Browsing by Subject "Annexin A1"
Now showing items 1-5 of 5
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Annexin A1 protein attenuates cyclosporine-induced renal hemodynamics changes and macrophage infiltration in rats
(Springer, 2012-03-01)Cyclosporine (CsA) remains an important immunosuppressant for transplantation and for treatment of autoimmune diseases. the most troublesome side effect of CsA is renal injury. Acute CsA-induced nephrotoxicity is characterized ...
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Interaction of the Anti-Inflammatory Annexin A1 Protein and Tacrolimus Immunosuppressant in the Renal Function of Rats
(Karger, 2010-01-01)Background: Tacrolimus (FK) is currently widely used in transplant immunosuppression and the treatment of autoimmune diseases. However, FK induces nephrotoxicity which is characterized by functional and structural renal ...
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Role of the protein annexin A1 on the efficacy of anti-TNF treatment in a murine model of acute colitis
(Pergamon-Elsevier Science Ltd, 2016)TNF-alpha is involved in the mechanisms that initiate inflammatory bowel diseases (IBDs). Anti-TNF-alpha drugs, such as infliximab (IFX), cause non-responsiveness and side effects, indicating the need to investigate ...
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Targeting formyl peptide receptor 2 reduces leukocyte-endothelial interactions in a murine model of stroke
(Federation Amer Soc Exp Biol, 2015-05-01)Ischemia/reperfusion (I/R) injury following stroke can worsen patient outcome through excess inflammation. This study investigated the pharmacologic potential of targeting an endogenous anti-inflammatory circuit via formyl ...
