Now showing items 1-10 of 124

    • Acute treatment with alcohol affects calcium signaling and contraction associated with apoptosis in vas deferens of periadolescent rats 

      Verde, Luciana Ferreira [UNIFESP]; Lopes, Guiomar Silva [UNIFESP]; Miki Ihara, Silvia Saiuli [UNIFESP]; Jurkiewicz, Neide Hyppolito [UNIFESP]; Jurkiewicz, Aron [UNIFESP] (Elsevier B.V., 2014-07-15)
      Our purpose was to verify if alcohol causes alterations on translocation of Ca2+ and tension induced by KCl or noradrenaline in vas deferens of periadolescent Wistar rats. A single dose of alcohol (i.p. 3.0 g/kg) or saline ...

    • Aerobic exercise training and low-level laser therapy modulate inflammatory response and degenerative process in an experimental model of knee osteoarthritis in rats 

      Assis, Livia [UNIFESP]; Milares, Luiz Paulo [UNIFESP]; Almeida, Thais [UNIFESP]; Tim, Carla; Magri, Angela Maria Paiva [UNIFESP]; Fernandes, Kelly Rossetti [UNIFESP]; Medalha, Carla Christina [UNIFESP]; Renno, Ana Claudia Muniz [UNIFESP] (Elsevier Sci Ltd, 2016)
      Objective: The aim of this study was to evaluate the effects of an aerobic exercise training and low-level laser therapy (LLLT) (associated or not) on degenerative modifications and inflammatory mediators on the articular ...

    • alpha-Pinene isolated from Schinus terebintinfolius Raddi (Anacardiaceae) induces apoptosis and confers antimetastatic protection in a melanoma model 

      Matsuo, Alisson Leonardo [UNIFESP]; Figueiredo, Carlos Rogerio [UNIFESP]; Arruda, Denise Costa [UNIFESP]; Pereira, Felipe Valença [UNIFESP]; Scutti, Jorge Augusto Borin [UNIFESP]; Massaoka, Mariana Hiromi [UNIFESP]; Travassos, Luiz Rodolpho [UNIFESP]; Sartorelli, Patricia [UNIFESP]; Lago, Joao Henrique Ghilardi [UNIFESP] (Elsevier B.V., 2011-07-29)
      Malignant melanoma is one the most aggressive types of cancer and its incidence has gradually increased in the last years, accounting for about 75% of skin cancer deaths. This poor prognosis results from the tumor resistance ...

    • Alterations in the proliferative/apoptotic equilibrium in semen of adolescents with varicocele 

      Belardin, Larissa Berloffa [UNIFESP]; Del Giudice, Paula Toni [UNIFESP]; Camargo, Mariana [UNIFESP]; Intasqui, Paula [UNIFESP]; Antoniassi, Mariana Pereira [UNIFESP]; Bertolla, Ricardo Pimenta [UNIFESP]; Cedenho, Agnaldo Pereira [UNIFESP] (Springer/Plenum Publishers, 2016)
      To verify if the presence of varicocele (grades II and III) with and without seminal alterations, using the 5(th) centile cutoff values in table A1.1 of the World Health Organization (WHO, 2010) manual, alters the seminal ...

    • Altered of apoptotic markers of both extrinsic and intrinsic pathways induced by hepatitis C virus infection in peripheral blood mononuclear cells 

      Albertoni, Guilherme [UNIFESP]; Arnoni, Carine Prisco; Latini, Flavia Roche Moreira; Andrade, Sheila Siqueira [UNIFESP]; Araujo, Patricia Regina Barboza; Rodrigues, Flaviane Kesia; Rozenchan, Patricia Bortman [UNIFESP]; Mendes-Correa, Maria Cassia; Leite, Olavo Henrique Munhoz; Schor, Nestor [UNIFESP]; Girão, Manoel João Batista Castello [UNIFESP]; Barreto, Jose Augusto (Biomed Central Ltd, 2012-12-20)
      Background: Chronic hepatitis C (CHC) has emerged as a leading cause of cirrhosis in the U. S. and across the world. To understand the role of apoptotic pathways in hepatitis C virus (HCV) infection, we studied the mRNA ...

    • The antineoplastic busulphan impairs peritubular and Leydig cells, and vitamin B-12 stimulates spermatogonia proliferation and prevents busulphan-induced germ cell death 

      Sasso-Cerri, Estela; Oliveira, Barbara; de Santi, Fabiane [UNIFESP]; Beltrame, Flavia L. [UNIFESP]; Caneguim, Breno H. [UNIFESP]; Cerri, Paulo S. (Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)
      Busulphan (Bu), an alkylating agent used for bone marrow and spermatogonial stem cell transplantation (SSCT), impairs Sertoli (SC) cells, which are necessary for the spermatogonial stem cell (SSC) homing during transplantation. ...

    • Antioxidant dietary deficiency induces caspase activation in chick skeletal muscle cells 

      Nunes, Viviane A. [UNIFESP]; Gozzo, Andrezza Justino [UNIFESP]; Juliano, Maria Aparecida [UNIFESP]; Cerqueira César, M.; Sampaio, Misako Uemura [UNIFESP]; Sampaio, Claudio a.m. [UNIFESP]; Araujo, Mariana da Silva [UNIFESP] (Associação Brasileira de Divulgação Científica, 2003-08-01)
      Apoptosis and necrosis are two distinct forms of cell death that can occur in response to different agents and stress conditions. In order to verify if the oxidative stress induced by dietary selenium and vitamin E ...

    • Antioxidant supplementation decreases the cell death rate in the prostatic stromal tissue of long-term castrated rats 

      Fartes, Guilherme [UNIFESP]; Lorenzetti, Fábio [UNIFESP]; Salvador, Larissa Beloti [UNIFESP]; Ortiz, Valdemar [UNIFESP]; Dambros, Miriam [UNIFESP] (Sociedade Brasileira de Urologia, 2012-06-01)
      OBJECTIVE: The purpose of this study was to compare the effects of castration on cell death rate of the adult rat prostates and to evaluate the benefic action of alpha tocopherol supplementation to avoid apoptosis ...

    • Antiproliferative in vitro effects of BI 2536-mediated PLK1 inhibition on cervical adenocarcinoma cells 

      Pezuk, Julia A.; Brassesco, Maria Sol; Oliveira, Jaqueline C.; Morales, Andressa G.; Montaldi, Ana P.; Sakamoto-Hojo, Elza T.; Scrideli, Carlos A.; Tone, Luiz G. (Springer, 2013-02-01)
      Cervical adenocarcinoma is one of the most common gynecological malignancies. Despite the improvements in multimodality treatment, advanced disease is still associated with a significantly poor prognosis making the search ...

    • Apoptose e alterações testiculares em ratos albinos tratados com etoposide na fase pré-púbere 

      Stumpp, Taiza [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2002)
      O etoposide e um derivado semi-sintetico da podofilotoxina, muito utilizado em varios tipos de tratamento quimioterapico, incluindo a oncologia pediatrica. Pesquisas anteriores propuseram que a atividade antimitotica do ...