Browsing by Subject "ENDOCYTOSIS"

Now showing items 1-4 of 4

    • PLASMA KALLIKREIN and THROMBIN ARE CLEARED THROUGH UNRELATED HEPATIC PATHWAYS 

      Loureirosilva, M. R.; Kouyoumdjian, M.; Borges, D. R. (Rapid Science Publishers, 1993-08-01)
      Plasma kallikrein (PK) and thrombin (TH), serine proteinases formed from inactive precursors, participate in important body defence mechanisms. the isolated hepatocyte recognizes TH, and the liver clears PK by calcium-independent ...

    • PLASMA KALLIKREIN CLEARANCE BY the LIVER of CHRONIC CARBON TETRACHLORIDE-TREATED RATS 

      Toledo, C. F.; Kouyoumdjian, M.; Lanzoni, V. P.; Borges, D. R. (Blackwell Science Publ Austr, 1995-03-01)
      We have previously reported that the endocytosis of rat plasma kallikrein (RPK) by hepatocytes is a calcium-independent and beta-galactoside-dependent mechanism. We now report the clearance of RPK by the liver of four ...

    • PLASMA, KALLIKREIN CLEARANCE BY THE LIVER - A REVIEW 

      Borges, Durval Rosa [UNIFESP]; Kouyoumdjian, Maria [UNIFESP] (Assoc Bras Divulg Cientifica, 1994-08-01)
      1. The liver is the main organ clearing both plasma and tissue kallikreins from the circulation. Hepatocytes are responsible for the internalization of rat plasma kallikrein (RPK) and the clearance of plasma kallikrein by ...

    • THE RECOGNITION SITE for HEPATIC-CLEARANCE of PLASMA KALLIKREIN IS ON ITS HEAVY-CHAIN and IS LATENT ON PROKALLIKREIN 

      Borges, D. R.; Kouyoumdjian, M. (Munksgaard Int Publ Ltd, 1992-09-01)
      We partially purified the glycoproteins prokallikrein and kallikrein from rat plasma. the purification of rat plasma kallikrein may result in two forms: an intact form (alpha, M(r) 84-87 kDa) and a partially degraded form ...