Browsing by Subject "F359I point mutation"

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    • Dasatinib Overrides Imatinib Resistance Mediated by the F359I Residue Mutation in Two Patients with Chronic Myeloid Leukemia 

      Serpa, Mariana [UNIFESP]; Sanabani, Sabri S. [UNIFESP]; Dorlhiac-Llacer, Pedro Enrique; Nardinelli, Luciana; Ferreira, Patricia de Barros; Borges Martins, Thays Fernanda; Seguro, Fernanda [UNIFESP]; Bendit, Israel (Karger, 2012-01-01)
      Despite the beneficial effects of imatinib mesylate, some patients may either not respond or respond suboptimally. Here, we report two chronic myelogenous leukemia patients; one had a suboptimal response according to ...