Browsing by Subject "Antipsychotic"
Now showing items 1-6 of 6
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Adjunctive Treatment with Lodenafil Carbonate for Erectile Dysfunction in Outpatients with Schizophrenia and Spectrum: A Randomized, Double-Blind, Crossover, Placebo-Controlled Trial
(Wiley-Blackwell, 2013-04-01)Introduction. Evidence is accumulating to support the presence of erectile dysfunction in patients with schizophrenia. This dysregulation may be amenable to therapeutic intervention to improve adherence and quality of life ...
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Avaliação dos possíveis efeitos terapêuticos e preventivos da N-acetilcisteína em comportamentos associados com os sintomas positivos e negativos da esquizofrenia em animais da linhagem SHR
(Universidade Federal de São Paulo (UNIFESP), 2019-12-18)Schizophrenia is a neurodevelopmental disorder that involves genetic and environmental factors, but its pathophysiology is not fully defined. Oxidative stress is a common point among the main hypotheses that seek to elucidate ...
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Effect of antipsychotic drugs on gene expression in the prefrontal cortex and nucleus accumbens in the spontaneously hypertensive rat (SHR)
(Elsevier B.V., 2014-08-01)Antipsychotic drugs (APDs) are the standard treatment for schizophrenia. the therapeutic effect of these drugs is dependent upon the dopaminergic D2 blockade, but they also modulate other neurotransmitter pathways. the ...
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Effects of psychostimulants and antipsychotics on serum lipids in an animal model for schizophrenia
(MDPI AG, 2021-02-26)Schizophrenia (SCZ) treatment is essentially limited to the use of typical or atypical antipsychotic drugs, which suppress the main symptoms of this mental disorder. Metabolic syndrome is often reported in patients with ...
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Implications of epigenetic modulation for novel treatment approaches in patients with schizophrenia
(Elsevier B.V., 2014-02-01)Schizophrenia is a heterogeneous and complex mental disorder with high rates of disability, non-recovery, and relapse. the primary pharmacological treatments for schizophrenia are antipsychotics. Notwithstanding the efficacy ...
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Regulation of monoamine levels by typical and atypical antipsychotics in Caenorhabditis elegans mutant for nuclear distribution element genes
(Elsevier, 2021-07)Mammalian nuclear distribution genes encode proteins with essential roles in neuronal migration and brain formation during embryogenesis. The implication of human nuclear distribution genes, namely nudC and NDE1 (Nuclear ...
