Browsing by Subject "Epilepsy"
Now showing items 1-10 of 157
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Absence-like seizures in adult rats following pilocarpine-induced status epilepticus early in life
(Associação Brasileira de Divulgação Científica, 2003-12-01)Administration of pilocarpine causes epilepsy in rats if status epilepticus (SE) is induced at an early age. To determine in detail the electrophysiological patterns of the epileptogenic activity in these animals, 46 Wistar ...
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Alterações neuroendócrinas e moleculares associadas ao sistema hipotálamo neuro-hipofisário em ratos Wistar audiogênicos submetidos a estímulos acústicos crônicos
(Universidade Federal de São Paulo (UNIFESP), 2020-12-18)The Wistar Audiogenic Rat (WAR) is an animal model of epilepsy that, when submitted to chronic acoustic stimuli (audiogenic kindling), may present activation of mesencephalic structures and recruitment of limbic structures. ...
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Alterações plásticas da epileptogênese com ênfase na reorganização colinérgica
(Universidade Federal de São Paulo (UNIFESP), 2006-01-01)Purpose: We investigated whether the administration of scopolamine, has the ability to interfere in the epileptogenic process and whether this effect could be explained by plastic changes in the cholinergic system. Methods: ...
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Alteration of purinergic P2X(4) and P2X(7) receptor expression in rats with temporal-lobe epilepsy induced by pilocarpine
(Elsevier B.V., 2009-02-01)Although ATP and P2X receptor activity have been lately associated with epilepsy, little is known regarding their exact roles in epileptogenesis. Temporal-lobe epilepsy (TLE) in rat was induced by pilocarpine in order to ...
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Altered MT1 and MT2 melatonin receptors expression in the hippocampus of pilocarpine-induced epileptic rats
(Academic Press Inc Elsevier Science, 2017)Clinical and experimental findings show that melatonin may be used as an adjuvant to the treatment of epilepsy related complications by alleviates sleep disturbances, circadian alterations and attenuates seizures alone or ...
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Altered sleep regulation in a mouse model of SCN1A-derived genetic epilepsy with febrile seizures plus (GEFS+)
(Wiley-Blackwell, 2013-04-01)Purpose Mutations in the voltage-gated sodium channel (VGSC) gene SCN1A are responsible for a number of epilepsy disorders, including genetic epilepsy with febrile seizures plus (GEFS+) and Dravet syndrome. in addition to ...
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Analysis of clinical characteristics and risk factors for mortality in human status epilepticus
(W B Saunders Co Ltd, 2003-09-01)Purpose: To analyse clinical data including aetiology, age, antecedents, classification and mortality in human status epilepticus (SE), and to assess prognostic factors for mortality.Methods: A prospective study was ...
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Análise da expressão das proteínas ARC e HOMER1A no modelo de epilepsia do lobo frontal induzido por pilocarpina
(Universidade Federal de São Paulo (UNIFESP), 2009) -
Análise das respostas cardiovasculares em ratos submetidos ao modelo do abrasamento elétrico da amígdala
(Universidade Federal de São Paulo (UNIFESP), 2011-04-27)Objetivo: As alterações cardiovasculares podem contribuir para a morte súbita e inesperada em epilepsia (SUDEP). Com o intuito de verificar as possíveis alterações cardiovasculares que ocorrem durante a epileptogênese, ...
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Análise qualitativa e quantitativa das narrativas de pessoas com Epilepsia
(Universidade Federal de São Paulo (UNIFESP), 2019-11-20)Purpose: The purpose of this study was to analyze how people with two well-defined epilepsies, mesial temporal lobe epilepsy related to hippocampal sclerosis (MTLE/HS) and juvenile myoclonic epilepsy (JME), give meaning ...