Now showing items 1-5 of 5

    • Boophilus microplus cathepsin L-like (BmCL1) cysteine protease: Specificity study using a peptide phage display library 

      Clara, Renan Orsati [UNIFESP]; Soares, Tatiane Sanches [UNIFESP]; Torquato, Ricardo Jose Soares [UNIFESP]; Lima, Cassia Arantes de [UNIFESP]; Watanabe, Renata Midori Okuta [UNIFESP]; Barros, Nilana Meza Tenório de [UNIFESP]; Carmona, Adriana Karaoglanovic [UNIFESP]; Masuda, Aoi; Vaz Junior, Itabajara S.; Tanaka, Aparecida Sadae [UNIFESP] (Elsevier B.V., 2011-09-27)
      The tick Rhipicephalus (Boophilus) microplus is one of the most important bovine ectoparasites, a disease vector responsible for losses in meat and milk productions. A cysteine protease similar to cathepsin L, named BmCL1, ...

    • Characterization of a novel cystatin type 2 from Rhipicephalus microplus midgut 

      Cardoso, Thyago H. S. [UNIFESP]; Lu, Stephen [UNIFESP]; Gonzalez, Boris R. G. [UNIFESP]; Torquato, Ricardo J. S. [UNIFESP]; Tanaka, Aparecida S. [UNIFESP] (Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)
      The Rhipicephalus (Boophilus) microplus is an exclusive bovine ectoparasite responsible for the transmission of pathogens that decrease meat, leather and milk productions. Cattle vaccination is an alternative to control ...

    • Corneal angiogenesis modulation by cysteine cathepsins: in vitro and in vivo studies 

      Coppini, Larissa Pereira [UNIFESP]; Visniauskas, Bruna [UNIFESP]; Costa, Elaine F.; Filho, Milton N. [UNIFESP]; Rodrigues, Eduardo B. [UNIFESP]; Chagas, Jair R. [UNIFESP]; Farah, Michel E. [UNIFESP]; Barros, Nilana M. T. [UNIFESP]; Carmona, Adriana K. [UNIFESP] (Elsevier B.V., 2015-05-01)
      Corneal avascularization is essential for normal vision. Several antiangiogenic factors were identified in cornea such as endostatin and angiostatin. Cathepsin V, which is highly expressed in the cornea, can hydrolyze human ...

    • Inhibition of cysteine proteases by a natural biflavone: behavioral evaluation of fukugetin as papain and cruzain inhibitor 

      Assis, Diego Magno [UNIFESP]; Gontijo, Vanessa Silva; Pereira, Ivan de Oliveira; Santos, Jorge Alexandre Nogueira [UNIFESP]; Camps, Ihosvany; Nagem, Tanus Jorge; Ellena, Javier; Izidoro, Mario Augusto [UNIFESP]; Tersariol, Ivarne Luis dos Santos [UNIFESP]; Barros, Nilana Meza Tenório de [UNIFESP]; Doriguetto, Antonio Carlos; Santos, Marcelo Henrique dos; Juliano, Maria Aparecida [UNIFESP] (Informa Healthcare, 2013-08-01)
      Cruzain is the major cysteine protease of Trypanosoma cruzi, the infectious agent responsible for Chagas disease, and cruzain inhibitors display considerable antitrypanosomal activity. in the present work we elucidated ...

    • Tooth Bleaching Increases Dentinal Protease Activity 

      Sato, Claudio Tadaaki; Rodrigues, F. A.; Garcia, Daniel Moreno; Vidal, Cristina de Mattos Pimenta; Pashley, David H.; Tjaderhane, Leo; Carrilho, Marcela Rocha de Oliveira; Nascimento, Fábio Dupart; Tersariol, Ivarne Luis dos Santos [UNIFESP] (Sage Publications Inc, 2013-02-01)
      Hydrogen peroxide is an oxidative agent commonly used for dental bleaching procedures. the structural and biochemical responses of enamel, dentin, and pulp tissues to the in vivo bleaching of human (n = 20) premolars were ...