Browsing by Subject "Antitumoral"
Now showing items 1-7 of 7
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Avaliação da segurança e eficácia "in vitro" da Cuscuta racemosa Martius
(Universidade Federal de São Paulo, 2017-07-04)Cuscuta racemosa, Mart is a parasitic plant belonging to the family Convolvulaceae, known in Brazil for the popular synonymy of "cipó chumbo" and "yarn of eggs". It is popularly used for its anti-inflammatory and healing ...
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Caracterização farmacológica da Crotamina sintética como antitumoral em modelos de melanoma in vivo. Otimização da atividade neoplásica com uso de adjuvantes
(Universidade Federal de São Paulo (UNIFESP), 2020-05-28)Toxins are of great scientific interest, mainly due to their possible use for therapeutic purposes as drugs, or as a structural model for its development. Crotamine, which is one of the most abundant toxins present in the ...
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Cytotoxic effects of dillapiole on MDA-MB-231 cells involve the induction of apoptosis through the mitochondrial pathway by inducing an oxidative stress while altering the cytoskeleton network
(Elsevier B.V., 2014-04-01)Breast cancer is the world's leading cause of death among women. This situation imposes an urgent development of more selective and less toxic agents. the use of natural molecular fingerprints as sources for new bioactive ...
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Funcionalização De Nanopartículas Metálicas Com Diferentes Combinações De Peptídeos Para Aplicações Como Agentes Antimicrobianos E Antitumorais
(Universidade Federal de São Paulo (UNIFESP), 2017-11-27)Metal nanoparticles (NPs) have showing promising applications in the biomedical field. These NPs have unique physicochemical properties, as well as great chemical versatility on their surface, which allows new modifications ...
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Growth inhibition and pro-apoptotic activity of violacein in Ehrlich ascites tumor
(Elsevier B.V., 2010-06-07)The continuing threat to biodiversity lends urgency to the need of identification of sustainable source of natural products. This is not so much trouble if there is a microbial source of the compound. Herein, violacein, a ...
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Modulação do eixo PLCγ1, Ca2+/CAMKII e PKC em células de leucemia mieloide crônica tratadas com violaceína
(Universidade Federal de São Paulo (UNIFESP), 2020-07-30)Violacein is an indole derivative isolated from Chromobacterium violaceum with potential antitumor activity and specific mechanisms of action in vitro and in vivo. This compound was evaluated in vitro in cultures of chronic ...
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Reações de bromoaminociclização enantiosseletivas visando a síntese de bases esfingóides
(Universidade Federal de São Paulo, 2022-03-04)A porção aminoálcool é um constituinte estrutural presente em diversas moléculas, sejam elas de ocorrência natural ou não, que apresentam diversas atividades biológicas relevantes. Dentre elas, existem os aminoálcoois de ...
