Now showing items 1-10 of 49

    • Abnormal brain oscillations persist after recovery from bipolar depression 

      Canali, P.; Casarotto, S.; Rosanova, M.; Sferrazza-Papa, G.; Casali, A. G. [UNIFESP]; Gosseries, O.; Massimini, M.; Smeraldi, E.; Colombo, C.; Benedetti, F. (Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)
      When directly perturbed in healthy subjects, premotor cortical areas generate electrical oscillations in the beta range (20-40 Hz). In schizophrenia, major depressive disorder and bipolar disorder (BD), these oscillations ...

    • Adipokines, metabolic dysfunction and illness course in bipolar disorder 

      Mansur, Rodrigo B. [UNIFESP]; Rizzo, Lucas B. [UNIFESP]; Santos, Camila M. [UNIFESP]; Asevedo, Elson [UNIFESP]; Cunha, Graccielle R. [UNIFESP]; Noto, Mariane N. [UNIFESP]; Pedrini, Mariana [UNIFESP]; Zeni, Maiara [UNIFESP]; Cordeiro, Quirino; McIntyre, Roger S.; Brietzke, Elisa [UNIFESP] (Pergamon-Elsevier Science Ltd, 2016)
      Replicated evidence indicates that individuals with BD are differentially affected by metabolic comorbidities and that its occurrence is a critical mediator and/or moderator of BD outcomes. This study aimed to explore the ...

    • The Affective and Emotional Composite Temperament (AFECT) model and scale: A system-based integrative approach 

      Lara, Diogo R.; Bisol, Luisa W.; Brunstein, Miriam G.; Reppold, Caroline T.; Carvalho, Hudson W. de [UNIFESP]; Ottoni, Gustavo L. (Elsevier B.V., 2012-09-01)
      Based on many temperament frameworks, here we propose an integration of emotional and affective temperaments (the AFECT model), forming a common substrate for mood, behavior, personality and part of cognition. Temperament ...

    • As bases neurobiológicas do transtorno bipolar 

      Machado-Vieira, Rodrigo; Bressan, Rodrigo Affonseca [UNIFESP]; Frey, Benício; Soares, Jair C. (Faculdade de Medicina da Universidade de São Paulo, 2005-01-01)
      In this article, the authors review relevant aspects related to the neurobiological basis of bipolar disorder. This illness has been associated with complex biochemical and molecular changes in brain circuits linked to ...

    • Challenges and developments in research of the early stages of bipolar disorder 

      Brietzke, Elisa [UNIFESP]; Rosa, Adriane R.; Pedrini, Mariana [UNIFESP]; Noto, Mariane Nunes [UNIFESP]; Kapczinski, Flavio; Scott, Jan (Assoc Brasileira Psiquiatria, 2016)
      Recently, attention in the field of bipolar disorder (BD) has focused on prevention, including early detection and intervention, as these strategies have the potential to delay, lessen the severity, or even prevent full-blown ...

    • Circadian preference in bipolar disorder 

      Falsin Giglio, Larriany Maria; Magalhaes, Pedro V. S.; Andersen, Monica Levy [UNIFESP]; Walz, Julio Cesar; Jakobson, Lourenco; Kapczinski, Flavio (Springer, 2010-06-01)
      A role for circadian rhythm abnormalities in the pathogenesis of bipolar disorder (BD) has been suggested. the present study assessed circadian preference, a subjective preference for activities in the morning or evening ...

    • The contextual fear conditioning deficit presented by spontaneously hypertensive rats (SHR) is not improved by mood stabilizers 

      Calzavara, Mariana Bendlin [UNIFESP]; Medrano, Wladimir Agostini [UNIFESP]; Levin, Raquel [UNIFESP]; Libanio, Tania Cristina [UNIFESP]; Ribeiro, Rosana de Alencar [UNIFESP]; Abilio, Vanessa Costhek [UNIFESP] (Elsevier B.V., 2011-08-15)
      Objectives: We have recently reported that spontaneously hypertensive rats (SHR) present a contextual fear conditioning (CFC) deficit. This deficit is improved by antipsychotic drugs, potentiated by proschizophrenia ...

    • Cytokine Alterations in Bipolar Disorder: A Meta-Analysis of 30 Studies 

      Modabbernia, Amirhossein; Taslimi, Shervin; Brietzke, Elisa [UNIFESP]; Ashrafi, Mandana (Elsevier B.V., 2013-07-01)
      Background: We conducted a meta-analysis of studies comparing cytokine concentrations between patients with bipolar disorder (BD) and healthy control subjects (HCs).Methods: We searched ISI Web of Science, MEDLINE, BIOSIS ...

    • Desfechos propostos em protocolos de estudos clínicos que avaliam opções de tratamento farmacológico da mania 

      Silva, Raquel Lustosa da [UNIFESP] (Universidade Federal de São Paulo, 2022-12-19)
      Introdução: Um processo importante do planejamento dos protocolos de estudos clínicos é a seleção dos desfechos, pois é por meio deles que se avaliam o quanto os tratamentos podem ou não contribuir para a melhora ou cura ...

    • Desfechos propostos para avaliação da depressão bipolar: uma revisão de escopo de protocolos de estudos clínicos 

      Santos, Gabriela Melanias dos [UNIFESP] (Universidade Federal de São Paulo, 2022-07-29)
      Introdução: A seleção dos desfechos que avaliarão o quanto os tratamentos podem ou não contribuir para a melhora ou cura dos pacientes é uma parte importante do planejamento dos estudos clínicos. Atualmente, o clinicaltrials.gov ...