Now showing items 1-10 of 15

    • Absence of peripheral blood mononuclear cells priming in hemodialysis patients 

      Santos, B.c. [UNIFESP]; Starobinas, N.; Barbuto, J.a.m.; Russo, M.; Schor, Nestor [UNIFESP] (Associação Brasileira de Divulgação Científica, 2003-02-01)
      As a consequence of the proinflammatory environment occurring in dialytic patients, cytokine overproduction has been implicated in hemodialysis co-morbidity. However, there are discrepancies among the various studies that ...

    • Aspectos histomorfológicos e respiratórios em modelo de lesão pulmonar aguda por sepse em ratos tratados com pentoxifilina 

      Oliveira, Wagner Rogerio Souza de [UNIFESP]; Cavassani, Sâmia Santos [UNIFESP]; Maganhin, Carla Cristina [UNIFESP]; Carbonel, Adriana Aparecida Ferraz [UNIFESP]; Simões, Manuel de Jesus [UNIFESP]; Simões, Ricardo Santos [UNIFESP]; Junqueira, Virginia Berlanga Campos [UNIFESP]; Oliveira-Júnior, Itamar Souza [UNIFESP] (Associação Médica Brasileira, 2009-01-01)
      OBJECTIVE: Respiratory repercussion on acute lung injury in a model of induced sepsis intraperitoneally. METHODS: Fifteen animals taken at random were submitted to adult male Wistar rats. The rats were randomly divided ...

    • Cytokine genotyping in preeclampsia 

      Daher, S.; Sass, N.; Oliveira, L. G.; Mattar, Rosiane [UNIFESP] (Blackwell Publishing, 2006-02-01)
      ProblemConsidering that cytokines are involved in preeclampsia (PE) pathogenesis and that cytokine gene polymorphism may affect cytokine production, our purpose was to investigate the association of PE with tumor necrosis ...

    • Effects of pentoxifylline on TNF-alpha and lung histopathology in HCL-induced lung injury 

      Oliveira-Júnior, Itamar Souza [UNIFESP]; Maganhin, Carla Cristina [UNIFESP]; Carbonel, Adriana Aparecida Ferraz [UNIFESP]; Monteiro, Cristina Maria Rodrigues [UNIFESP]; Cavassani, Sâmia Santos [UNIFESP]; Oliveira-filho, Ricardo Martins [UNIFESP] (Faculdade de Medicina / USP, 2008-01-01)
      OBJECTIVE: To evaluate the effects of pentoxifylline on hydrochloric acid-induced lung lesions in rats subjected to mechanical ventilation. METHODS: Twenty male, adult Wistar-EPM-1 rats were anesthetized and randomly grouped ...

    • Exercise training changes IL-10/TNF-alpha ratio in the skeletal muscle of post-MI rats 

      Batista, M. L.; Rosa, J. C. [UNIFESP]; Lopes, R. D. [UNIFESP]; Lira, F. S.; Martins, E.; Yamashita, A. S.; Brum, P. C.; Lancha, A. H.; Lopes, A. C. [UNIFESP]; Seelaender, M. (Elsevier B.V., 2010-01-01)
      Heart failure (HF) is associated with changes in the skeletal muscle (SM) which might be a consequence of the unbalanced local expression of pro- (TNF-alpha) and anti- (IL-10) inflammatory cytokines, leading to ...

    • Exercise-induced hippocampal anti-inflammatory response in aged rats 

      Silva, Sergio Gomes da [UNIFESP]; Simoes, Priscila Santos Rodrigues [UNIFESP]; Mortara, Renato Arruda [UNIFESP]; Scorza, Fulvio Alexandre [UNIFESP]; Cavalheiro, Esper Abrão [UNIFESP]; Naffah-Mazzacoratti, Maria da Graca [UNIFESP]; Arida, Ricardo Mario [UNIFESP] (Biomed Central Ltd, 2013-05-10)
      Aging is often accompanied by cognitive decline, memory impairment and an increased susceptibility to neurodegenerative disorders. Most of these age-related alterations have been associated with deleterious processes such ...

    • Moderate exercise increases the metabolism and immune function of lymphocytes in rats 

      Navarro, Francisco; Nova Bacurau, Aline Villa; Pereira, Guilherme Borges; Araujo, Ronaldo Carvalho [UNIFESP]; Almeida, Sandro Soares [UNIFESP]; Moraes, Milton Rocha [UNIFESP]; Uchida, Marco Carlos; Pereira Costa Rosa, Luis Fernando Bicudo; Navalta, James; Prestes, Jonato; Pereira Bacurau, Reury Frank (Springer, 2013-05-01)
      Exercise modulates both glucose and glutamine metabolism which influences lymphocyte function. We investigated the influence of chronic moderate exercise on glucose and glutamine metabolism in lymphocytes, the associated ...

    • Molecular mechanisms of cardiac electromechanical remodeling during Chagas disease: Role of TNF and TGF-beta 

      Cruz, Jader Santos; Machado, Fabiana Simao; Ropert, Catherine; Roman-Campos, Danilo [UNIFESP] (Elsevier Science London, 2017)
      Chagas disease is caused by the trypanosomatid Trypanosoma cruzi, which chronically causes heart problems in up to 30% of infected patients. Chagas disease was initially restricted to Latin America. However, due to migratory ...

    • Nervous and immune systems signals and connections: Cytokines in hippocampus physiology and pathology 

      Arisi, Gabriel Maisonnave [UNIFESP] (Elsevier B.V., 2014-09-01)
      Signaling through secretion of small molecules is a hallmark of both nervous and immune systems. the scope and influence of the intense message exchange between these two complex systems are only now becoming objects of ...

    • Paracoccidioides brasiliensis induces cytokine secretion in epithelial cells in a protease-activated receptor-dependent (PAR) manner 

      de Oliveira, Priscila [UNIFESP]; Juliano, Maria Aparecida [UNIFESP]; Tanaka, Aparecida Sadae [UNIFESP]; Carmona, Adriana Karaoglanovic [UNIFESP]; Batista dos Santos, Saara Maria [UNIFESP]; Silva Campitelli de Barros, Bianca Carla [UNIFESP]; Maza, Paloma Korehisa [UNIFESP]; Puccia, Rosana [UNIFESP]; Suzuki, Erika [UNIFESP] (Springer, 2017)
      Paracoccidioides brasiliensis is one of the etiological agents of the human systemic mycosis paracoccidioidomycosis. Protease-activated receptors (PARs) are expressed in many cell types and comprise a family of G protein-coupled ...