Browsing by Subject "Cardiac hypertrophy"
Now showing items 1-6 of 6
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Dexamethasone-induced cardiac deterioration is associated with both calcium handling abnormalities and calcineurin signaling pathway activation
(Springer, 2017)Dexamethasone is a potent and widely used anti-inflammatory and immunosuppressive drug. However, recent evidences suggest that dexamethasone cause pathologic cardiac remodeling, which later impairs cardiac function. The ...
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Effects of nandrolone and resistance training on the blood pressure, cardiac electrophysiology, and expression of atrial beta-adrenergic receptors
(Elsevier B.V., 2013-05-30)Aims: This study was performed to assess isolated and combined effects of nandrolone and resistance training on the blood pressure, cardiac electrophysiology, and expression of the beta(1)- and beta(2)-adrenergic receptors ...
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Lack of evidence for regulation of cardiac P-type ATPases and MAP kinases in transgenic mice with cardiac-specific overexpression of constitutively active α1B-adrenoceptors
(Associação Brasileira de Divulgação Científica, 2010-05-01)The regulatory function of α1B-adrenoceptors in mammalian heart homeostasis is controversial. The objective of the present study was to characterize the expression/activity of key proteins implicated in cardiac calcium ...
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Nandrolone and resistance training induce heart remodeling: Role of fetal genes and implications for cardiac pathophysiology
(Elsevier B.V., 2011-10-24)Aims: This study was conducted to assess the isolated and combined effects of nandrolone and resistance training on cardiac morphology, function, and mRNA expression of pathological cardiac hypertrophy markers.Main methods: ...
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The renin-angiotensin system is modulated by swimming training depending on the age of spontaneously hypertensive rats
(Elsevier B.V., 2011-07-18)Aim: To investigate the effects of swimming training on the renin-angiotensin system (RAS) during the development of hypertensive disease.Main methods: Male spontaneously hypertensive rats (SHR) were randomized into: ...
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Unraveling the role of high-intensity resistance training on left ventricle proteome: Is there a shift towards maladaptation?
(Pergamon-Elsevier Science Ltd, 2016)High-intensity resistance training (RT) induces adaptations that improve physiological function. However, high intensity, volume and/or frequency may lead to injury and other health issues such as adverse cardiac effects. ...