Browsing by Subject "Calcium signaling"

Now showing items 1-6 of 6

    • Autophagy inhibited Ehrlich ascitic tumor cells apoptosis induced by the nitrostyrene derivative compounds: Relationship with cytosolic calcium mobilization 

      Calgarotto, Andrana Karla; Pereira, Gustavo José da Silva [UNIFESP]; Bechara, Alexandre [UNIFESP]; Paredes-Gamero, Edgar Julian [UNIFESP]; Barbosa, Christiano Marcello Vaz [UNIFESP]; Hirata, Hanako [UNIFESP]; Queiroz, Mary Luci de Souza; Smaili, Soraya Soubhi [UNIFESP]; Bincoletto, Claudia [UNIFESP] (Elsevier B.V., 2012-03-05)
      Apoptosis induction is often associated with increased autophagy, indicating interplay between these two important cellular events in cell death and survival. in this study, the programmed cell death and autophagy induced ...

    • Calmidazolium evokes high calcium fluctuations in Plasmodium falciparum 

      Budu, Alexandre [UNIFESP]; Gomes, Mayrim Machado [UNIFESP]; Melo, Pollyana Maria Saud [UNIFESP]; Maluf, Sarah El Chamy [UNIFESP]; Bagnaresi, Piero [UNIFESP]; Azevedo, Mauro Ferreira de; Carmona, Adriana Karaoglanovic [UNIFESP]; Gazarini, Marcos Leoni [UNIFESP] (Elsevier Science Inc, 2016)
      Calcium and calmodulin (CaM) are important players in eukaryote cell signaling. In the present study, by using a knockin approach, we demonstrated the expression and localization of CaM in all erythrocytic stages of ...

    • Effects of novel tacripyrines ITH12117 and ITH12118 on rat vas deferens contractions, calcium transients and cholinesterase activity 

      Pereira, Janaina Drawanz [UNIFESP]; Caricati-Neto, Afonso [UNIFESP]; Miranda-Ferreira, Regiane [UNIFESP]; Smaili, Soraya Soubhi [UNIFESP]; Godinho, Rosely Oliveira [UNIFESP]; los Rios, Cristobal de; Leon, Rafael; Villaroya, Mercedes; Samadi, Abdelouahid; Marco-Contelles, Jose; Jurkiewicz, Neide Hyppolito [UNIFESP]; Garcia, Antonio G.; Jurkiewicz, Aron [UNIFESP] (Elsevier B.V., 2011-06-25)
      We have recently synthesized a new series of hybrid compounds having the moieties of tacrine, a potent inhibitor of brain and peripheral acetylcholinesterase (AChE), and nimodipine, a blocker of L-type voltage-dependent ...

    • Functional and molecular evidence for heteromeric association of P2Y(1) receptor with P2Y(2) and P2Y(4) receptors in mouse granulocytes 

      Ribeiro-Filho, Antonio Carlos; Buri, Marcus Vinicius [UNIFESP]; Barros, Carlos Castilho; Dreyfuss, Juliana Luporini [UNIFESP]; Nader, Helena Bonciani [UNIFESP]; Justo, Giselle Zenker [UNIFESP]; Craveiro, Rogerio Bastos [UNIFESP]; Pesquero, Joao Bosco [UNIFESP]; Miranda, Antonio [UNIFESP]; Ferreira, Alice Teixeira [UNIFESP]; Paredes-Gamero, Edgar Julian [UNIFESP] (Biomed Central Ltd, 2016)
      Background: All hematopoietic cells express P2 receptors, however pharmacological characteristics such as expression and affinity in granulocytes are unknown. Methods: Pharmacological characteristics of P2 receptors were ...

    • Secreção de insulina, sinalização de Ca2+ e função mitocondrial em ilhotas de ratas senescentes 

      Coelho, Fernanda Monteiro [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2010-08-25)
      Aging is associated with changes in pancreatic β cells sensitivity to nutrients resulting in glucose intolerance and diabetes mellitus (DM) type 2 (DM 2) development. Here the study cells function Ca2+ signaling, mitochondrial ...

    • Specific calpain activity evaluation in Plasmodium parasites 

      Gomes, Mayrim Machado [UNIFESP]; Budu, Alexandre [UNIFESP]; Ventura, Priscilla Dantas de Souza [UNIFESP]; Bagnaresi, Piero [UNIFESP]; Cotrin, Simone Silva [UNIFESP]; Cunha, Rodrigo Luiz Oliveira Rodrigues; Carmona, Adriana Karaoglanovic [UNIFESP]; Juliano, Luiz [UNIFESP]; Gazarini, Marcos Leoni [UNIFESP] (Elsevier B.V., 2015-01-01)
      In the intraerythrocytic trophozoite stages of Plasmodium falciparum, the calcium-dependent cysteine protease calpain (Pf-calpain) has an important role in the parasite calcium modulation and cell development. We established ...