Now showing items 1-4 of 4

    • Chronic myeloid leukemia (CML): prognostic factors and survival analysis 

      Colleoni, Gisele Wally Braga [UNIFESP]; Chauffaille, Maria de Lourdes Lopes Ferrari [UNIFESP]; Moncau, José Eduardo Cajado [UNIFESP]; Souto, Elizabeth Xisto [UNIFESP]; Silva, Maria Regina Regis [UNIFESP]; Kerbauy, José [UNIFESP] (Associação Paulista de Medicina - APM, 1996-02-01)
      The prognostic value of different factors upon diagnosis of CML was analysed in 45 Philadelphia (Ph1)-positive patients. The median survival was 48 months. Univariate analysis showed 5 poor prognostic factors (male sex, ...

    • Leucemia Mielóide Crônica em pediatria: perspectivas atuais 

      Lee, Maria Lúcia de Martino [UNIFESP] (Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular, 2008-04-01)
      Chronic myeloid leukemia (CML) is a rare event in childhood, comprising of less than 5% of all leukemia cases in this age group. CML is characterized by the presence of a specific molecular marker, the Ph+ chromosome, which ...

    • Modulação do eixo PLCγ1, Ca2+/CAMKII e PKC em células de leucemia mieloide crônica tratadas com violaceína 

      Miura, Natalia Tamagusko [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2020-07-30)
      Violacein is an indole derivative isolated from Chromobacterium violaceum with potential antitumor activity and specific mechanisms of action in vitro and in vivo. This compound was evaluated in vitro in cultures of chronic ...

    • Perfil proteolítico de células de leucemia mielóide crônica 

      Amador, Fernanda Cardoso [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2020-07-30)
      Objective: Identification and differentiation of protease classes present in Chronic Myeloid Leukemia cells (K562 and Lucena 1) by studying the interference of pH and variation of enzymatic substrates on their proteolytic ...