Now showing items 1-8 of 8

    • Altered of apoptotic markers of both extrinsic and intrinsic pathways induced by hepatitis C virus infection in peripheral blood mononuclear cells 

      Albertoni, Guilherme [UNIFESP]; Arnoni, Carine Prisco; Latini, Flavia Roche Moreira; Andrade, Sheila Siqueira [UNIFESP]; Araujo, Patricia Regina Barboza; Rodrigues, Flaviane Kesia; Rozenchan, Patricia Bortman [UNIFESP]; Mendes-Correa, Maria Cassia; Leite, Olavo Henrique Munhoz; Schor, Nestor [UNIFESP]; Girão, Manoel João Batista Castello [UNIFESP]; Barreto, Jose Augusto (Biomed Central Ltd, 2012-12-20)
      Background: Chronic hepatitis C (CHC) has emerged as a leading cause of cirrhosis in the U. S. and across the world. To understand the role of apoptotic pathways in hepatitis C virus (HCV) infection, we studied the mRNA ...

    • The effects of pentoxifylline into the kidneys of rats in a model of unilateral hindlimb ischemia/reperfusion injury 

      Teruya, Roberto; Fagundes, Djalma José [UNIFESP]; Oshima, Celina Tizuko Fujiyama [UNIFESP]; Brasileiro, José Lacerda; Marks, Guido; Ynouye, Celso Massachi; Simões, Manuel de Jesus [UNIFESP] (Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2008-02-01)
      PURPOSE: To study the role of pentoxifylline (PTX) on remote kidney injury caused by muscle ischemia of left hindlimb of rats. METHODS: After xylazine and ketamine anesthesia, the left hindlimb of rats (n=66) were submitted ...

    • Existe efeito protetor da oxigenação hiperbárica em retalhos cutâneos randômicos?: um estudo imuno-histoquímico de apoptose celular e fator de crescimento vascular endotelial 

      Rocha, Fernando Passos da [UNIFESP]; Fagundes, Djalma José [UNIFESP]; Pires, Jefferson André; Rocha, Fernanda Salim Testa da (Sociedade Brasileira de Cirurgia Plástica, 2013-06-01)
      BACKGROUND: Hyperbaric oxygenation (HBO) therapy aims to increase oxygen tissue pressure by at least 10 times and decrease the adverse effects of ischemia. The aim of this study was to investigate the effect of HBO on the ...

    • Expressão de topoisomerase II alfa e de caspase-3 ativada em lesão intra-epitelial cervical escamosa de baixo grau 

      Coelho, Raquel Autran [UNIFESP] (Universidade Federal de São Paulo, 2008-03-26)
      Purpose: To evaluate the correlation between the expression of topoisomerase II alpha, active caspase-3 and infection with human papillomavirus in low-grade cervical intraepithelial lesion and in the normal cervix, and ...

    • Fas, FasL, and cleaved caspases 8 and 3 in glioblastomas: A tissue microarray-based study 

      Saggioro, Fabiano Pinto; Neder, Luciano; Stávale, João Norberto [UNIFESP]; Paixão-Becker, Aline Nazareth de Paiva; Malheiros, Suzana Maria Fleury [UNIFESP]; Soares, Fernando Augusto; Pittella, José Eymard Homem; Matias, Caio César Marconato Simões; Colli, Benedicto Oscar; Carlotti Junior, Carlos Gilberto; Franco, Marcello Fabiano de [UNIFESP] (Elsevier B.V., 2014-01-01)
      This investigation analyzed the immunoexpression of FasL, Fas, cleaved caspase-8, and cleaved caspase-3 in glioblastomas. Formalin-fixed and paraffin-embedded glioblastoma tissues and control brain tissues from 97 patients ...

    • Imunoexpressão das proteínas COX-2, p53 e caspase-3 em adenoma colorretal e mucosa não neoplásica 

      Nogueira, Renan Brito [UNIFESP]; Pires, Andréa Rodrigues Cordovil; Soares, Thélia Maria Santos; Rodrigues, Simone Rabello De Souza; Campos, Mariane Antonieta Menino; Toloi, Giovanna Canato; Waisberg, Jaques (Instituto Israelita de Ensino e Pesquisa Albert Einstein, 2013-12-01)
      OBJECTIVE: To analyze the immunoexpression of the COX-2, p53, and caspase-3 proteins in colorectal adenomas and non-neoplastic mucosa. METHODS: 72 individuals were subjected to colonoscopy, which provided 50 samples of ...

    • Papel da proteína Galectina-3 no dano causado sobre o epitélio pigmentar da retina pela exposição à Luz Ultravioleta A 

      Andrade, Frans Eberth Costa [UNIFESP] (Universidade Federal de São Paulo, 2022-06-13)
      Introdução: Várias moléculas inflamatórias têm sido propostas como biomarcadores da degeneração macular relacionada à idade (DMRI), especialmente a galectina-3 (Gal-3), uma proteína altamente expressa e secretada pelas ...

    • Sildenafil citrate protects skeletal muscle of ischemia-reperfusion injury: immunohistochemical study in rat model 

      Armstrong, Dinani Matoso Fialho de Oliveira; Armstrong, Anderson da Costa; Figueiredo, Regina Célia Bressan Queiroz; Florentino, Joao Eduardo; Saad, Paulo Fernandes [UNIFESP]; Fox-Talbot, Karen; Halushka, Marc Kenneth; Berkowitz, Dan E.; Taha, Murched Omar [UNIFESP]; Fagundes, Djalma José [UNIFESP] (Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2013-04-01)
      PURPOSE: To investigate the effect of sildenafil citrate (SC) on skeletal muscle ischemia-reperfusion (IR) injury in rats. METHODS: Adult male Wistar rats were randomized into three groups: vehicle-treated control (CTG), ...