Now showing items 1-10 of 18

    • Anxiolytic-like effect of sweet orange aroma in Wistar rats 

      Faturi, Claudia de Brito [UNIFESP]; Leite, Jose Roberto [UNIFESP]; Alves, Pericles Barreto; Canton, Adriane Conte; Teixeira-Silva, Flavia (Elsevier B.V., 2010-05-30)
      Aromatherapy is the use of essential oils as an alternative treatment for medical purposes. Despite the lack of sufficient scientific proof, it is considered a holistic complementary therapy employed to enhance comfort and ...

    • Characterization of an animal model of severe sepsis associated with respiratory dysfunction 

      Azevedo, Luciano Cesar Pontes [UNIFESP]; Park, Marcelo; Noritomi, Danilo Teixeira; Maciel, Alexandre Toledo; Brunialti, Milena Karina Coló [UNIFESP]; Salomão, Reinaldo [UNIFESP] (Faculdade de Medicina / USP, 2007-01-01)
      PURPOSE: Pathophysiological studies in humans regarding sepsis are difficult to perform due to ethical and methodological concerns. In this context, animal models of sepsis can be useful to better understand this condition ...

    • Differences in neonatal exposure to estradiol or testosterone on ovarian function and hormonal levels 

      Marcondes, Rodrigo R.; Carvalho, Katia C.; Duarte, Daniele C.; Garcia, Natalia; Amaral, Vinicius C.; Simoes, Manuel J. [UNIFESP]; Lo Turco, Edson G. [UNIFESP]; Soares, Jose M.; Baracat, Edmund C.; Maciel, Gustavo A. R. (Elsevier B.V., 2015-02-01)
      Exposure to an excess of androgen or estrogen can induce changes in reproductive function in adult animals that resemble polycystic ovary syndrome in humans. However, considerable differences exist among several types of ...

    • Effects of A1 receptor agonist/antagonist on spontaneous seizures in pilocarpine-induced epileptic rats 

      Amorim, Beatriz Oliveira; Hamani, Clement; Ferreira, Elenn; Miranda, Maisa Ferreira; Fernandes, Maria Jose S.; Rodrigues, Antonio M.; de Almeida, Antonio-Carlos G.; Covolan, Luciene (Academic Press Inc Elsevier Science, 2016)
      Adenosine is an endogenous anticonvulsant that activates pre- and postsynaptic adenosine A(1) receptors. A(1) receptor agonists increase the latency for the development of seizures and status epilepticus following pilocarpine ...

    • Effects of experimental sleep deprivation on anxiety-like behavior in animal research: Systematic review and meta-analysis 

      Pires, Gabriel Natan [UNIFESP]; Bezerra, Andreia Gomes [UNIFESP]; Tufik, Sergio [UNIFESP]; Andersen, Monica Levy [UNIFESP] (Pergamon-Elsevier Science Ltd, 2016)
      Increased acute anxiety is a commonly reported behavioral consequence of sleep deprivation in humans. However, rodent studies conducted so far produced inconsistent results, failing to reproduce the same sleep deprivation ...

    • The effects of paradoxical sleep deprivation on amphetamine-induced behavioral sensitization in adult and adolescent mice 

      Kameda, Sonia R. [UNIFESP]; Fukushiro, Daniela F. [UNIFESP]; Trombin, Thais F. [UNIFESP]; Sanday, Leandro [UNIFESP]; Wuo-Silva, Raphael [UNIFESP]; Saito, Luis R. [UNIFESP]; Tufik, Sergio [UNIFESP]; D'Almeida, Vania [UNIFESP]; Frussa-Filho, Roberto [UNIFESP] (Elsevier B.V., 2014-08-30)
      Drug-induced behavioral sensitization (BS), paradoxical sleep deprivation (PSD) and adolescence in rodents are associated with changes in the mesolimbic dopaminergic system. We compared the effects of PSD on amphetamine-induced ...

    • Effects of psychostimulants and antipsychotics on serum lipids in an animal model for schizophrenia 

      Correia, Banny Silva Barbosa; Nani, João Victor [UNIFESP]; Ricardo, Raniery Waladares; Stanisic, Danijela; Costa, Tássia Brena Barroso Carneiro; Hayashi, Mirian Akemi Furuie [UNIFESP]; Tasic, Ljubica (MDPI AG, 2021-02-26)
      Schizophrenia (SCZ) treatment is essentially limited to the use of typical or atypical antipsychotic drugs, which suppress the main symptoms of this mental disorder. Metabolic syndrome is often reported in patients with ...

    • Effects of the oestrogen receptor antagonist Fulvestrant on expression of genes that affect organization of the epididymal epithelium 

      Pereira, Marcos Fragoso de Noronha [UNIFESP]; Fernandes, Sheilla Alessandra Ferreira [UNIFESP]; Nascimento, Aline Rosa [UNIFESP]; Siu, Erica Rosanna [UNIFESP]; Hess, Rex A.; Oliveira, Cleida Aparecida de; Porto, Catarina Segreti [UNIFESP]; Lazari, Maria de Fatima Magalhaes [UNIFESP] (Wiley-Blackwell, 2014-07-01)
      The role of oestrogens in epididymal function is still unclear. Knockout of the oestrogen receptor ESR1 (Esr1-/-) or treatment with the anti-oestrogen Fulvestrant affect epididymal milieu and sperm motility. We investigated ...

    • Fibromyalgia and Sleep in Animal Models: A Current Overview and Future Directions 

      Frange, Cristina [UNIFESP]; Hirotsu, Camila [UNIFESP]; Hachul, Helena [UNIFESP]; Araujo, Paula [UNIFESP]; Tufik, Sergio [UNIFESP]; Andersen, Monica L. [UNIFESP] (Springer, 2014-08-01)
      Sleep disorders are highly prevalent in patients with fibromyalgia (FM). Many of the daytime symptoms, such as chronic pain and fatigue, may be related to the non-restorative sleep patterns associated with the disease. ...

    • Impact of adrenalectomy and dexamethasone treatment on testicular morphology and sperm parameters in rats: insights into the adrenal control of male reproduction 

      Silva, Erick José Ramo da [UNIFESP]; Vendramini, Vanessa [UNIFESP]; Restelli, Adriana Ester [UNIFESP]; Bertolla, Ricardo Pimenta [UNIFESP]; Kempinas, Wilma De Grava; Avellar, Maria Christina Werneck [UNIFESP] (Wiley-Blackwell, 2014-11-01)
      Here we investigated the hypothesis that normal levels of glucocorticoids, a class of adrenal steroid hormones, are required for normal testicular and epididymal functions. We examined the effects of the manipulation of ...