Now showing items 1-10 of 46

    • Abnormalities in Metalloproteinase Pathways and IGF-I Axis: A Link Between Birth Weight, Hypertension, and Vascular Damage in Childhood 

      Sesso, Ricardo de Castro Cintra [UNIFESP]; Franco, Maria do Carmo Pinho [UNIFESP] (Nature Publishing Group, 2010-01-01)
      BACKGROUNDAlthough numerous studies suggest an inverse relationship between birth weight and cardiovascular disease, the mechanistic basis of this phenomenon is not fully understood. Here, we postulate that alterations in ...

    • ACE activity is modulated by the enzyme alpha-galactosidase A 

      Batista, Elice Carneiro; Carvalho, Luiz Roberto; Casarini, Dulce Elena [UNIFESP]; Carmona, Adriana Karaoglanovic; Santos, Edson Lucas dos; Silva, Elton Dias da; Santos, Robson Augusto dos; Nakaie, Clovis Ryuichi; Munoz Rojas, Maria Veronica; Oliveira, Suzana Macedo de; Bader, Michael; D'Almeida, Vania [UNIFESP]; Martins, Ana Maria [UNIFESP]; Souza, Kely de Picoly; Pesquero, Joao Bosco [UNIFESP] (Springer, 2011-01-01)
      Fabry disease is a multisystem X-linked disorder resulting from alpha-galactosidase A (alpha-GalA) gene mutations leading to the accumulation of globotriaosylceramide mainly in endothelium compromising heart, kidney, and ...

    • Albuminuria, renal function and blood pressure in undernourished children and recovered from undernutrition 

      Martins, Vinicius J. B.; Sesso, Ricardo [UNIFESP]; Clemente, Ana P. G.; Fernandes, Mariana B. F. [UNIFESP]; Sawaya, Ana L. [UNIFESP] (Springer, 2017)
      Background The objective of this study was to investigate some biomarkers of renal function and blood pressure in children who had recovered from undernutrition. Methods This was cross-sectional, comparative study in which ...

    • Association of ACE Gene Insertion/Deletion Polymorphism With Birth Weight, Blood Pressure Levels, and ACE Activity in Healthy Children 

      Ajala, Aline Rodrigues [UNIFESP]; Almeida, Sandro Soares [UNIFESP]; Rangel, Marina [UNIFESP]; Palomino, Zaira [UNIFESP]; Strufaldi, Maria Wany Louzada [UNIFESP]; Puccini, Rosana Fiorini [UNIFESP]; Araújo, Ronaldo de Carvalho [UNIFESP]; Casarini, Dulce Elena [UNIFESP]; Franco, Maria do Carmo Pinho [UNIFESP] (Nature Publishing Group, 2012-07-01)
      BACKGROUNDThe human angiotensin-converting enzyme (ACE) gene contains a polymorphism consisting of either an insertion (I) or a deletion (D) of a 287 bp Alu repetitive sequence in intron 16. the potential role of ACE ...

    • Association of adipokines with cardiovascular risk factors in low birth weight children: a case-control study 

      Strufaldi, Maria Wany Louzada [UNIFESP]; Puccini, Rosana Fiorini [UNIFESP]; Silverio, Olga Maria Amancio [UNIFESP]; Franco, Maria Carmo do Pinho [UNIFESP] (Springer, 2013-01-01)
      Our aim was to investigate plasma levels of adiponectin, monocyte chemoattractant protein-1 (MCP-1) and plasminogen activator inhibitor-1 (PAI-1) in low birth weight (LBW) children and to determine correlations among these ...

    • Autonomic changes in young smokers: acute effects of inspiratory exercise 

      Rodrigues, Fernando; Araujo, Amanda Aparecida; Mostarda, Cristiano Teixeira; Ferreira, Janaina; Barros Silva, Michelle Cristina de; Nascimento, Ademir Manoel; Lira, Fabio Santos [UNIFESP]; De Angelis, Katia; Irigoyen, Maria Claudia; Rodrigues, Bruno (Springer, 2013-08-01)
      One of the most important consequences of smoking is the development of cardiovascular diseases. However, little is known about the early consequences of smoking and the acute effects of a single inspiratory muscle exercise ...

    • A baixa estatura leve está associada ao aumento da pressão arterial em adolescentes com sobrepeso 

      Clemente, Ana Paula Grotti [UNIFESP]; Santos, Carla Danusa [UNIFESP]; Benedito-Silva, Ana Amélia [UNIFESP]; Martins, Vinícius José Baccin [UNIFESP]; Marchesano, Anna Carolina [UNIFESP]; Fernandes, Mariana Belluca [UNIFESP]; Albuquerque, Maria Paula; Sawaya, Ana Lydia [UNIFESP] (Sociedade Brasileira de Cardiologia - SBC, 2012-01-01)
      BACKGROUND: Studies have shown that pre/postnatal undernutrition leads to higher risk of non communicable diseases such as diabetes, hypertension and obesity in adulthood. OBJECTIVE: To determine whether overweight adolescents ...

    • Baroreflex function in conscious rats submitted to iron overload 

      Cardoso, Leonardo Máximo; Pedrosa, Maria Lúcia Silva; Silva, Marcelo Eustáquio; Moraes, Márcio Flávio Dutra; Colombari, Eduardo [UNIFESP]; Chianca-Junior, Deoclécio Alves (Associação Brasileira de Divulgação Científica, 2005-02-01)
      Our hypothesis is that iron accumulated in tissue, rather than in serum, may compromise cardiovascular control. Male Fischer 344 rats weighing 180 to 220 g were divided into 2 groups. In the serum iron overload group (SIO, ...

    • Blood pressure levels in childhood: probing the relative importance of birth weight and current size 

      Strufaldi, Maria Wany Louzada [UNIFESP]; Silva, Edina Mariko Koga da [UNIFESP]; Franco, Maria do Carmo Pinho [UNIFESP]; Puccini, Rosana Fiorini [UNIFESP] (Springer, 2009-05-01)
      Several studies have reported data supporting the idea that an impaired intrauterine environment that deprives the fetus of optimal nutrient delivery results in the predisposition of the fetus to experience cardiovascular ...

    • Cardiorespiratory response to exercise in men and women with obstructive sleep apnea 

      Cintra, Fatima [UNIFESP]; Poyares, Dalva [UNIFESP]; Rizzi, Camila F. [UNIFESP]; Risso, Thais T. [UNIFESP]; Skomro, Robert [UNIFESP]; Montuori, Emilio [UNIFESP]; Mello-Fujita, Luciane [UNIFESP]; Paola, Angelo de [UNIFESP]; Tufik, Sergio [UNIFESP] (Elsevier B.V., 2009-03-01)
      Background OSA severity has been associated with self-reported lack of exercise. Most of the research has been done with men recruited from sleep clinics. There is limited data on the exercise performance of women with ...