease, and cruzain inhibitors display considerable antitrypanosomal activity. in the present work we elucidated ...