Now showing items 1-7 of 7

    • Expression and functional characterization of boophilin, a thrombin inhibitor from Rhipicephalus (Boophilus) microplus midgut 

      Soares, Tatiane Sanches [UNIFESP]; Watanabe, Renata Midori Okuta [UNIFESP]; Tanaka-Azevedo, Anita Mitico; Torquato, Ricardo Jose Soares [UNIFESP]; Lu, Stephen [UNIFESP]; Figueiredo, Ana Carvalho; Pereira, Pedro Jose Barbosa; Tanaka, Aparecida Sadae [UNIFESP] (Elsevier B.V., 2012-07-06)
      Rhipicephalus (Boophilus)microplus is an ectoparasite responsible for an important decrease in meat, milk and leather production, caused both by cattle blood loss and by the transmission of anaplasmosis and babesiosis. R. ...

    • Immobilized Cratylia mollis lectin: An affinity matrix to purify a soybean (Glycine max) seed protein with in vitro platelet antiaggregation and anticoagulant activities 

      Silva, Mariana C. C. [UNIFESP]; Santana, Lucimeire A. [UNIFESP]; Silva-Lucca, Rosemeire A.; Lima, Amanda L. R.; Ferreira, Joana G. [UNIFESP]; Paiva, Patricia M. G.; Coelho, Luana C. B. B.; Oliva, Maria L. V. [UNIFESP]; Zingali, Russolina B.; Correia, Maria T. S. (Elsevier B.V., 2011-01-01)
      Lectins, proteins which recognize selectively carbohydrates, have been used as affinity chromatography to purify glycoproteins. Cratylia mollis seed lectin (Cramoll 1,4), of mannose/glucose binding class, immobilized on ...

    • Influence of the intestinal anticoagulant in the feeding performance of triatomine bugs (Hemiptera; Reduviidae) 

      Paim, Rafaela M. M.; Araujo, Ricardo N.; Soares, Adriana C.; Dhom Lemos, Lucas C.; Tanaka, Aparecida S. [UNIFESP]; Gontijo, Nelder F.; Lehane, Michael J.; Pereira, Marcos H. (Elsevier B.V., 2011-06-01)
      Triatomines are haematophagous insects in all post-embryonic life stages. They are vectors of Ttypanosoma cruzi, the causative agent of Chagas disease. Their vectorial ability is influenced by their feeding performance, ...

    • A non-hemorrhagic hybrid heparin/heparan sulfate with anticoagulant potential 

      Brito, Adriana S.; Cavalcante, Romulo S.; Palhares, Lais C. G. F.; Hughes, Ashley J.; Andrade, Giulianna P. V.; Yates, Edwin Alexander [UNIFESP]; Nader, Helena Bonciani [UNIFESP]; Lima, Marcelo Andrade de [UNIFESP]; Chavante, Suely F. (Elsevier B.V., 2014-01-02)
      The structural characterization and the anticoagulant potential of a novel heparin/heparan sulfate-like compound from the heads of Litopenaeus vannamei shrimp are described. While it is distinct from either heparin or ...

    • A sulfated polysaccharide, fucans, isolated from brown algae Sargassum vulgare with anticoagulant, antithrombotic, antioxidant and anti-inflammatory effects 

      Guerra Dore, Celina Maria P.; Faustino Alves, Monique Gabriela das C.; Pofirio Will, Luiza Sheyla E.; Costa, Thiago G.; Sabry, Diego A. [UNIFESP]; Souza Rego, Leonardo Augusto R. de; Accardo, Camila de Melo [UNIFESP]; Rocha, Hugo Alexandre O. .; Filgueira, Luciana Guimaraes A.; Leite, Edda Lisboa (Elsevier B.V., 2013-01-02)
      Fucan (SV1) sulfated polysaccharides from the brown algae Sargassum vulgare were extracted, fractionated in acetone and examined with respect to chemical composition, anticoagulant, anti-inflammatory, antithrombotic effects ...

    • Tick salivary gland as potential natural source for the discovery of promising antitumor drug candidates 

      Chudzinski-Tavassi, Ana Marisa; Morais, Katia L. P. [UNIFESP]; Pacheco, Mario Thiego Fernandes; Pasqualoto, Kerly Fernanda Mesquita; de Souza, Jean Gabriel [UNIFESP] (Elsevier France-Editions Scientifiques Medicales Elsevier, 2016)
      Nowadays, the relationship between cancer blood coagulation is well established. Regarding biodiversity and bioprospection, the tick biology has become quite attractive natural source for coagulation inhibitors, since its ...

    • Tick salivary gland as potential natural source for the discovery of promising antitumor drug candidates 

      Chudzinski-Tavassi, Ana Marisa; Morais, Katia L. P. [UNIFESP]; Pacheco, Mario Thiego Fernandes; Pasqualoto, Kerly Fernanda Mesquita; de Souza, Jean Gabriel [UNIFESP] (Elsevier France-Editions Scientifiques Medicales Elsevier, 2016)
      Nowadays, the relationship between cancer blood coagulation is well established. Regarding biodiversity and bioprospection, the tick biology has become quite attractive natural source for coagulation inhibitors, since its ...