Now showing items 1-3 of 3

    • Cytogenetics, JAK2 and MPL mutations in polycythemia vera, primary myelofibrosis and essential thrombocythemia 

      Santos, Leonardo Caires dos [UNIFESP]; Ribeiro, Juliana Corrêa da Costa [UNIFESP]; Silva, Neusa Pereira da [UNIFESP]; Cerutti, Janete Maria [UNIFESP]; Silva, Maria Regina Regis da [UNIFESP]; Chauffaille, Maria de Lourdes Lopes Ferrari [UNIFESP] (Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular, 2011-12-01)
      BACKGROUND: The detection of molecular and cytogenetic alterations is important for the diagnosis, prognosis and classification of myeloproliferative neoplasms. OBJECTIVE: The aim of this study was to detect the following ...

    • Different Conformation of Two Supernumerary 18p Isochromosomes, One with a Concomitant Partial 18q Trisomy 

      Dutra, Ana Rosa Noronha [UNIFESP]; Mancini, Tatiane Iris [UNIFESP]; Takeno, Sylvia Satomi [UNIFESP]; Oliveira, Marcio Moyses de [UNIFESP]; Kim, Chong A.; Perez, Ana Beatriz Alvarez [UNIFESP]; Kulikowski, Leslie Domenici [UNIFESP]; Melaragno, Maria Isabel [UNIFESP] (Karger, 2012-01-01)
      The presence of a supernumerary 18p isochromosome is a rare chromosomal abnormality that results in 18p tetrasomy. This is a report on the clinical, cytogenetic and molecular findings of 2 non-related patients with a ...

    • Prevalence of FMS-like tyrosine kinase 3/internal tandem duplication (FLT3/ITD+) in de novo acute myeloid leukemia patients categorized according to cytogenetic risk 

      Krum, Everson Augusto; Yamamoto, Mihoko [UNIFESP]; Chauffaille, Maria de Lourdes Lopes Ferrari [UNIFESP] (Associação Paulista de Medicina - APM, 2009-01-01)
      CONTEXT AND OBJECTIVE: The mechanism involved in leukemogenesis remains unclear and more information about the disruption of the cell proliferation, cell differentiation and apoptosis of neoplastic cells is required. DESIGN ...