Browsing by Subject "Antitumor"
Now showing items 1-9 of 9
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Action and function of Chromobacterium violaceum in health and disease: Violacein as a promising metabolite to counteract gastroenterological diseases
(Elsevier Sci Ltd, 2017)Chromobacterium violaceum is a Gram negative, beta-proteobacterium found in the microbiota of tropical and subtropical environments. Although considered an opportunistic pathogen, infection rapidly progress to fatal sepsis, ...
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Avaliação da segurança e eficácia "in vitro" da Cuscuta racemosa Martius
(Universidade Federal de São Paulo, 2017-07-04)Cuscuta racemosa, Mart is a parasitic plant belonging to the family Convolvulaceae, known in Brazil for the popular synonymy of "cipó chumbo" and "yarn of eggs". It is popularly used for its anti-inflammatory and healing ...
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First-time Isolation of Flavonoids and Cytotoxic Potential of the Amazonian Shrub Ptychopetalum olacoides Benth
(Brazilian Chemical Soc, 2017)In the present study, three flavonoids, 3-O-methylquercetin (1), 3,4'-O-dimethylquercetin (2) and 3,7-O-dimethylquercetin (3) were isolated and characterized for the first time from a methanol extract obtained from the ...
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Funcionalização De Nanopartículas Metálicas Com Diferentes Combinações De Peptídeos Para Aplicações Como Agentes Antimicrobianos E Antitumorais
(Universidade Federal de São Paulo (UNIFESP), 2017-11-27)Metal nanoparticles (NPs) have showing promising applications in the biomedical field. These NPs have unique physicochemical properties, as well as great chemical versatility on their surface, which allows new modifications ...
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Growth inhibitory activity of a novel lectin from Cliona varians against K562 human erythroleukemia cells
(Springer, 2009-05-01)Purpose in this study, the antitumoral potential of a novel lectin (CvL) purified from the marine sponge Cliona varians was studied in different cancer cell lines.Methods CvL cytotoxicity was evaluated in mammalian tumor ...
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In vivo effects of the association of the psychoactive phenotiazine thioridazine on antitumor activity and hind limb paralysis induced by the native polypeptide crotamine
(Elsevier, 2020-10-15)Crotamine is a cationic polypeptide composed by 42 amino acid residues with several pharmacological and biological properties, including the selective ability to enter and kill actively proliferating tumour cells, which ...
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A Kunitz-type FXa inhibitor affects tumor progression, hypercoagulable state and triggers apoptosis
(Elsevier B.V., 2013-04-01)Cancer is linked to hypercoagulability, and many studies have shown that anticoagulant drugs affect tumor progression. in this study was demonstrated that the Amblyomin-X (which is a recombinant protein that exerts similarity ...
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Nanocarreadores de fármacos anti-inflamatórios não esteroidais (AINEs) e antitumorais: uma revisão comparativa entre suas variações e vantagens da sua utilização
(Universidade Federal de São Paulo, 2022-06-24)Nanomaterias estão sendo cada vez mais utilizados para transporte de fármacos afim de auxiliar na terapia de diversas doenças. Isto porquê os carreadores vem apresentando muitas vantagens nos estudos ao longo dos últimos ...
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Safe therapeutics of murine melanoma model using a novel antineoplasic, the partially methylated mannogalactan from Pleurotus eryngii
(Elsevier Sci Ltd, 2017)A heteropolysaccharide was isolated by cold aqueous extraction from edible mushroom Pleurotus eryngii ("King Oyster") basidiocarps and its biological properties were evaluated. Structural assignments were carried out using ...
