Now showing items 1-6 of 6

    • Dexamethasone-induced cardiac deterioration is associated with both calcium handling abnormalities and calcineurin signaling pathway activation 

      Guimaraes, Fabiana de Salvi [UNIFESP]; Moraes, Wilson Max Almeida Monteiro de [UNIFESP]; Marchesi Bozi, Luis Henrique; Souza, Pamela R.; Antonio, Ednei Luiz [UNIFESP]; Bocalini, Danilo Sales [UNIFESP]; Tucci, Paulo José Ferreira [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP]; Brum, Patricia Chakur; Medeiros, Alessandra [UNIFESP] (Springer, 2017)
      Dexamethasone is a potent and widely used anti-inflammatory and immunosuppressive drug. However, recent evidences suggest that dexamethasone cause pathologic cardiac remodeling, which later impairs cardiac function. The ...

    • Effects of nandrolone and resistance training on the blood pressure, cardiac electrophysiology, and expression of atrial beta-adrenergic receptors 

      das Neves, Vander Jose; Tanno, Ana Paula; Cunha, Tatiana Sousa [UNIFESP]; Fernandes, Tiago; Guzzoni, Vinicius; Silva, Carlos Alberto da; Oliveira, Edilamar Menezes de; Costa Sampaio Moura, Maria Jose; Marcondes, Fernanda Klein (Elsevier B.V., 2013-05-30)
      Aims: This study was performed to assess isolated and combined effects of nandrolone and resistance training on the blood pressure, cardiac electrophysiology, and expression of the beta(1)- and beta(2)-adrenergic receptors ...

    • Lack of evidence for regulation of cardiac P-type ATPases and MAP kinases in transgenic mice with cardiac-specific overexpression of constitutively active α1B-adrenoceptors 

      Barreto, Frederico; Rezende, Daniele Campos; Scaramello, Christianne Bretas Vieira; Silva, Claudia Lucia Martins; Cunha, Valeria do Monti Nascimento; Caricati-Neto, Afonso [UNIFESP]; Jurkiewicz, Aron [UNIFESP]; Noël, Francois; Quintas, Luis Eduardo Menezes (Associação Brasileira de Divulgação Científica, 2010-05-01)
      The regulatory function of α1B-adrenoceptors in mammalian heart homeostasis is controversial. The objective of the present study was to characterize the expression/activity of key proteins implicated in cardiac calcium ...

    • Nandrolone and resistance training induce heart remodeling: Role of fetal genes and implications for cardiac pathophysiology 

      Tanno, Ana Paula; Neves, Vander José das; Rosa, Kaleizu Teodoro; Cunha, Tatiana Sousa [UNIFESP]; Linarello Giordano, Fernanda Cristina; Calil, Caroline Morini; Guzzoni, Vinicius; Fernandes, Tiago; Oliveira, Edilamar Menezes de; Novaes, Pedro Duarte; Irigoyen, Maria Claudia [UNIFESP]; Moura, Maria José Costa Sampaio; Marcondes, Fernanda Klein (Elsevier B.V., 2011-10-24)
      Aims: This study was conducted to assess the isolated and combined effects of nandrolone and resistance training on cardiac morphology, function, and mRNA expression of pathological cardiac hypertrophy markers.Main methods: ...

    • The renin-angiotensin system is modulated by swimming training depending on the age of spontaneously hypertensive rats 

      Zamo, Fernanda de Souza [UNIFESP]; Barauna, Valério Garrone; Chiavegatto, Silvana; Irigoyen, Maria Cláudia [UNIFESP]; Oliveira, Edilamar Menezes de (Elsevier B.V., 2011-07-18)
      Aim: To investigate the effects of swimming training on the renin-angiotensin system (RAS) during the development of hypertensive disease.Main methods: Male spontaneously hypertensive rats (SHR) were randomized into: ...

    • Unraveling the role of high-intensity resistance training on left ventricle proteome: Is there a shift towards maladaptation? 

      Dantas, Patricia Sousa [UNIFESP]; Sakata, Maisa Mayumi [UNIFESP]; Perez, Juliana Dineia [UNIFESP]; Watanabe, Regina Lucia Harumi [UNIFESP]; Bizerra, Fernando Cesar [UNIFESP]; Neves, Vander Jose das; Guzzoni, Vinicius; Marcondes, Fernanda Klein; Casarini, Dulce Elena [UNIFESP]; Cunha, Tatiana Sousa [UNIFESP] (Pergamon-Elsevier Science Ltd, 2016)
      High-intensity resistance training (RT) induces adaptations that improve physiological function. However, high intensity, volume and/or frequency may lead to injury and other health issues such as adverse cardiac effects. ...