Browsing by Subject "EAE"
Now showing items 1-3 of 3
-
GCN2 kinase plays an important role triggering the remission phase of experimental autoimmune encephalomyelitis (EAE) in mice
(Elsevier B.V., 2014-03-01)Experimental autoimmune encephalomyelitis (EAE) has been widely employed as a model to study multiple sclerosis (MS) and indeed has allowed some important advances in our comprehension of MS pathogenesis. Several pieces ...
-
Oral tolerance reduces Th17 cells as well as the overall inflammation in the central nervous system of EAE mice
(Elsevier B.V., 2010-10-08)Multiple sclerosis (MS) is an autoimmune disease characterized by inflammatory immune response directed against myelin antigens of the central nervous system. in its murine model, EAE, Th17 cells play an important role in ...
-
The role of kinin B-1 and B-2 receptors in the persistent pain induced by experimental autoimmune encephalomyelitis (EAE) in mice: Evidence for the involvement of astrocytes
(Elsevier B.V., 2013-06-01)Multiple sclerosis (MS) is a progressive, demyelinating inflammatory disease of the human central nervous system (CNS). While the primary symptoms of MS affect motor function, it is now recognized that chronic pain is a ...
