Now showing items 1-10 of 130

    • Acute treatment with alcohol affects calcium signaling and contraction associated with apoptosis in vas deferens of periadolescent rats 

      Verde, Luciana Ferreira [UNIFESP]; Lopes, Guiomar Silva [UNIFESP]; Miki Ihara, Silvia Saiuli [UNIFESP]; Jurkiewicz, Neide Hyppolito [UNIFESP]; Jurkiewicz, Aron [UNIFESP] (Elsevier B.V., 2014-07-15)
      Our purpose was to verify if alcohol causes alterations on translocation of Ca2+ and tension induced by KCl or noradrenaline in vas deferens of periadolescent Wistar rats. A single dose of alcohol (i.p. 3.0 g/kg) or saline ...

    • Aerobic exercise training and low-level laser therapy modulate inflammatory response and degenerative process in an experimental model of knee osteoarthritis in rats 

      Assis, Livia [UNIFESP]; Milares, Luiz Paulo [UNIFESP]; Almeida, Thais [UNIFESP]; Tim, Carla; Magri, Angela Maria Paiva [UNIFESP]; Fernandes, Kelly Rossetti [UNIFESP]; Medalha, Carla Christina [UNIFESP]; Renno, Ana Claudia Muniz [UNIFESP] (Elsevier Sci Ltd, 2016)
      Objective: The aim of this study was to evaluate the effects of an aerobic exercise training and low-level laser therapy (LLLT) (associated or not) on degenerative modifications and inflammatory mediators on the articular ...

    • alpha-Pinene isolated from Schinus terebintinfolius Raddi (Anacardiaceae) induces apoptosis and confers antimetastatic protection in a melanoma model 

      Matsuo, Alisson Leonardo [UNIFESP]; Figueiredo, Carlos Rogerio [UNIFESP]; Arruda, Denise Costa [UNIFESP]; Pereira, Felipe Valença [UNIFESP]; Scutti, Jorge Augusto Borin [UNIFESP]; Massaoka, Mariana Hiromi [UNIFESP]; Travassos, Luiz Rodolpho [UNIFESP]; Sartorelli, Patricia [UNIFESP]; Lago, Joao Henrique Ghilardi [UNIFESP] (Elsevier B.V., 2011-07-29)
      Malignant melanoma is one the most aggressive types of cancer and its incidence has gradually increased in the last years, accounting for about 75% of skin cancer deaths. This poor prognosis results from the tumor resistance ...

    • Alterações degenerativas induzidas pela privação de sono paradoxal em glândula sublingual de ratos 

      Aguiar, Gabriel Carvalhal de [UNIFESP] (Universidade Federal de São Paulo, 26-04-23)
      O ser humano passa cerca de um terço de sua vida dormindo, processo este fundamental para a manutenção e equilíbrio dos mecanismos psicossocial e biológico. O sono é um processo natural e complexo, e a falta dele pode ...

    • Alterations in Calcium Signaling and a Decrease in Bcl-2 Expression: Possible Correlation With Apoptosis in Aged Striatum 

      Ureshino, Rodrigo Portes [UNIFESP]; Bertoncini, Clelia Rejane Antonio [UNIFESP]; Fernandes, Maria Jose da Silva [UNIFESP]; Abdalla, Fernando Mauricio Francis; Porto, Catarina Segreti [UNIFESP]; Hsu, Yi-Te; Lopes, Guiomar Silva [UNIFESP]; Smaili, Soraya Soubhi [UNIFESP] (Wiley-Blackwell, 2010-02-01)
      Aging is a multifaceted process associated with various functional and structural deficits that might be evolved in degenerative diseases. It has been shown that neurodegenerative disorders are associated with alterations ...

    • Alterations in the proliferative/apoptotic equilibrium in semen of adolescents with varicocele 

      Belardin, Larissa Berloffa [UNIFESP]; Del Giudice, Paula Toni [UNIFESP]; Camargo, Mariana [UNIFESP]; Intasqui, Paula [UNIFESP]; Antoniassi, Mariana Pereira [UNIFESP]; Bertolla, Ricardo Pimenta [UNIFESP]; Cedenho, Agnaldo Pereira [UNIFESP] (Springer/Plenum Publishers, 2016)
      To verify if the presence of varicocele (grades II and III) with and without seminal alterations, using the 5(th) centile cutoff values in table A1.1 of the World Health Organization (WHO, 2010) manual, alters the seminal ...

    • Altered of apoptotic markers of both extrinsic and intrinsic pathways induced by hepatitis C virus infection in peripheral blood mononuclear cells 

      Albertoni, Guilherme [UNIFESP]; Arnoni, Carine Prisco; Latini, Flavia Roche Moreira; Andrade, Sheila Siqueira [UNIFESP]; Araujo, Patricia Regina Barboza; Rodrigues, Flaviane Kesia; Rozenchan, Patricia Bortman [UNIFESP]; Mendes-Correa, Maria Cassia; Leite, Olavo Henrique Munhoz; Schor, Nestor [UNIFESP]; Girão, Manoel João Batista Castello [UNIFESP]; Barreto, Jose Augusto (Biomed Central Ltd, 2012-12-20)
      Background: Chronic hepatitis C (CHC) has emerged as a leading cause of cirrhosis in the U. S. and across the world. To understand the role of apoptotic pathways in hepatitis C virus (HCV) infection, we studied the mRNA ...

    • Análise do estresse oxidativo e da apoptose no ovário de ratas tratadas com isoflavonas da soja 

      Teixeira, Cristiane de Paula [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2018-05-24)
      Ovarian aging is characterized by declines in follicular reserve and diminished oocyte quality that culminates in menopause, responsible for several disorders and chronic diseases. Oxidative stress seems to modulate ...

    • The antineoplastic busulphan impairs peritubular and Leydig cells, and vitamin B-12 stimulates spermatogonia proliferation and prevents busulphan-induced germ cell death 

      Sasso-Cerri, Estela; Oliveira, Barbara; de Santi, Fabiane [UNIFESP]; Beltrame, Flavia L. [UNIFESP]; Caneguim, Breno H. [UNIFESP]; Cerri, Paulo S. (Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)
      Busulphan (Bu), an alkylating agent used for bone marrow and spermatogonial stem cell transplantation (SSCT), impairs Sertoli (SC) cells, which are necessary for the spermatogonial stem cell (SSC) homing during transplantation. ...

    • Antioxidant dietary deficiency induces caspase activation in chick skeletal muscle cells 

      Nunes, Viviane A. [UNIFESP]; Gozzo, Andrezza Justino [UNIFESP]; Juliano, Maria Aparecida [UNIFESP]; Cerqueira César, M.; Sampaio, Misako Uemura [UNIFESP]; Sampaio, Claudio a.m. [UNIFESP]; Araujo, Mariana da Silva [UNIFESP] (Associação Brasileira de Divulgação Científica, 2003-08-01)
      Apoptosis and necrosis are two distinct forms of cell death that can occur in response to different agents and stress conditions. In order to verify if the oxidative stress induced by dietary selenium and vitamin E ...